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Xiaorui R Yao

from Waltham, MA
Age ~69
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Also known as:
Xiao Rui Yao, Xiao R Yao, Yao Xiaorui, Xiao Rui O
Related to:
Mihye Yang, 58Yu Zhang, 40Peng Zhang, 61Renfei Yan, 39Richard Chen, 56Miles Chan, 36
Connected to:
Alan P Yao, 72Albert R Yao, 76Allan Y Yao, 29Amy Yao, 57Angie Yao, 46Anni N Yao, 74Bianca T Yao, 62Brandon Yao, 29Carmen Yao, 35Chantal Yao, 48

Xiaorui Yao Phones & Addresses

  • Waltham, MA
  • 160 Buttonwood Dr, Piscataway, NJ 08854 (732) 302-0149
  • Rockville, MD
  • 95 Kelly Dr, Edison, NJ 08820 (732) 548-6972
  • Scotch Plains, NJ
  • 160 Buttonwood Dr, Piscataway, NJ 08854

Work

Company: Molecular biomarkers, merck - Kenilworth, NJ Jan 2010 Position: Sr. scientist, assay development

Education

School / High School: Bethune Medical University- Changchun, CN 1979 Specialities: M. Sc. in Immunology

Resumes

Resumes

Xiaorui Yao Photo 1

Xiaorui Yao

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Location:
Piscataway, NJ
Industry:
Pharmaceuticals
Work:
Merck 1996 - 2010
Senior Scientist
Xiaorui Yao Photo 2

Scientis

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Location:
Piscataway, NJ
Industry:
Pharmaceuticals
Work:
Novartis
Scientis
Education:
Jilin Medical University
Xiaorui Yao Photo 3

Xiaorui Yao Piscataway, NJ

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Work:
Molecular Biomarkers, Merck
Kenilworth, NJ
Jan 2010 to Oct 2013
Sr. Scientist, Assay Development
Schering-Plough
Kenilworth, NJ
Feb 1996 to Dec 2009
Scientist II in CV Biology Research
Immunology Division
Rockville, MD
Apr 1994 to Feb 1996
Research Scientist
Immunology, University of Rochester
Rochester, NY
Jul 1990 to Mar 1994
Research Associate
Immunology, China-Japan Friendship Hospital

Sep 1982 to Jun 1990
Research Fellow
Immunology, China-Japan Friendship Hospital
Worcester, MA
Feb 1986 to Sep 1986
Visiting Research Fellow
Immunology, China-Japan Friendship Hospital
Groningen
Mar 1984 to Sep 1985
Visiting Research Fellow
Education:
Bethune Medical University
Changchun, CN
1979 to 1982
M. Sc. in Immunology
Jilin Medical University
Changchun, CN
1973 to 1977
B. Sc. in Medicine
Schering-Plough Research Institute
research

Publications

Us Patents

Use Of Azetidinone Compounds

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US Patent:
6632933, Oct 14, 2003
Filed:
Jul 30, 2001
Appl. No.:
09/918397
Inventors:
Scott W. Altmann - Fanwood NJ
Duane A. Burnett - Bernardsville NJ
Michael P. Graziano - Scotch Plains NJ
Maureen Laverty - Metuchen NJ
Xiaorui Yao - Edison NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07H 1526
US Classification:
536 174, 540200, 548405, 549224, 514 23, 51421002
Abstract:
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.

Use Of Azetidinone Compounds

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US Patent:
6933107, Aug 23, 2005
Filed:
May 15, 2003
Appl. No.:
10/438637
Inventors:
Scott W. Altmann - Fanwood NJ, US
Duane A. Burnett - Bernardsville NJ, US
Michael P. Graziano - Scotch Plains NJ, US
Maureen Laverty - Metuchen NJ, US
Xiaorui Yao - Edison NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12Q001/68
C07K014/47
US Classification:
435 4, 435 71, 435 72, 435 721, 514 23, 51421002
Abstract:
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.

Use Of Azetidinone Compounds

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US Patent:
7144696, Dec 5, 2006
Filed:
May 6, 2005
Appl. No.:
11/123615
Inventors:
Scott W. Altmann - Fanwood NJ, US
Duane A. Burnett - Bernardsville NJ, US
Michael P. Graziano - Scotch Plains NJ, US
Maureen Laverty - Metuchen NJ, US
Xiaorui Yao - Edison NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12Q 1/00
G01N 33/53
A01N 43/04
US Classification:
435 4, 435 71, 435 72, 435 721, 514 23, 51421002
Abstract:
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.

Use Of Azetidinone Compounds

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US Patent:
7723020, May 25, 2010
Filed:
Oct 25, 2006
Appl. No.:
11/586303
Inventors:
Scott W. Altmann - Fanwood NJ, US
Duane A. Burnett - Bernardsville NJ, US
Michael P. Graziano - Scotch Plains NJ, US
Maureen Laverty - Old Bridge NJ, US
Xiaorui Yao - Piscataway NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12Q 1/00
G01N 33/53
G01N 33/567
A01N 43/04
A61K 31/397
US Classification:
435 4, 435 71, 435 72, 435 721, 514 23, 51421002
Abstract:
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.

Npc1L1 Orthologues

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US Patent:
7910698, Mar 22, 2011
Filed:
Feb 22, 2007
Appl. No.:
11/710295
Inventors:
Scott Altmann - Asbury Park NJ, US
Xiaorui Yao - Piscataway NJ, US
Kim Ann O'Neill - Scotch Plains NJ, US
Brian E. Hawes - Hillsborough NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07K 14/00
C12N 11/00
C12P 21/06
C12P 21/04
C12Q 1/00
G01N 33/567
G01N 33/53
G01N 33/00
C12Q 1/16
A01N 37/18
A61K 38/16
A61K 38/00
US Classification:
530350, 435174, 435 691, 435 697, 435 4, 435 721, 435 771, 435 78, 435 793, 435 35, 514 2, 514 8, 514 21
Abstract:
The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e. g. , in screening assays, are also set forth.

Npc1L1 Orthologues

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US Patent:
8212016, Jul 3, 2012
Filed:
Feb 14, 2011
Appl. No.:
13/026763
Inventors:
Scott W. Altmann - Asbury Park NJ, US
Xiaorui Yao - Piscataway NJ, US
Kim Anne O'Neill - Scotch Plains NJ, US
Brian E. Hawes - Hillsborough NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07H 21/02
C12P 21/06
C12N 15/00
C12N 5/00
C12N 1/20
C12N 1/00
C12N 5/04
C12N 5/10
US Classification:
536 231, 4353201, 435 691, 435325, 4352523, 43525411, 435419, 4352542
Abstract:
The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e. g. , in screening assays, are also set forth.

Nrip1 Regulation Of Apolipoprotein A1

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US Patent:
8257921, Sep 4, 2012
Filed:
Dec 22, 2009
Appl. No.:
12/644674
Inventors:
Xiaorui Yao - Piscataway NJ, US
Scott W. Altmann - Asbury Park NJ, US
Liji Zhu - Oakland Gardens NY, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12Q 1/68
US Classification:
435 61
Abstract:
The present invention provides, in part, methods for identifying inhibitors of NRIP1 and methods of using such inhibitors. Methods of treating NRIP1-mediated disorders using NRIP1 inhibitor are also provided.

Use Of Azetidinone Compounds

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US Patent:
6593078, Jul 15, 2003
Filed:
Apr 12, 2000
Appl. No.:
09/547509
Inventors:
Scott W. Altmann - Fanwood NJ
Duane A. Burnett - Bernardsville NJ
Michael P. Graziano - Scotch Plains NJ
Maureen Laverty - Metuchen NJ
Xiaorui Yao - Edison NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C12Q 100
US Classification:
435 4, 435 6, 435 71, 435 721, 514 23, 51421002
Abstract:
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
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Xiaorui R Yao from Waltham, MA, age ~69 Get Report