Shridhara A Karinka

6863800, Mar 8, 2005

Feb 1, 2002

10/062313

Shridhara Alva Karinka - Lowell MA, US
Geoffrey Roger Chambers - Middlesex, GB
Gurdial Sanghera - Oxon, GB

Abbott Laboratories - Abbott Park IL

G01N027/327

2057775, 205792, 20440314, 20440311

A biosensor in the form of a strip. In one embodiment, the biosensor strip comprises an electrode support, a first electrode, i. e. , a working electrode, a second electrode, i. e. , a counter electrode, and a third electrode, i. e. , a reference electrode. Each of the electrodes is disposed on and supported by the electrode support. Each of the electrodes is spaced apart from the other two electrodes. The biosensor strip can include a covering layer, which defines an enclosed space over the electrodes. This enclosed space includes a zone where an analyte in the sample reacts with reagent(s) deposited at the working electrode. This zone is referred to as the reaction zone. The covering layer has an aperture for receiving a sample for introduction into the reaction zone. The biosensor strip can also include at least one layer of mesh interposed in the enclosed space between the covering layer and the electrodes in the reaction zone. This layer of mesh facilitates transporting of the sample to the electrodes in the reaction zone.

6939450, Sep 6, 2005

Oct 8, 2002

10/266548

Shridhara Alva Karinka - Lowell MA, US
Mark E. Tess - Merrimack NH, US

Abbott Laboratories - Abbott Park IL

G01N027/327
G01N021/00
B01L003/00
B01L003/02

204409, 20440301, 20440314, 422 58, 422 99

A device having a flow channel, wherein at least one flow-terminating interface is used to control the flow of liquid in the flow channel. The flow-terminating interface prevents the flow of the liquid beyond the interface. In one aspect, the invention provides a sensor, such as, for example, a biosensor, in the form of a strip, the sensor being suitable for electrochemical or optical measurement. The sensor comprises a base layer and a cover layer, and the base layer is separated from the cover layer by a spacer layer. The base layer, cover layer, and spacer layer define a flow channel into which a liquid sample is drawn therein and flows therethrough by means of capillary attraction. The flow of the sample is terminated by a flow-terminating interface positioned in the flow channel.

7086277, Aug 8, 2006

Feb 23, 2004

10/784764

Mark E. Tess - Merrimack NH, US
Scott L. Bailey - Burlington MA, US
Shridhara Alva Karinka - Chelmsford MA, US

Abbott Laboratories - Abbott Park IL

G01N 11/00
G01N 27/00

73 5301, 73 6141, 2044031, 20440314, 422 58, 422 8202

A device having a flow channel, wherein a layer of mesh is adhered to a surface forming a wall of a flow channel, but the layer of mesh is of such dimensions that the layer of mesh does not contact those portions of the device where electrochemical reactions occur and electrons flow. In one aspect, the invention provides a sensor, such as, for example, a biosensor, in the form of a strip, the sensor being suitable for electrochemical or optical measurement. The sensor comprises a base layer and a cover layer having a layer of mesh adhered thereto, and the base layer is separated from the cover layer by a spacer layer. The base layer, the cover layer having a layer of mesh adhered thereto, and the spacer layer define a flow channel into which a liquid sample is drawn therein and flows therethrough by means of wicking.

7357851, Apr 15, 2008

Sep 30, 2003

10/674955

Terence Alan Reid - Abingdon, GB
Shridhara Alva Karinka - Chelmsford MA, US
Milind P. Nagale - Lowell MA, US
Yi Wang - Southborough MA, US
Gurdial Sanghera - Oxon, GB

Abbott Laboratories - Abbott Park IL

G01N 27/327

20440304, 2044031, 20440314

An electrochemical cell for detection and quantification of analytes in a liquid sample, particularly a liquid sample having a small volume. In a preferred embodiment, the electrochemical cell comprises an assembly of conducting layers and insulating layers. The electrochemical cell can be formed by depositing conducting materials and insulating materials in alternating layers on an insulating substrate. It is preferred that the layer furthest from the insulating substrate be an insulating layer to minimize the damage of the conducting layers during handling of the electrochemical cell. In another embodiment, the assembly of conducting layers and insulating layers can be formed on both major surfaces of the insulating substrate. The assembly can comprise at least one working electrode and at least one other electrode, e. g. , a dual-purpose reference/counter electrode.

7501053, Mar 10, 2009

Oct 23, 2002

10/278657

Shridhara Alva Karinka - Lowell MA, US
W. James Scott - Bedford MA, US

Abbott Laboratories - Abbott Park IL

G01N 27/327

205792, 2057775, 20440314, 20440311, 20440304

A biosensor that utilizes a mediator, i. e. , an isomer of phenanthroline quinone, 1,10-phenanthroline-5,6-dione, and a metal ion, such as manganese, with an enzyme dependent upon NAD(P), such as, for example, glucose dehydrogenase, for improving the hematocrit bias and oxygen bias of biosensors. The electrodes of the biosensors employing this mediator and a metal ion provide an accurate clinical response over a hematocrit range that ranges from about 20% to about 70% and over an oxygen tension range that ranges from about 1 kPa to about 20 kPa.

D611854, Mar 16, 2010

Sep 30, 2009

29/344579

Yi Wang - Sam Ramon CA, US
Joseph A. Vivolo - San Francisco CA, US
Shridhara Alva Karinka - Pleasanton CA, US

Abbott Diabetes Care Inc. - Alameda CA

1004

D10 81

7754093, Jul 13, 2010

May 26, 2006

11/420628

Nigel J. Forrow - Abingdon, GB
Shridhara Alva Karinka - Pleasanton CA, US

Abbott Diabetes Care Inc. - Alameda CA

H01G 9/022
C12M 1/00
C12N 11/02
C12N 11/14
C12N 11/16

252 622, 252513, 252514, 20440301, 20440304, 20440309, 2044031, 20440311, 20440314

The present invention provides reagent compositions, and analyte measuring devices and methods that utilize the reagent compositions.

8066858, Nov 29, 2011

Oct 31, 2007

11/932658

Yi Wang - San Ramon CA, US
Joseph A. Vivolo - San Francisco CA, US
Shridhara Alva Karinka - Pleasanton CA, US

Abbott Diabetes Care Inc. - Alameda CA

G01N 27/416
G01N 27/327

204406, 20440302

A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.