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David Bernard Gorenstein

from Highland Park, IL
Age ~75
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Also known as:
David B Gorenstein, David Annette Gorenstein, David Gorenstein Trus, David Gorenstien, David Gorestein, David N
Phone and address:
2021 Saint Johns Ave, Highland Park, IL 60035
Related to:
Shira G Gorenstein, 41Aron M Gorenstein, 51Benjamin GorensteinAnnette GorensteinMark BergerJennifer L Morin, 47Sam J GorensteinSarah A Preston, 50Jason L Gorenstein, 75Mariam B Gorenstein, 50Annette D Gorenstein, 75Sam GorensteinAdele J Gorenstein, 73Todd L Gorenstein, 47
Connected to:
Marc V Gorenstein, 73Michael J Gorenstein, 43Gerald J Gorentz, 72Victoria A Gorentz, 71Deborah Gorenz, 51Alida A Gores, 73Carissa Gores, 69Courtney M Gores, 33Frank C Gores, 79James P Gores, 69

David Gorenstein Phones & Addresses

  • 2021 Saint Johns Ave, Highland Park, IL 60035
  • Houston, TX
  • 4545 Touhy Ave, Lincolnwood, IL 60712
  • Chicago, IL
  • 900 Skokie Blvd, Northbrook, IL 60062
  • 12092 138Th St, Scottsdale, AZ 85259 (480) 614-1189
  • Lane, IL

Resumes

Resumes

David Gorenstein Photo 1

President

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Location:
Houston, TX
Industry:
Research
Work:
UT HSC Houston, School of Medicine since 2010
Associate Dean for Research
UT HSC Houston since 2009
Deputy Director, Institute of Molecular Medicine
AM Biotechnologies since 2007
Founder
Education:
Harvard University 1966 - 1969
Doctorates, Doctor of Philosophy, Philosophy, Chemistry Massachusetts Institute of Technology 1963 - 1966
Bachelors, Bachelor of Science, Chemistry
Skills:
Biochemistry
Protein Chemistry
Molecular Biology
Science
Life Sciences
Biotechnology
Bioinformatics
Lifesciences
Research
Cell Biology
Genomics
Genetics
Protein Purification
Cancer
Drug Discovery
Data Analysis
Chemistry
Cancer Research
R&D
Technology Transfer
Immunology
Pcr
Microscopy
Proteomics
Neuroscience
Public Speaking
Biophysics
Microbiology
Cell
Nanotechnology
Western Blotting
Structural Biology
Proposal Writing
Spectroscopy
Protein Expression
Grants
Grant Writing
Analysis
Scientific Writing
Hplc
Elisa
Leadership Development
Product Development
Start Ups
Dna
Computational Biology
Pharmacology
Higher Education
Animal Models
Organic Chemistry
David Gorenstein Photo 2

Associate Dean For Research

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Location:
Houston, TX
Industry:
Nanotechnology
Work:
The University of Texas System
Associate Dean for Research
Education:
Harvard University 1966 - 1969
David Gorenstein Photo 3

David Gorenstein

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David Gorenstein Photo 4

Professor And Deputy Director At Ut Hsc Houston

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Position:
Professor and Deputy Director at UT HSC Houston
Location:
Houston, Texas Area
Industry:
Biotechnology
Work:
UT HSC Houston
Professor and Deputy Director

Business Records

Name / Title
Company / Classification
Phones & Addresses
David G Gorenstein
Director
APTAMED, INC
Nonclassifiable Establishments
18 Cedar Lawn Cir, Galveston, TX 77551
12521 Gulf Fwy, Houston, TX 77034
3922 Crown Rdg Ct, Houston, TX 77059
David Gorenstein
Managing M, Managing
AM Biotechnologies, LLC
Biotechnology · Mfg Biological Products
12521 Gulf Fwy, Houston, TX 77034
3922 Crown Rdg Ct, Houston, TX 77059
David Gorenstein
President
Nevada Pickle Company Limited Partnership
6770 N Lincoln Ave, Chicago, IL 60712
David Gorenstein
Principal
6237 S. LANGLEY LLC
Nonclassifiable Establishments
2021 St Johns Ave STE P3, Highland Park, IL 60035
2021 Saint Johns Ave, Highland Park, IL 60035

Publications

Isbn (Books And Publications)

Phosphorus-31 Nmr: Principles and Applications

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Author

David G. Gorenstein

ISBN #

0122917502

Us Patents

Combinatorial Selection Of Oligonucleotide Aptamers

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US Patent:
6423493, Jul 23, 2002
Filed:
Oct 25, 1999
Appl. No.:
09/425798
Inventors:
David G. Gorenstein - Houston TX
David J. King - Galveston TX
Daniel A. Ventura - Galveston TX
Allan R. Brasier - Galveston TX
Assignee:
Board of Regents the University of Texas System - Austin TX
International Classification:
C12Q 168
US Classification:
435 6, 435 912, 435 71, 435DIG 47
Abstract:
A random combinatorial selection method is disclosed for the construction of oligonucleotide aptamers in which nuclease resistance is conferred by the inclusion of modified nucleotides. The modified nucleotides are incorporated during PCR amplification to form achiral modified oligonucleotides. Thio-substituted aptamers are provided that bind tightly to the nuclear factor for human IL6 (NF-IL6).

Thio-Modified Aptamer Synthetic Methods And Compositions

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US Patent:
6867289, Mar 15, 2005
Filed:
Oct 25, 1999
Appl. No.:
09/425804
Inventors:
David G. Gorenstein - Houston TX, US
Bruce A. Luxon - Galveston TX, US
Norbert Herzog - Friendswood TX, US
Judy Aronson - Galveston TX, US
Assignee:
Board of Regents, The University of Texas Systems - Austin TX
International Classification:
C07H021/04
C07K014/00
US Classification:
536 231, 530350
Abstract:
This invention generally relates the generation of aptamers and to the use of aptamers as diagnostic and therapeutic agents. More particularly, the present invention relates to methods using combinatorial chemistry to prepare aptamers having controlled thiophosphate replacement in the phosphate backbone for improved binding efficiencies to a target and to RNA and/or DNA products having novel nucleotide sequences and enhanced target binding efficacies.

Combinatorial Selection Of Oligonucleotide Aptamers

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US Patent:
7179894, Feb 20, 2007
Filed:
Apr 11, 2002
Appl. No.:
10/120815
Inventors:
David G. Gorenstein - Houston TX, US
David J. King - Galveston TX, US
Daniel A. Ventura - Galveston TX, US
Allan R. Brasier - Galveston TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
C07H 21/02
C07H 21/04
C12Q 1/68
US Classification:
536 231, 536 245, 435 6
Abstract:
A random combinatorial selection method is disclosed for the construction of oligonucleotide aptamers in which nuclease resistance is conferred by the inclusion of modified nucleotides. The modified nucleotides are incorporated during PCR amplification to form achiral modified oligonucleotides. Thio-substituted aptamers are provided that bind tightly to the nuclear factor for human IL6 (NF-IL6).

Bead Bound Combinatorial Oligonucleoside Phosphorothioate And Phosphorodithioate Aptamer Libraries

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US Patent:
7338762, Mar 4, 2008
Filed:
Apr 21, 2004
Appl. No.:
10/828935
Inventors:
David G. Gorenstein - Houston TX, US
Xianbin Yang - Webster TX, US
Bruce A. Luxon - Galveston TX, US
Norbert Herzog - Friendswood TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
C12Q 1/68
C07K 7/00
US Classification:
435 6, 435 5, 435 4, 435DIG 14, 435DIG 17, 536 231, 536 11
Abstract:
The present invention includes composition and methods for making and using a combinatorial library having two or more beads, wherein attached to each bead is a unique nucleic acid aptamer that have disposed thereon a unique sequence. The library aptamers may be attached covalently to the one or more beads, which may be polystyrene beads. The aptamers may include phosphorothioate, phosphorodithioate and/or methylphosphonate linkages and may be single or double stranded DNA, RNA or even PNAs.

Process And Apparatus For Combinatorial Synthesis

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US Patent:
7576037, Aug 18, 2009
Filed:
Nov 18, 2005
Appl. No.:
11/282800
Inventors:
Johnnie Paul Engelhardt - West Columbia TX, US
David G. Gorenstein - Houston TX, US
Bruce A. Luxon - Galveston TX, US
Assignee:
MEI Technologies, Inc. - Houston TX
Bd. of Regents, Univ. of Texas - Austin TX
International Classification:
C40B 60/02
C40B 60/08
B01J 10/00
B01J 12/02
US Classification:
506 34, 506 37, 422129
Abstract:
Apparatus and methods are described for split synthesis combinatorial chemistry that provides candidate libraries where an even distribution of theoretical products is obtainable through even mixing during the pooling step, followed by controlled redistribution of the mixed pooled products from the prior addition step into separate synthesis columns, one for each different specie of subunit to be added.

Structure Based And Combinatorially Selected Oligonucleoside Phosphorothioate And Phosphorodithioate Aptamer Targeting Ap-1 Transcription Factors

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US Patent:
7910523, Mar 22, 2011
Filed:
May 20, 2004
Appl. No.:
10/851864
Inventors:
David G. Gorenstein - Houston TX, US
Bruce A. Luxon - Galveston TX, US
James Leary - Galveston TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
International Classification:
C40B 50/16
US Classification:
506 31, 506 5, 506 26, 506 16
Abstract:
The present invention includes composition and methods for making and using a combinatorial library to identify modified thioaptamers that bind to, and affect the immune response of a host animal, transcription factors such as IL-6, NF-κB, AP-1 and the like. Composition and methods are also provided for the treatment of viral infections, as well as, vaccines and vaccine adjuvants are provided that modify host immune responses.

Phosphoromonothioate And Phosphorodithioate Oligonucleotide Aptamer Chip For Functional Proteomics

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US Patent:
20030162190, Aug 28, 2003
Filed:
Aug 6, 2002
Appl. No.:
10/214417
Inventors:
David Gorenstein - Houston TX, US
Bruce Luxon - Galveston TX, US
Norbert Herzog - Friendswood TX, US
Xian Yang - Webster TX, US
International Classification:
C12Q001/68
C12M001/34
US Classification:
435/006000, 435/287200
Abstract:
An apparatus and method for monitoring biological interactions is disclosed. The apparatus includes a substrate, a modified nucleotide aptamer attached to the substrate, a target molecule or portion thereof, wherein the interaction between the modified nucleotide aptamer and the target molecule or portion thereof is detected.

Thio-Sirna Aptamers

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US Patent:
20040242521, Dec 2, 2004
Filed:
Jan 15, 2004
Appl. No.:
10/758488
Inventors:
David Gorenstein - Houston TX, US
Xianbin Yang - Webster TX, US
Jonghoon Kang - Galveston TX, US
Assignee:
Board Of Regents, The University Of Texas System - Austin TX
International Classification:
A61K048/00
C07H021/02
US Classification:
514/044000, 536/023100
Abstract:
The present invention includes thioaptamers, methods and libraries for the isolation, selection, improvement, characterization and use of RNA thioaptamers for gene silencing, including degradative and non-degradative interference with translation.
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David Bernard Gorenstein from Highland Park, IL, age ~75 Get Report