Inventors:
Sean M. Mellican - Gurnee IL, US
Cathie L. Linton - Waukegan IL, US
Jianzhang Mei - Lake Forest IL, US
Jason S. Tedrow - Santa Monica CA, US
Nahathai Charukamnoetkanok - Pittsburgh PA, US
Rodger Henry - Wildwood IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C07D 495/04
A61K 31/519
A61P 35/04
A61P 35/02
A61P 17/06
A61P 9/12
Abstract:
A crystalline N-(4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl)-N′-(2-fluoro-5-(trifluoromethyl)phenyl)urea benzenesulfonate characterized in the triclinic crystal system and P-1 space group, when measured with radiation at 0. 7107 Å, by lattice parameters a, b and c of 7. 800 Å0. 001 Å, 13. 406 Å0. 002 Å and 13. 554 Å0. 002 Å, respectively and α, β and γ of 67. 1550. 002, 79. 7240. 002 and 84. 0670. 002, respectively, ways to make it, compositions comprising it, and methods of treatment using it are disclosed.