Inventors:
Thea D. Tlsty - San Francisco CA, US
Hal K. Berman - Toronto, CA
Mona L. Gauthier - Toronto, CA
Bob Y. Liu - San Francisco CA, US
Colleen A. Fordyce - San Francisco CA, US
Curtis R. Pickering - San Francisco CA, US
Paul A. Reynolds - San Francisco CA, US
Nancy Dumont - San Francisco CA, US
Geoffrey M. Benton - San Francisco CA, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
A61K 51/10
C12Q 1/68
G01N 33/567
A61K 49/00
A61K 51/06
A61K 51/00
A61K 49/14
A61K 49/16
A61K 49/04
A61K 49/06
A61K 49/12
A61P 35/00
US Classification:
424 149, 435 6, 435 721, 424 91, 424 96, 424 173, 424 169, 424 934, 424 935, 424 94, 424 943
Abstract:
Detection methods, assay kits and reagents are provided for detecting pre-cancerous mammary epithelial cell signatures. The disclosed cell signatures comprise a collection of measurements of at least two characteristics of the mammary epithelial cells. Related imaging and diagnostic methods are also disclosed.