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Sergey M Podkovyrov

from North Potomac, MD
Deceased
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Also known as:
Sergey Podkovyrova, Sergey A
Phone and address:
11216 Trippon Ct, Gaithersburg, MD 20878
(301) 294-8022
Related to:
Anna S Podkovyrova, 35Roza A Podkovyrov, 64
Connected to:
Bree A Podkowka, 43Neil E Podkowsky, 47Laura A Podkulski, 68Michael G Podkulski, 53Robert J Podlas, 85Brian J Podlasek, 50Evan G Podlaseck, 35Raymond J Podlasek, 79Vernon M Podlasek, 94Carole J Podlashes, 83

Sergey Podkovyrov Phones & Addresses

  • 11216 Trippon Ct, Gaithersburg, MD 20878 (301) 294-8022 (301) 527-9330
  • North Potomac, MD
  • 614 Washington St SE, Blacksburg, VA 24060 (540) 552-8952
  • East Lansing, MI
  • 11216 Trippon Ct, North Potomac, MD 20878 (301) 294-8022

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Publications

Us Patents

Vectors, Cells And Processes For Pyrimidine Deoxyribonucleosides Production

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US Patent:
7387893, Jun 17, 2008
Filed:
Aug 9, 2004
Appl. No.:
10/914529
Inventors:
David Martin Anderson - Rockville MD, US
Lin Liu - Rockville MD, US
Sergey Podkovyrov - Gaithersburg MD, US
Baomin Wang - Rockville MD, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 15/00
C12N 1/20
C12N 5/10
C07H 21/00
C12N 9/02
C12N 9/12
C12N 9/78
C12Q 1/26
C12P 21/06
C07K 14/00
US Classification:
4353201, 4352523, 435325, 43525233, 435189, 435 25, 435 691, 435194, 435227, 536 232, 530350
Abstract:
Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e. g. operon) comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin or a uridine kinase gene and/or a dCTP deaminase gene. In preferred embodiments the constructs comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin further comprise DNA sequences encoding for thymidylate synthase and/or transcription units comprising sequences encoding for uridine kinase preferably together with dCTP deaminase. In particularly preferred embodiments, the host cells comprise constructs having all of the above characteristics wherein the host cell displays repressed or no uracil DNA glycosylase activity. This may be achieved by removal of the host cell ung gene. Use of host cells in the manufacture of pyrimidine deoxyribonucleotides e. g.

Biological Production Of Thymidine

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US Patent:
8263384, Sep 11, 2012
Filed:
Feb 5, 2007
Appl. No.:
12/278227
Inventors:
David Martin Anderson - Gaithersburg MD, US
Andrew John Collis - Ulverston, GB
Lin Liu - Gaithersburg MD, US
Sergey Podkovyrov - Gaithersburg MD, US
Christopher Preston - Ulverston, GB
Assignee:
Glaxo Group Limited - Greenford, Middlesex
International Classification:
C12N 1/21
C12P 19/38
US Classification:
4352523, 435189, 4353201, 435 87
Abstract:
Novel organisms, including DNA construct host cell combinations, are disclosed. The organisms comprise a transcription unit (e. g. operon) comprising DNA sequences encoding for enzymes which promote the supply of single carbon units for the conversion of dUMP to dTMP. Examples include: dihydrofolate reductase genes e. g. T4 frd; Serine Hydroxymethyltransferase genes e. g. glyA; 3-phosphoglycerate dehydrogenase genes e. g. serA; and THF synthase genes e. g. ADE3. The organisms are used in a biological method of producing thymidine with significantly reduced levels of uridine.

Vectors, Cells And Processes For Pyrimidine Deoxyribonucleosides Production

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US Patent:
20020128457, Sep 12, 2002
Filed:
Jul 1, 1999
Appl. No.:
09/345492
Inventors:
DAVID MARTIN ANDERSON - ROCKVILLE MD, US
LIN LU - GAITHERSBURG MD, US
SERGEY PODKOVYROV - NORTH POTOMAC MD, US
BAOMIN WANG - GAITHERSBURG MD, US
International Classification:
C12N015/63
US Classification:
536/023200, 435/183000, 435/320100, 435/325000
Abstract:
Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e.g. operon) comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin. In preferred embodiments, constructs further comprise DNA sequences encoding for thymidylate synthase and/or transcription units comprising sequences encoding for uridine kinase preferably together with dCTP deaminase. In particularly preferred embodiments, host cells comprising constructs having all of the above characteristics wherein the host cell displays repressed or no uracil DNA glycosylase activity. This may be achieved by removal of the host cell ung gene. Use of host cells in the manufacture of pyrimidine deoxyribonucleotides e.g. thymidine is also disclosed.

Vectors, Cells And Processes For Pyrimidine Deoxyribonucleosides Production

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US Patent:
6777209, Aug 17, 2004
Filed:
Mar 6, 2002
Appl. No.:
10/018878
Inventors:
David Martin Anderson - Rockville MD
Lin Liu - Rockville MD
Sergey Podkovyrov - Gaithersburg MD
Baomin Wang - Rockville MD
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 120
US Classification:
435 87, 4353201, 435 691, 435325, 4352523, 435194, 435189, 435227, 43525233, 536 232, 530350
Abstract:
Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e. g. operon) comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin or a uridine kinase gene and/or a dCTP deaminase gene. In preferred embodiments the constructs comprising DNA sequences encoding for ribonucleotide reductase and thioredoxin further comprise DNA sequences encoding for thymidylate synthase and/or transcription units comprising sequences encoding for uridine kinase preferably together with dCTP deaminase. In particularly preferred embodiments, the host cells comprise constructs having all of the above characteristics wherein the host cell displays repressed or no uracil DNA glycosylase activity. This may be achieved by removal of the host cell ung gene. Use of host cells in the manufacture of pyrimidine deoxyribonucleotides e. g.

Methods And Compositions For Reducing The Environmental Impact Of Animal Waste

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US Patent:
20180326020, Nov 15, 2018
Filed:
Jul 23, 2018
Appl. No.:
16/042841
Inventors:
- GREENFIELD IN, US
Sergey PODKOVYROV - Gaithersburg MD, US
Yuefang HUANG - Highland MD, US
Kurt SCHUSTER - Salisbury MD, US
Jon Edward FERREL - Frankfort IN, US
International Classification:
A61K 38/46
A23K 20/189
C12N 9/16
A23K 50/60
A23K 50/30
A23K 50/75
Abstract:
Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an enzyme, such as alkaline phosphatase, that is effective to reduce the amount of a detrimental compound, such as ammonia or phosphorous, that is present in or released from animal waste. Also provided is a method for increasing phosphorus digestion in an animal. Compositions suitable for use in such methods are also described.

Methods And Compositions For Reducing The Environmental Impact Of Animal Waste

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US Patent:
20160235823, Aug 18, 2016
Filed:
Apr 29, 2016
Appl. No.:
15/142745
Inventors:
- Indianapolis IN, US
Sergey PODKOVYROV - Gaithersburg MD, US
Yuefang HUANG - Highland MD, US
Kurt SCHUSTER - Salisbury MD, US
Jon Edward FERREL - Frankfort IN, US
International Classification:
A61K 38/46
A23K 50/30
A23K 50/75
A23K 20/189
A23K 50/60
Abstract:
Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an enzyme, such as alkaline phosphatase, that is effective to reduce the amount of a detrimental compound, such as ammonia or phosphorous, that is present in or released from animal waste. Also provided is a method for increasing phosphorus digestion in an animal. Compositions suitable for use in such methods are also described.

Methods And Compositions For Reducing The Environmental Impact Of Animal Waste

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US Patent:
20140369989, Dec 18, 2014
Filed:
Feb 7, 2013
Appl. No.:
14/347705
Inventors:
- Indianapolis IN, US
Sergey Podkovyrov - Gaithersburg MD, US
Yuefang Huang - Highland MD, US
Kurt Schuster - Salisbury MD, US
Jon Edward Ferrel - Frankfort IN, US
International Classification:
A23K 1/165
C12N 9/16
US Classification:
424 946
Abstract:
Methods for reducing the environmental impact of animal waste are described. In particular embodiments, the methods comprise administering to an animal an enzyme, such as alkaline phosphatase, that is effective to reduce the amount of a detrimental compound, such as ammonia or phosphorous, that is present in or released from animal waste. Also provided is a method for increasing phosphorus digestion in an animal. Compositions suitable for use in such methods are also described.
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Sergey M Podkovyrov from North Potomac, MDDeceased Get Report