Resumes
Resumes
Oksana Yakovleva Phones & Addresses
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15933 Yukon Ln, Derwood, MD 20855 (301) 987-8754
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Rockville, MD
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Gaithersburg, MD
Publications
Us Patents
Inhibition Of Prion Protein Propagation By Receptor Associated Protein (Rap), Its Derivatives, Mimetics And Synthetic Peptides
View pageUS Patent:
20120135936, May 31, 2012
Filed:
May 17, 2010
Appl. No.:
13/265242
Inventors:
Larisa Cervenakova - Rockville MD, US
Oksana Yakovleva - Derwood MD, US
Oksana Yakovleva - Derwood MD, US
Assignee:
AMERICAN NATIONAL RED CROSS - WASHINGTON DC
International Classification:
A61K 38/17
A61P 25/28
A61P 25/28
US Classification:
514 177
Abstract:
A pharmaceutical formulation and method of treatment of prion disease include a RAP agent with a pharmaceutically acceptable carrier and/or excipient, and the administration of same to a subject suffering from or at risk of a prion disease. The RAP agent is an effective means for the prevention and/or treatment of various prion diseases regardless whether the disease is acquired by infection or by genetic mutation.
Method For Identifying Ligands Specific For Structural Isoforms Of Proteins
View pageUS Patent:
20050032138, Feb 10, 2005
Filed:
Apr 14, 2004
Appl. No.:
10/823888
Inventors:
Julia Lathrop - Falls Church VA, US
David Hammond - Laytonsville MD, US
Larisa Cervenakova - Rockville MD, US
Liliana Gheorghiu - Cambridge MA, US
Oksana Yakovleva - Derwood MD, US
David Hammond - Laytonsville MD, US
Larisa Cervenakova - Rockville MD, US
Liliana Gheorghiu - Cambridge MA, US
Oksana Yakovleva - Derwood MD, US
International Classification:
G01N033/53
G01N033/537
G01N033/543
G01N033/537
G01N033/543
US Classification:
435007920
Abstract:
A method of identifying a ligand specific for a structural isoform of a protein by the binding of the structural isoform to a ligand on a support, a direct positional transfer of the structural isoform and a control isoform between two or more different solid or semi-solid supports and detection of at least one of the isoforms on each support, thus allowing for subtractive identification techniques to be used to identify the subset of ligands, or a ligand, specific for the structural isoform.