US Patent:
20130149251, Jun 13, 2013
Inventors:
Scott A. Hilderbrand - Swampscott MA, US
Ralph Weissleder - Peabody MA, US
Peter Panizzi - Auburn AL, US
Jason R. McCarthy - Townsend MA, US
Assignee:
THE GENERAL HOSPITAL CORPORATION - Boston MA
International Classification:
A61K 49/00
US Classification:
424 96, 544 37, 435 29, 544 99
Abstract:
The present invention provides methods and compositions based on optical sensor conjugates that are useful for detecting reactive oxygen, reactive nitrogen, or both species that are a direct result of inflammation caused by tissue damage.