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Richard P Woychik

from Chapel Hill, NC
Age ~71

Richard Woychik Phones & Addresses

  • 221 Mill Race Dr, Chapel Hill, NC 27514 (919) 961-5633
  • 701 State Highway 3, Bar Harbor, ME 04609 (207) 288-2236
  • 17 Strawberry Hill Rd, Bar Harbor, ME 04609 (207) 288-2236
  • 107 Bates Ct, Orinda, CA 94563 (925) 253-0919
  • Knoxville, TN
  • Boston, MA
  • Cleveland, OH
  • Morris Plains, NJ

Business Records

Name / Title
Company / Classification
Phones & Addresses
Richard Woychik
Manager
Solexa, Inc
Mfg Lab Apparatus/Furniture · Laboratory Apparatus and Furniture Manufacturing
25861 Industrial Blvd, Hayward, CA 94545
(510) 670-9300
Richard P. Woychik
President, Chief Executive Officer, Director
The Jackson Laboratory
Biotechnology · Noncommercial Research Organization · Research & Development in Biotechnology
600 Main St, Bar Harbor, ME 04609
610 Main St, Bar Harbor, ME 04609
(207) 288-6051, (207) 288-6000, (207) 288-6079, (207) 288-6236

Publications

Us Patents

Agouti Polynucleotide Compositions And Methods Of Use

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US Patent:
6514747, Feb 4, 2003
Filed:
Feb 12, 2001
Appl. No.:
09/781811
Inventors:
Richard P. Woychik - Orinda CA
Scott J. Bultman - Lakewood OH
Edward J. Michaud - Kingston TN
Assignee:
UT-Battelle, LLC - Oak Ridge TN
International Classification:
C12N 121
US Classification:
4352523, 435325, 4353201, 43525411, 536 231, 536 235, 536 2433
Abstract:
Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.

Allelic Series Of Genomic Modifications In Cells

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US Patent:
6835867, Dec 28, 2004
Filed:
Jun 24, 1998
Appl. No.:
09/103846
Inventors:
Richard P. Woychik - Orinda CA, 94563
Terry R. Magnuson - Chapel Hill NC, 27514
Ellis D. Avner - Beachwood OH, 44122
James W. Thomas - Rockville MD, 20851
International Classification:
C12N 1500
US Classification:
800 21, 800 8, 800 14, 800 18, 800 20, 800 22, 435441, 435442, 435443, 435444, 435445, 435446, 435447, 435448, 435455, 435462, 435463, 435325
Abstract:
The present invention relates to methods of producing an allelic series of modifications in genes of interest in a cell. In particular, the invention provides methods for using nucleic acid sequence-modifying agents (e. g. , chemicals, electromagnetic radiation, etc. ) to introduce modifications in any nucleic acid sequence in the genome of a cell. Also provided are sets of cells which contain at least one modification in any gene of interest. The methods and compositions of the invention are useful in determining the function of the gene of interest.

Isolation And Characterization Of Agouti: A Diabetes/Obesity Related Gene

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US Patent:
57896518, Aug 4, 1998
Filed:
Jun 5, 1995
Appl. No.:
8/465293
Inventors:
Richard P. Woychik - Knoxville TN
Assignee:
Martin Marietta Energy Systems, Inc. - Oak Ridge TN
International Classification:
C12N 500
C12N 1500
C12N 1509
C12N 1563
US Classification:
800 2
Abstract:
The present invention relates to the cloning and expression of the Agouti gene and analogous genes in transformed, transfected and transgenic mice. The present invention provides an animal model for the study of diabetes, obesity and tumors for the testing of potential therapeutic agents. The present invention provides oligonucleotide probes for the detection of the Agouti gene and mutations in the gene. The present invention also relates to the isolation and recombinant production of the Agouti gene product, production of antibodies to the Agouti gene product and their use as diagnostic and therapeutic agents.

Use Of A Bgh Gdna Polyadenylation Signal In Expression Of Non-Bgh Polypeptides In Higher Eukaryotic Cells

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US Patent:
51224585, Jun 16, 1992
Filed:
Jan 11, 1989
Appl. No.:
7/295967
Inventors:
Leonard E. Post - Kalamazoo MI
Daniel P. Palermo - Kalamazoo MI
Darrell R. Thomsen - Kalamazoo MI
Fritz M. Rottman - Pepper Pike OH
Edward C. Goodwin - Cleveland Heights OH
Richard P. Woychik - Knoxville TN
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12N 1511
C12N 1512
C12N 1585
C12P 2100
US Classification:
435 691
Abstract:
The present invention relates to the use of the polyadenylation signal from the gene for bovine growth hormone to achieve a high level of expression of peptides in eukaryotic cells. Accordingly, the present invention provides a recombinant DNA compound comprising: a first nucleotide sequence which contains a promoter capable of initiating transcription of a gene; a second nucleotide sequence which encodes a gene for a polypeptide other than bovine growth hormone, including genomic and other intron containing forms thereof; a third nucleotide sequence which contains a bovine growth hormone polyadenylation signal; and a fourth nucleotide sequence which optionally contains a selectable marker. The first, second and third sequences are operably linked in sequence to form a functional genetic unit capable of being expressed. The fourth sequence, which is optionally provided, is useful for determining whether or not the DNA of the present invention has been incorporated into a living cell.

Isolation And Characterization Of Agouti: A Diabetes/Obesity Related Gene

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US Patent:
58436529, Dec 1, 1998
Filed:
Jun 5, 1995
Appl. No.:
8/463387
Inventors:
Richard P. Woychik - Knoxville TN
Assignee:
Lockheed Martin Energy Systems, Inc. - Oak Ridge TN
International Classification:
C12Q 168
C12P 1934
C07H 2102
C07H 2104
US Classification:
435 6
Abstract:
The present invention relates to the cloning and expression of the Agouti gene and analogous genes in transformed, transfected and transgenic mice. The present invention provides an animal model for the study of diabetes, obesity and tumors for the testing of potential therapeutic agents. The present invention provides oligonucleotide probes for the detection of the Agouti gene and mutations in the gene. The present invention also relates to the isolation and recombinant production of the Agouti gene product, production of antibodies to the Agouti gene product and their use as diagnostic and therapeutic agents.

Isolation And Characterization Of Agouti: A Diabetes/Obesity Related Gene

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US Patent:
60805501, Jun 27, 2000
Filed:
Jun 22, 1998
Appl. No.:
9/102977
Inventors:
Richard P. Woychik - Knoxville TN
Assignee:
Lockheed Martin Energy Research Corp. - Oak Ridge TN
International Classification:
G01N 33567
US Classification:
435 721
Abstract:
The present invention relates to the cloning and expression of the Agouti gene and analogous genes in transformed, transfected and transgenic mice. The present invention provides an animal model for the study of diabetes, obesity and tumors for the testing of potential therapeutic agents. The present invention provides oligonucleotide probes for the detection of the Agouti gene and mutations in the gene. The present invention also relates to the isolation and recombinant production of the Agouti gene product, production of antibodies to the Agouti gene product and their use as diagnostic and therapeutic agents.

Agouti Polypeptide Compositions

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US Patent:
63100347, Oct 30, 2001
Filed:
Mar 3, 1998
Appl. No.:
9/034088
Inventors:
Richard P. Woychik - Orinda CA
Scott J. Bultman - Lakewood OH
Edward J. Michaud - Kingston TN
Assignee:
UT-Battelle, LLC - Oak Ridge TN
International Classification:
C07K 14435
US Classification:
514 2
Abstract:
Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.
Richard P Woychik from Chapel Hill, NC, age ~71 Get Report