US Patent:
20040228839, Nov 18, 2004
Inventors:
Vassilios Avramis - Sylmar CA, US
Lewis Cohen - Pottstown PA, US
International Classification:
A61K038/21
A61K031/551
A61K038/05
US Classification:
424/085700, 514/220000, 514/352000, 514/018000, 514/575000
Abstract:
Method of inhibiting or treating Human Immunodeficiency Virus (HIV) infection, comprising administering to a patient in need thereof an effective amount of a pharmaceutically acceptable composition comprising a PEG-ASNase compound or asparaginase, and optionally at least one compound selected from the group consisting of protease inhibitor compounds, ribonucleotide reductase inhibitor compounds and HIV reverse transcriptase inhibitor compounds.