Search

Xueming M Qian

from Thousand Oaks, CA
Age ~56

Xueming Qian Phones & Addresses

  • 2467 Vista Wood Cir, Thousand Oaks, CA 91362 (805) 241-1731
  • 587 Ventu Park Rd, Newbury Park, CA 91320
  • 596 Myrtle Ct, Oak Park, CA 91377 (818) 597-4872 (818) 636-6185
  • Agoura Hills, CA
  • Ventura, CA
  • Sacramento, CA
  • New York, NY
  • 596 Myrtle Ct, Oak Park, CA 91377 (818) 636-6185

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Publications

Us Patents

Therapeutic Human Anti-Il-1R1 Monoclonal Antibody

View page
US Patent:
8236559, Aug 7, 2012
Filed:
Sep 15, 2008
Appl. No.:
12/210313
Inventors:
Brian Varnum - Santa Monica CA, US
Chris Vezina - Newbury Park CA, US
Alison Witte - Scotts Valley CA, US
Xueming Qian - Oak Park CA, US
Francis Hall Martin - Newbury Park CA, US
Haichun Huang - Fremont CA, US
Gary Elliott - Thousand Oaks CA, US
Assignee:
Medarex, Inc. - Princeton NJ
Amgen Inc. - Thousand Oaks CA
International Classification:
C12N 5/16
US Classification:
435326, 536 2351
Abstract:
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.

Wise Binding Agents And Epitopes

View page
US Patent:
8309092, Nov 13, 2012
Filed:
Sep 15, 2011
Appl. No.:
13/233983
Inventors:
Xueming Qian - Oak Park CA, US
Kevin Graham - Thousand Oaks CA, US
Grant Shimamoto - Newbury Park CA, US
Barbara S. Tipton - Thousand Oaks CA, US
Mei-Mei Tsai - Thousand Oaks CA, US
Aaron George Winters - Ventura CA, US
Li Zhang - Fremont CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 39/395
C07K 16/22
C07K 16/46
US Classification:
4241581, 4241421, 4241821, 53038815, 53038824
Abstract:
The present invention relates to binding agents for WISE, and includes for their manufacture and use.

Therapeutic Human Anti-Il-1R1 Monoclonal Antibody

View page
US Patent:
8518407, Aug 27, 2013
Filed:
Apr 18, 2012
Appl. No.:
13/450126
Inventors:
Brian Varnum - Santa Monica CA, US
Chris Vezina - Newbury Park CA, US
Alison Witte - Scotts Valley CA, US
Xueming Qian - Oak Park CA, US
Francis Hall Martin - Newbury Park CA, US
Haichun Huang - Fremont CA, US
Gary Elliott - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
Medarex, Inc. - Princeton NJ
International Classification:
A61K 39/395
US Classification:
4241441, 4241541
Abstract:
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.

Wise Binding Agents And Epitopes

View page
US Patent:
8043620, Oct 25, 2011
Filed:
Nov 21, 2008
Appl. No.:
12/275850
Inventors:
Xueming Qian - Oak Park CA, US
Kevin Graham - Thousand Oaks CA, US
Grant Shimamoto - Newbury Park CA, US
Barbara S. Tipton - Thousand Oaks CA, US
Mei-Mei Tsai - Thousand Oaks CA, US
Aaron George Winters - Ventura CA, US
Li Zhang - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
A61K 39/395
C07K 16/22
C07K 16/46
US Classification:
4241581, 4241421, 4241821, 53038815, 53038824
Abstract:
The present invention relates to binding agents for WISE, and includes for their manufacture and use.

Antibodies And Other Selective Il-1 Binding Agents That Allow Binding To Il-1 Receptor But Not Activation Thereof

View page
US Patent:
20030026806, Feb 6, 2003
Filed:
Oct 29, 2001
Appl. No.:
10/011931
Inventors:
Alison Witte - Camarillo CA, US
Brian Varnum - Santa Monica CA, US
Xueming Qian - Oak Park CA, US
Chris Vezina - Newbury Park CA, US
Assignee:
Amgen Inc.
International Classification:
A61K039/395
C12N015/86
C12P021/02
US Classification:
424/145100, 435/069100, 435/456000
Abstract:
The invention concerns methods of treating IL-1-mediated disease by administering a selective IL-1 binding agents that form an antagonist complex with the IL-1 ligand. The antagonist complex can bind to the IL-1 receptor without activating the receptor. The selective binding agents contemplated by this invention thus have the properties of free ligand absorption (through binding of the selective binding agent to free IL-1 or ) and receptor activation inhibition (through binding of the antagonist complex to the receptor and preventing its activation).

Therapeutic Human Anti-Il1-R1 Monoclonal Antibody

View page
US Patent:
20040097712, May 20, 2004
Filed:
Sep 5, 2003
Appl. No.:
10/656769
Inventors:
Brian Varnum - Santa Monica CA, US
Chris Vezina - Newbury Park CA, US
Alison Witte - Scotts Valley CA, US
Xueming Qian - Oak Park CA, US
Francis Martin - Newbury Park CA, US
Haichun Huang - Fremont CA, US
Gary Elliott - Thousand Oaks CA, US
Assignee:
Amgen, Inc. A Corporation of the State of Delaware
International Classification:
C07K016/28
US Classification:
530/388220
Abstract:
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.

Screening Method For Antibodies And Other Selective Il-1 Binding Agents That Allow Binding To Il-1 Receptor But Not Activation Thereof

View page
US Patent:
20050084493, Apr 21, 2005
Filed:
Nov 9, 2004
Appl. No.:
10/985299
Inventors:
Alison Witte - Camarillo CA, US
Brian Varnum - Santa Monica CA, US
Xueming Qian - Oak Park CA, US
Chris Vezina - Newbury Park CA, US
International Classification:
A61K039/395
C07K016/24
US Classification:
424145100, 424141100, 530388230
Abstract:
The invention concerns methods of treating IL-1-mediated disease by administering a selective IL-1 binding agents that form an antagonist complex with the IL-1 ligand. The antagonist complex can bind to the IL-1 receptor without activating the receptor. The selective binding agents contemplated by this invention thus have the properties of free ligand absorption (through binding of the selective binding agent to free IL-1α or β) and receptor activation inhibition (through binding of the antagonist complex to the receptor and preventing its activation).

Wise Binding Agents And Epitopes

View page
US Patent:
20120288507, Nov 15, 2012
Filed:
Dec 17, 2010
Appl. No.:
13/516161
Inventors:
Xueming Qian - Oak Park CA, US
Aaron George Winters - Ventura CA, US
Michelle Hortter - Camarillo CA, US
Kevin Graham - Thousand Oaks CA, US
Mei-Mei Tsai - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07K 16/18
A61P 13/12
C07K 19/00
A61K 39/395
C07K 14/47
US Classification:
4241391, 5303891, 5303879, 530350, 4241721, 530362, 5303911
Abstract:
The present invention relates to binding agents for WISE, and includes methods for their manufacture and use.
Xueming M Qian from Thousand Oaks, CA, age ~56 Get Report