Peter T Meinke

6399786, Jun 4, 2002

Jul 9, 2001

09/901264

Steven L. Colletti - Princeton Junction NJ
Michael H. Fisher - Ringoes NJ
Peter T. Meinke - Plainfield NJ
Matthew J. Wyvratt - Mountainside NJ

Merck Co., Inc. - Rahway NJ

A61K 31407

548417, 549381, 549414, 549472, 549473, 549 59, 549 60, 514410, 514422, 514423, 514444, 514453, 514461

The present invention relates to novel nodulosporic acid derivatives, which are acaricidal, antiparasitic, insecticidal and anthelmintic agents.

6586452, Jul 1, 2003

Jul 9, 2001

09/901266

Thomas Shih - Jackson NJ
Steven L. Colletti - Princeton Junction NJ
Michael H. Fisher - Ringoes NJ
Peter T. Meinke - Plainfield NJ
Howard C. H. Kuo - South Plainfield NJ
Prasun K. Chakravarty - Edison NJ
Matthew J. Wyvratt - Mountainside NJ
Sriram Tyagarajan - Edison NJ
Richard Berger - Cranford NJ

Merck Co., Inc. - Rahway NJ

C07D48716

514358, 544 92, 544 96, 544142, 544281, 544350, 546 84, 546121, 546174, 546198, 5462767, 548154, 548181, 548216, 548218, 548221, 548231, 548236, 548238, 548247, 5483241, 514374, 514375, 514376, 514365, 514368, 514378, 514392, 514410

The present invention relates to novel nodulosporic acid derivatives, which are acaricidal, antiparasitic, insecticidal and anthelmintic agents.

7186746, Mar 6, 2007

Aug 27, 2003

10/524697

Sheryl D. Debenham - Scotch Plains NJ, US
Kun Liu - Edison NJ, US
Peter T. Meinke - Plainfield NJ, US
Harold B. Wood - Westfield NJ, US
Regina M. Black - Cranford NJ, US

Merck & Co., Inc. - Rahway NJ

A61K 31/40
C07D 209/36

514419, 548484

Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.

7345085, Mar 18, 2008

Mar 6, 2007

11/714341

Sheryl D. Debenham - Scotch Plains NJ, US
Kun Liu - Edison NJ, US
Peter T. Meinke - Plainfield NJ, US
Harold B. Wood - Westfield NJ, US
Regina M. Black - Cranford NJ, US

Merck & Co., Inc. - Rahway NJ

A61K 31/40
C07D 209/36

514419, 548484

Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.

7348348, Mar 25, 2008

Apr 25, 2003

10/512924

Howard C. H. Kuo - Plainfield NJ, US
Michelle B. Ayer - Fanwood NJ, US
Prasun K. Chakravarty - Edison NJ, US
Peter T. Meinke - Plainfield NJ, US
William H. Parsons - Belle Mead NJ, US
Sriram Tyagarajan - Edison NJ, US

Merck & Co. Inc. - Rahway NJ

A61K 31/425
C07D 277/00

514369, 548183

Aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds are sodium channel blockers; pharmaceutical compositions that include an effective amount of the aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds and a pharmaceutically acceptable carrier, and a method of treatment of acute pain, chronic pain, visceral pain, inflammatory pain, or neuropathic pain, as well as initable bowel syndrome, Cnohns disease, epilepsy, partial and generalized tonic seizures, multiple sclerosis, bipolar depression, and tachy-arrhythmias by the administration of an effective amount of aryl-link-aryl thiazolidine-dione and aryl-link-aryl oxazolidine-dione compounds are described.

7393960, Jul 1, 2008

Aug 28, 2003

10/525470

Peter T. Meinke - Plainfield NJ, US
Harold B. Wood - Westfield NJ, US
Regina M. Black - Cranford NJ, US

Merck & Co., Inc. - Rahway NJ

C07D 261/20
A01N 43/80

548241, 514379

Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.

7414067, Aug 19, 2008

Mar 24, 2004

10/542169

Edward Andrew Boyd - Berkshire, GB
Michael H. Fisher - Ringoes NJ, US
Maria L. Garcia - Edison NJ, US
Gregory J. Kaczorowski - Edison NJ, US
Peter T. Meinke - Plainfield NJ, US
William H. Parsons - Belle Mead NJ, US
Stephen Price - Hertford, GB
John Stibbard - Oxon, GB

Merck & Co. Inc. - Rahway NJ
Evotec OAI

A61K 31/427
A61K 31/5377
C07D 277/20
C07D 403/02
C07D 413/02

514371, 548146, 548190, 548193, 548194, 548195, 544106, 544143, 544224, 544358, 544373, 5142312, 5142328, 5142352, 51425213, 514370

This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

7625933, Dec 1, 2009

Jun 28, 2005

11/631465

Kun Liu - Edison NJ, US
Peter T. Meinke - Scotch Plains NJ, US
Harold B. Wood - Westfield NJ, US

Merck & Co., Inc. - Rahway NJ

A61K 31/422
C07D 263/04
C07D 413/10

514376, 548215, 548227, 548250, 548253, 514374, 514381, 514382

Indoles of Formula I having —X-aryl-(CH)-oxazolidinedione and —X-heteroaryl-(CH)x-oxazolidinedione substituents on the N atom of the indole ring, where x is 0 or 1, and —X— is a bond or —CH—, and their thiazolidinedione analogs, are PPAR gamma agonists or partial agonists and are useful in the treatment and control of type II diabetes, including hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.