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Nadine A Defranoux

from San Francisco, CA
Age ~60
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Also known as:
Nadine X
Phone and address:
71 Hallam St, San Francisco, CA 94103
(415) 252-1241
Connected to:
Alex Defranzo, 33Tara M Defranza, 35Mary C Defrasia, 57Karen A Defrate, 66Susan Defratus, 60Ronald E Defrece, 57Brian R Defreece, 48Malinda L Defreece, 63Melissa N Defreece, 44Peter F Defreece, 61

Nadine Defranoux Phones & Addresses

  • 71 Hallam St, San Francisco, CA 94103 (415) 252-1241
  • 1227 Cole St, San Francisco, CA 94117 (415) 753-0657
  • 1908 Menalto Ave, Menlo Park, CA 94025 (650) 326-4842

Resumes

Resumes

Nadine Defranoux Photo 1

Program Manager

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Location:
San Francisco, CA
Industry:
Biotechnology
Work:
Crescendo Bioscience since May 2012
Associate Director Scientific Modeling and Collaborations
freelance since Feb 2012
French-English Technical Translator
Emphusion - San Francisco Jul 2011 - Dec 2011
Sr. Clinical Project Manager
Synarc Oct 2007 - Aug 2011
Sr. Clinical Project Manager/Supervisor
Entelos, Inc. Dec 1997 - Mar 2007
Senior Scientist - Project Team Lead
Education:
University of California, San Francisco 1991 - 1997
Université Denis Diderot (Paris VII) 1987 - 1991
Institut Pasteur 1985 - 1986
Université de Nice-Sophia Antipolis 1984 - 1985
College Pierre & Marie Curie 1981 - 1983
San Francisco Photo Center
Skills:
Biotechnology
Immunology
Infectious Diseases
Pharmaceutical Industry
Biomarkers
Rheumatoid Arthritis
Clinical Research
Biochemistry
Life Sciences
Clinical Trials
Molecular Biology
Ctms
Cro
Cross Functional Team Leadership
Systems Biology
Disease
R&D
Edc
Neurology
Clinical Development
Clinical Trial Management
Asthma
Medical Imaging
Technical Project Leadership
Scientific Communications
Alzheimer's Disease
Gcp
Relationship Management
Project Management
Data Analysis
Line Management
Microbiology
Coaching and Mentoring
Photography
Business Development
Budget Management
Rfp
Oncology
English
French
Interests:
Arts and Culture
Languages:
English
French
German
Nadine Defranoux Photo 2

Nadine Defranoux

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Publications

Us Patents

Method And Apparatus For Computer Modeling A Joint

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US Patent:
7472050, Dec 30, 2008
Filed:
Feb 11, 2005
Appl. No.:
11/056952
Inventors:
Nadine A. Defranoux - San Francisco CA, US
Todd B. Dubnicoff - Burlingame CA, US
Annette K. Lewis - Menlo Park CA, US
Thomas S. Paterson - West Hollywood CA, US
Saroja Ramanujan - San Mateo CA, US
Lisl K. M. Shoda - Redwood City CA, US
Karl Petter Soderstrom - San Francisco CA, US
Herbert K. Struemper - Menlo Park CA, US
Assignee:
Entelos, Inc. - Foster City CA
International Classification:
G06G 7/48
US Classification:
703 11, 703 2
Abstract:
The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.

Method And Apparatus For Computer Modeling A Joint

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US Patent:
20030078759, Apr 24, 2003
Filed:
May 22, 2002
Appl. No.:
10/154123
Inventors:
Nadine Defranoux - San Francisco CA, US
Todd Dubnicoff - Burlingame CA, US
David Klinke - San Bruno CA, US
Annette Lewis - Menlo Park CA, US
Thomas Paterson - West Hollywood CA, US
Saroja Ramanujan - San Mateo CA, US
Lisl Shoda - Redwood City CA, US
Karl Soderstrom - San Francisco CA, US
Herbert Struemper - Menlo Park CA, US
International Classification:
G06G007/48
US Classification:
703/011000
Abstract:
The present invention relates to a mathematical and computer model of a joint. The model includes representation of the biological processes related to the synovial tissue and cartilage. In one embodiment, the model represents a human joint afflicted with rheumatoid arthritis.

Treatment Of Rheumatoid Arthritis With Hypoxia Inducible Factor-1Alpha Antagonists

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US Patent:
20050148496, Jul 7, 2005
Filed:
Nov 24, 2004
Appl. No.:
10/997764
Inventors:
Nadine Defranoux - San Francisco CA, US
Vincent Hurez - Albany CA, US
Seth Michelson - San Jose CA, US
Lisl Shoda - Menlo Park CA, US
Leif Wennerberg - Mountain View CA, US
Assignee:
Entelos, Inc. - Foster City CA
International Classification:
A61K038/17
A61K048/00
US Classification:
514002000, 514044000
Abstract:
The invention encompasses a novel method of treating inflammatory disease, such as rheumatoid arthritis, and novel methods of identifying and screening for drugs useful in the treatment of inflammatory diseases and their clinical symptoms. The inventors have made the discovery that the activity of HIF-1α, a transcription regulator known to have an effect on some cancers, has a significant impact on the pathophysiology of rheumatoid arthritis. The symptoms of an inflammatory disease, such as rheumatoid arthritis, may be alleviated by administering a compound that inhibits the activity of HIF-1α.

Treatment Of Rheumatoid Arthritis With Flip Antagonists

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US Patent:
20050208151, Sep 22, 2005
Filed:
Nov 1, 2004
Appl. No.:
10/980145
Inventors:
Vincent Hurez - Albany CA, US
Saroja Ramanujan - Daly City CA, US
Lisl Shoda - Menlo Park CA, US
Leif Wennerberg - Mountain View CA, US
Seth Michelson - San Jose CA, US
Nadine Defranoux - San Francisco CA, US
Assignee:
Entelos, Inc. - Foster City CA
International Classification:
A61K038/17
A61K048/00
A61K031/277
A61K031/7072
A61K031/704
A61K031/407
A61K031/16
A61K033/24
A61K031/19
US Classification:
424649000, 514012000, 514044000, 514034000, 514521000, 514049000, 514557000, 514410000, 514615000
Abstract:
The invention encompasses novel methods of treating rheumatoid arthritis and its symptoms and novel methods of identifying and screening for drugs useful in the treatment of rheumatoid arthritis and its clinical symptoms. Targeted manipulation of a computer model of a human rheumatic joint provided the surprising result that decreasing the activity of FLIP, an inhibitor of apoptosis, by at least 25% has a significant impact on the pathophysiology of rheumatoid arthritis. Inhibition of the activity of FLIP by at least 25% is predicted to alleviate the symptoms of rheumatoid arthritis.
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Nadine A Defranoux from San Francisco, CA, age ~60 Get Report