Search

Yigal S Koltin

from Chestnut Hill, MA
Age ~87
Get Report
Related to:
Sara Koltin, 86
Connected to:
Todd A Koltis, 42Heather A Koltko, 34Patricia A Koltko, 71Wanda A Koltnow, 74Aloysius F Kolton, 102Bethany A Kolton, 33Carol R Kolton, 81Harper Kolton, 31James K Kolton, 32Jill S Kolton, 57

Yigal Koltin Phones & Addresses

  • 250 Hammond Pond Pkwy, Chestnut Hill, MA 02467 (617) 527-8958
  • 250 Hammond Pond Pkwy #512N, Chestnut Hill, MA 02467 (617) 527-8958
  • 75 Sidney St, Cambridge, MA 02139
  • Cincinnati, OH
  • 199 Parker St, Newton, MA 02459 (617) 630-5279
  • Newton Center, MA
  • Brookline, MA
  • Phoenixville, PA

Business Records

Name / Title
Company / Classification
Phones & Addresses
Yigal Koltin
Director
Cliniworks
Computer Software · Information Retrieval Services
245 1 St SUITE 1800, Cambridge, MA 02142
411 Waverley Oaks Rd, Waltham, MA 02452
(877) 549-1153, (617) 494-5500

Publications

Us Patents

Essential Fungal Genes And Their Use

View page
US Patent:
6461826, Oct 8, 2002
Filed:
Jul 23, 2001
Appl. No.:
09/911927
Inventors:
Yigal Koltin - Newton MA
Victoria Gavrias - Upton MA
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 168
US Classification:
435 731, 4352543, 4353201, 536 231, 536 245
Abstract:
Disclosed are essential Aspergillus polypeptides and genes (AN97, AN17, AN80, and AN85), as well as homologs thereof, which can be used to identify antifungal agents for treating fungal infections such as aspergillosis.

Essential Fungal Genes And Their Use

View page
US Patent:
6465198, Oct 15, 2002
Filed:
Jul 23, 2001
Appl. No.:
09/911882
Inventors:
Yigal Koltin - Newton MA
Victoria Gavrias - Upton MA
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07H 2104
US Classification:
435 731, 4352543, 4353201, 536 231, 536 245
Abstract:
Disclosed are essential Aspergillus polypeptides and genes (AN97, AN17, AN80, and AN85), as well as homologs thereof, which can be used to identify antifungal agents for treating fungal infections such as aspergillosis.

Essential Fungal Genes And Their Use

View page
US Patent:
6514715, Feb 4, 2003
Filed:
Jul 23, 2001
Appl. No.:
09/911888
Inventors:
Yigal Koltin - Newton MA
Victoria Gavrias - Upton MA
Assignee:
Millenium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07H 2104
US Classification:
435 731, 4352543, 4353201, 536 231, 536 245
Abstract:
Disclosed are essential Aspergillus polypeptides and genes (AN97, AN17, AN80, and AN85), as well as homologs thereof, which can be used to identify antifungal agents for treating fungal infections such as aspergillosis.

Essential Fungal Genes And Their Use

View page
US Patent:
62809636, Aug 28, 2001
Filed:
Nov 7, 1997
Appl. No.:
8/965762
Inventors:
Yigal Koltin - Newton MA
Victoria Gavrias - Upton MA
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
G01N 3353
C12Q 168
C07H 2104
US Classification:
435 731
Abstract:
Disclosed are essential Aspergillus polypeptides and genes (AN97, AN17, AN80, and AN85), as well as homologs of, which can be used to identify antifungal agents for treating fungal infections such as aspergillosis.

Identification Of Eukaryotic Growth-Related Genes And Promoter Isolation Vector And Method Of Use

View page
US Patent:
62515934, Jun 26, 2001
Filed:
May 27, 1998
Appl. No.:
9/084346
Inventors:
Yigal Koltin - Newton MA
Perry Riggle - Norwood MA
Vicky Gavrias - Watertown MA
Chris Bulawa - Arlington MA
Kenneth R. Winter - Seattle WA
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 168
C12N 114
C12N 1563
C07H 2104
US Classification:
435 6
Abstract:
A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described. The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i. e. , promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i. e. , promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.

Identification Of Eukaryotic Growth-Related Genes And Promoter Isolation Vector And Method Of Use

View page
US Patent:
60201339, Feb 1, 2000
Filed:
Jan 8, 1998
Appl. No.:
9/004225
Inventors:
Yigal Koltin - Newton MA
Perry Riggle - Norwood MA
Vicky Gavrias - Upton MA
Chris Bulawa - Arlington MA
Ken Winter - Sunshine Canyon Boulder CO
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C12Q 168
C12Q 148
C12N 910
A61K 3845
US Classification:
435 6
Abstract:
A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described. The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i. e. , promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i. e. , promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.

Identification Of Eukaryotic Growth-Related Genes And Promoter Isolation Vector And Method Of Use

View page
US Patent:
58245456, Oct 20, 1998
Filed:
Nov 1, 1995
Appl. No.:
8/551437
Inventors:
Yigal Koltin - Newton MA
Perry Riggle - Norwood MA
Vicky Gavrias - Watertown MA
Chris Bulawa - Arlington MA
Ken Winter - Cambridge MA
Assignee:
Millennium Pharaceuticals, Inc. - Cambridge MA
International Classification:
C12N 1500
US Classification:
4353201
Abstract:
A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described. The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i. e. , promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i. e. , promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.
Control profile
Yigal S Koltin from Chestnut Hill, MA, age ~87 Get Report