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Paul A Dimilla

from Laguna Niguel, CA
Age ~61
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Also known as:
Paula Dimilla, Paul A
Phone and address:
31563 Crystal Sands Dr, Laguna Beach, CA 92677
Related to:
Orie E Allen, 83Jermey W Allen, 45
Connected to:
Robert T Dimilla, 57Grant Dimille, 63Lia E Dimillio, 32Jane M Dimillo, 83Rita Dimillo, 70Ryan A Dimillo, 41Sandy Dimillo, 72Sharon Diming, 38Erin E Diminich, 35Crystal L Diminno, 59

Paul Dimilla Phones & Addresses

  • 31563 Crystal Sands Dr, Laguna Niguel, CA 92677
  • Laguna Beach, CA
  • 3103 Orleans Dr, Oxnard, CA 93036 (805) 351-5440
  • 12364 Carmel Country Rd UNIT 304, San Diego, CA 92130 (339) 206-5491
  • Lexington, MA
  • 20 Water St, Wakefield, MA 01880 (781) 246-3594
  • North Andover, MA
  • Reading, MA
  • 12364 Carmel Country Rd UNIT 3, San Diego, CA 92130

Work

Company: Hospira icu medical May 2007 Position: Principal software engineer

Education

Degree: Bachelors, Bachelor of Science School / High School: Merrimack College 1981 to 1985 Specialities: Computer Science

Skills

Java • Software Design • Web Applications • Software Development • Xml • Software Engineering • Agile Methodologies • Object Oriented Design • Web Services • Software Project Management • Subversion • Scrum • Gui • Gui Development • C++ • Requirements Analysis • Software Development Life Cycle • Integration • Sdlc

Industries

Computer Software

Resumes

Resumes

Paul Dimilla Photo 1

Principal Software Engineer

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Location:
Laguna Niguel, CA
Industry:
Computer Software
Work:
Hospira Icu Medical
Principal Software Engineer
Instrumentation Laboratory Dec 2003 - Apr 2007
Senior Software Engineer
Banta Integrated Media Jul 2000 - Mar 2003
Senior Software Engineer
Tasc, Inc. Jan 1989 - Jul 2000
Senior Member of Technical Staff
Textron Systems Jul 1985 - Jan 1989
Engineer Iii
Education:
Merrimack College 1981 - 1985
Bachelors, Bachelor of Science, Computer Science
Skills:
Java
Software Design
Web Applications
Software Development
Xml
Software Engineering
Agile Methodologies
Object Oriented Design
Web Services
Software Project Management
Subversion
Scrum
Gui
Gui Development
C++
Requirements Analysis
Software Development Life Cycle
Integration
Sdlc

Publications

Us Patents

Vivo Induction For Enhanced Function Of Isolated Hepatocytes

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US Patent:
6394812, May 28, 2002
Filed:
Jul 24, 2000
Appl. No.:
09/621921
Inventors:
Susan J. Sullivan - Newton MA
Paul G. Gregory - Shrewsbury MA
Paul A. DiMilla - Dover MA
Assignee:
Organogenesis Inc. - Canton MA
International Classification:
C12N 500
US Classification:
434375, 424 937
Abstract:
The invention features a liver cell culture comprising hepatocytes that have increased detoxification enzyme activity when isolated from a liver of a donor that had been administered at least one induction agent prior isolation of hepatocyte cells. The induced hepatocytes are used in a bioreactor and cultured to produce hepatocyte cell products or metabolize toxins added to the culture. The bioreactor is, or is an integral part of, a liver assist device used to treat a patient in need of liver assist.

Cell Culture Systems And Methods For Organ Assist Devices

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US Patent:
6465252, Oct 15, 2002
Filed:
Jun 21, 2000
Appl. No.:
09/599891
Inventors:
Mehmet Toner - Wellesley MA
Arno W. Tilles - Cambridge MA
Ulysses J. Balis - Peabody MA
Martin L. Yarmush - Newton MA
Maury D. Cosman - Woburn MA
Paul A. Dimilla - Dover MA
Assignee:
The General Hospital Corporation - Boston MA
Organogenesis Inc. - Canton MA
International Classification:
C12N 500
US Classification:
435401, 4352841, 4352971, 4352972, 435402, 435395, 435399
Abstract:
The invention features modular cell culturing devices including one or more flat-plate modules, and is based on the discovery that if the flows of liquid medium and oxygenated fluid are separated by a gas-permeable, liquid-impermeable membrane, and the cells are grown attached to the liquid side of the membrane, the device can be used to culture cells with transport of oxygen through the membrane (i. e. , direct oxygenation), without regard for the flow rate of the liquid medium passing through the device. The new flow-through cell culturing devices can thus be used to culture cells, e. g. , hepatocytes, with high levels of cell function in organ, e. g. , liver, assist systems, for production of cells, for production of cell-derived products, such as, proteins or viruses, or for systems to treat biological liquids to remove toxins, such as, ammonia, or add cell-synthesized products, or both.

In Vivo Induction For Enhanced Function Of Isolated Hepatocytes

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US Patent:
6699716, Mar 2, 2004
Filed:
Dec 21, 2001
Appl. No.:
10/036593
Inventors:
Susan J. Sullivan - Newton MA
Paul G. Gregory - Shrewsbury MA
Paul A. DiMilla - Dover MA
Assignee:
Organogenesis Inc. - Canton MA
International Classification:
C12N 500
US Classification:
435375, 424 937
Abstract:
The invention features a liver cell culture comprising hepatocytes that have increased detoxification enzyme activity when isolated from a liver of a donor that had been administered at least one induction agent prior isolation of hepatocyte cells. The induced hepatocytes are used in a bioreactor and cultured to produce hepatocyte cell products or metabolize toxins added to the culture. The bioreactor is, or is an integral part of, a liver assist device used to treat a patient in need of liver assist.

Cell Culture Systems And Methods For Organ Assist Devices

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US Patent:
6759245, Jul 6, 2004
Filed:
Jun 21, 2000
Appl. No.:
09/599891
Inventors:
Mehmet Toner - Wellesley MA
Arno W. Tilles - Cambridge MA
Ulysses J. Balis - Peabody MA
Martin L. Yarmush - Newton MA
Maury D. Cosman - Woburn MA
Paul A. Dimilla - Dover MA
Assignee:
The General Hospital Corporation - Boston MA
Organogenesis Inc. - Canton MA
International Classification:
C12N 500
US Classification:
435401, 4352841, 4352971, 4352972, 435402, 435395, 435399
Abstract:
The invention features modular cell culturing devices including one or more flat-plate modules, and is based on the discovery that if the flows of liquid medium and oxygenated fluid are separated by a gas-permeable, liquid-impermeable membrane, and the cells are grown attached to the liquid side of the membrane, the device can be used to culture cells with transport of oxygen through the membrane (i. e. , direct oxygenation), without regard for the flow rate of the liquid medium passing through the device. The new flow-through cell culturing devices can thus be used to culture cells, e. g. , hepatocytes, with high levels of cell function in organ, e. g. , liver, assist systems, for production of cells, for production of cell-derived products, such as, proteins or viruses, or for systems to treat biological liquids to remove toxins, such as, ammonia, or add cell-synthesized products, or both.

Chamber With Adjustable Volume For Cell Culture And Organ Assist

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US Patent:
6855542, Feb 15, 2005
Filed:
Dec 19, 2002
Appl. No.:
10/325437
Inventors:
Paul A. DiMilla - Dover MA, US
Maury D. Cosman - Medfield MA, US
Rachel Halych - Quincy MA, US
Lisa Romito - Brookline MA, US
Chris Gemmeti - Atlanta GA, US
Kevin Odlum - Springfield MA, US
Assignee:
Organogenesis Inc. - Canton MA
International Classification:
C12M003/00
US Classification:
4352891, 4353043, 435383, 424 947
Abstract:
The invention features modular chambers for culturing cells in which the volume of a chamber can be adjusted without compromising the seal or sterility of the chamber. The invention is based on the principle that the volume of a chamber formed between two plates sandwiching a compressible gasket and a substantially incompressible stop can be adjusted using a gasket that forms a fluid-tight seal between the plates at a plurality of levels of compression. The invention enables the culture of cells between substantially parallel and rigid plates in which a relatively large volume can be used to seed the cells and the holdup volume reduced for perfusion without opening or otherwise disassembling the system to compromise its liquidtightness and sterility. The new closed, modular and scalable cell-culturing chamber can be thus perfused and used to culture cells (e. g. , hepatocytes) with high levels of cell function in organ (e. g.

In Vivo Induction For Enhanced Function Of Isolated Hepatocytes

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US Patent:
7169607, Jan 30, 2007
Filed:
Jun 27, 2003
Appl. No.:
10/607695
Inventors:
Susan J. Sullivan - Newton MA, US
Paul G. Gregory - Shrewsbury MA, US
Paul A. DiMilla - Dover MA, US
Assignee:
Organogenesis, Inc - Canton MA
International Classification:
C12N 5/00
US Classification:
435375, 424 937, 4352891
Abstract:
The invention features a liver cell culture comprising hepatocytes that have increased detoxification enzyme activity when isolated from a liver of a donor that had been administered at least one induction agent prior isolation of hepatocyte cells. The induced hepatocytes are used in a bioreactor and cultured to produce hepatocyte cell products or metabolize toxins added to the culture. The bioreactor is, or is an integral part of, a liver assist device used to treat a patient in need of liver assist.

Chamber With Adjustable Volume For Cell Culture And Organ Assist

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US Patent:
7348176, Mar 25, 2008
Filed:
Feb 14, 2005
Appl. No.:
11/057772
Inventors:
Paul A. DiMilla - Dover MA, US
Maury D. Cosman - Medfield MA, US
Rachel Halych - Quincy MA, US
Lisa Romito - Brookline MA, US
Chris Gemmeti - Atlanta GA, US
Kevin Odlum - Springfield MA, US
Assignee:
Organogenesis, Inc. - Canton MA
International Classification:
C12M 3/00
US Classification:
4352891, 4353043, 435383, 424 947
Abstract:
The invention features modular chambers for culturing cells in which the volume of a chamber can be adjusted without compromising the seal or sterility of the chamber. The invention is based on the principle that the volume of a chamber formed between two plates sandwiching a compressible gasket and a substantially incompressible stop can be adjusted using a gasket that forms a fluid-tight seal between the plates at a plurality of levels of compression. The invention enables the culture of cells between substantially parallel and rigid plates in which a relatively large volume can be used to seed the cells and the holdup volume reduced for perfusion without opening or otherwise disassembling the system to compromise its liquidtightness and sterility. The new closed, modular and scalable cell-culturing chamber can be thus perfused and used to culture cells (e. g. , hepatocytes) with high levels of cell function in organ (e. g.

Cell Culture Systems And Methods For Organ Assist Devices

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US Patent:
20030017142, Jan 23, 2003
Filed:
Jul 15, 2002
Appl. No.:
10/196653
Inventors:
Mehmet Toner - Wellesley MA, US
Arno Tilles - Cambridge MA, US
Ulysses Balis - Peabody MA, US
Martin Yarmush - Newton MA, US
Maury Cosman - Woburn MA, US
Paul Dimilla - Dover MA, US
Assignee:
The General Hospital Corporation, a Massachusetts corporation
International Classification:
A61K045/00
C12N005/08
US Classification:
424/093700, 435/370000
Abstract:
The invention features-modular cell culturing devices including one or more flat-plate modules, and is based on the discovery that if the flows of liquid medium and oxygenated fluid are separated by a gas-permeable, liquid-impermeable membrane, and the cells are grown attached to the liquid side of the membrane, the device can be used to culture cells with transport of oxygen through the membrane (i.e., direct oxygenation), without regard for the flow rate of the liquid medium passing through the device. The new flow-through cell culturing devices can thus be used to culture cells, e.g., hepatocytes, with high levels of cell function in organ, e.g., liver, assist systems, for production of cells, for production of cell-derived products, such as, proteins or viruses, or for systems to treat biological liquids to remove toxins, such as, ammonia, or add cell-synthesized products, or both.
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Paul A Dimilla from Laguna Niguel, CA, age ~61 Get Report