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William J Lapps

from Nazareth, PA
Age ~70
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Also known as:
Bill J Lapps, William Laps
Phone and address:
1240 Seifert Rd, Nazareth, PA 18064
Related to:
Darren R Reynolds, 49Lucinda Reynolds, 51Deshea Harris, 53Young J Jo, 51Sun H Kim, 65
Connected to:
Frank Lapps, 75Adam S Laprad, 41Brittany Laprad, 35Dawn A Laprad, 46Frank Laprad, 69Mabel A Laprada, 44Robert F Laprad, 57Billy J Laprade, 50David W Lapradd, 44Deborah J Laprade, 58

William Lapps Phones & Addresses

  • 1240 Seifert Rd, Nazareth, PA 18064
  • Athens, OH
  • Kailua, HI
  • 6415 Hickory Ln, Sykesville, MD 21784 (410) 781-7431
  • Roswell, NM
  • Dunellen, NJ
  • 1240 Seifert Rd, Nazareth, PA 18064 (610) 349-1203

Work

Position: Service Occupations

Education

Degree: Associate degree or higher

Publications

Us Patents

Cort-Pcr Assay For The Discrimination Of Endogenous Reverse Transcriptase Activity In Eukaryotic Cell Lines From Infectious Retrovirus Contamination

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US Patent:
20030008280, Jan 9, 2003
Filed:
Aug 9, 2002
Appl. No.:
10/216261
Inventors:
Scott Goebel - Ballston Spa NY, US
Maurice Harmon - Tannersville PA, US
Jim Tartaglia - North York, CA
William Lapps - Nazareth PA, US
Francois Pelloquin - Lyon, FR
Dennis Trent - Carbonniers, FR
International Classification:
C12Q001/70
C12Q001/68
C12P019/34
US Classification:
435/005000, 435/006000, 435/091200
Abstract:
The present invention relates to the detection of the presence of reverse transcriptase enzymatic activity in eukaryotic cell lines. Specifically, the present invention comprises a method for discriminating between endogenous reverse transcriptase activity in a substrate cell line (e.g., avian) used as substrates for the manufacture of biological products (including viral vaccines) from exogenous infectious retrovirus by using a combination of transmissibility assay (viral replication) and PBRT assay (RT-PCR). Appropriate levels of viral amplification and number of PCR cycles are determined and employed that permit detection of exogenous infectious RT activity but not endogenous RT activity.

Cort-Pcr Assay For The Discrimination Of Endogenous Reverse Transcriptase Activity In Eukaryotic Cell Lines From Infectious Retrovirus Contamination

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US Patent:
6465171, Oct 15, 2002
Filed:
Jun 14, 2000
Appl. No.:
09/594075
Inventors:
Scott Goebel - Ballston Spa NY
Maurice Harmon - Tannersville PA
Jim Tartaglia - North York, CA
William Lapps - Nazareth PA
Francois Pelloquin - Lyons, FR
Dennis W. Trent - Carbonniers, FR
Assignee:
Aventis Pasteur - Swiftwater PA
International Classification:
C12Q 170
US Classification:
435 5, 435 6, 435 911, 435 912
Abstract:
The present invention relates to the detection of the presence of reverse transcriptase enzymatic activity in eukaryotic cell lines. Specifically, the present invention comprises a method for discriminating between endogenous reverse transcriptase activity in a substrate cell line (e. g. , avian) used as substrates for the manufacture of biological products (including viral vaccines) from exogenous infectious retrovirus by using a combination of transmissibility assay (viral replication) and PBRT assay (RT-PCR). Appropriate levels of viral amplification and number of PCR cycles are determined and employed that permit detection of exogenous infectious RT activity but not endogenous RT activity.
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William J Lapps from Nazareth, PA, age ~70 Get Report