Inventors:
Gregory M Cruise - Fremont CA
Olexander Hnojewyj - Saratoga CA
Assignee:
NeoMend, Inc. - Sunnyvale CA
International Classification:
A61B 1708
Abstract:
A biocompatible and biodegradable barrier material is applied to a tissue region, e. g. , to seal a vascular puncture site. The barrier material comprises a compound, which is chemically cross-linked without use of an enzyme to form a non-liquid mechanical matrix. The compound preferably includes a protein comprising recombinant or natural serum albumin, which is mixed with a polymer that comprises poly(ethylene) glycol (PEG), and, most preferably, a multi-armed PEG polymer.