Search

Michael A Mauragis

from Scotts, MI
Age ~68
Get Report
Also known as:
Michael S
Phone and address:
9337 Arrowhead Dr, Scotts, MI 49088
(269) 327-6578
Related to:
Velda V Jones, 91Perry Piccard, 61Frank MauragisTodd P Perry, 61Jane E Piccard, 62Erik Piccard, 31
Connected to:
Bruce Mauraides, 74Jason R Maurais, 42Yves C Maurais, 64Jonathan B Maurakis, 52Bryan Maurantonio, 68Brenda E Maurao, 50Jasmine M Mauras, 33Winifred A Mauras, 78Katherine L Maurath, 40Lisa A Maurath, 42

Michael Mauragis Phones & Addresses

  • 9337 Arrowhead Dr, Scotts, MI 49088 (269) 327-6578
  • Portage, MI
  • East Nassau, NY

Work

Position: Homemaker

Education

School / High School: Northeastern University

Industries

Pharmaceuticals

Resumes

Resumes

Michael Mauragis Photo 1

Michael Mauragis

View page
Location:
Kalamazoo, MI
Industry:
Pharmaceuticals
Education:
Northeastern University

Publications

Us Patents

Process For Preparing Indolinone Derivatives

View page
US Patent:
7119209, Oct 10, 2006
Filed:
Feb 14, 2003
Appl. No.:
10/367008
Inventors:
Qingwu Jin - Kalamazoo MI, US
Michael A. Mauragis - Scotts MI, US
Paul D. May - Kalamazoo MI, US
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07D 417/06
C07D 249/08
C07D 403/02
C07D 209/04
US Classification:
548181, 548236, 5482662, 5483121, 548468
Abstract:
The present invention refers to a process for preparing indolinone derivatives of the general formula (VI) as defined in the specification and intermediates of that process.

3-(4-Amidopyrrol-2-Ylmethlidene)-2-Indolinone Derivatives As Protein Kinase Inhibitors

View page
US Patent:
7179910, Feb 20, 2007
Filed:
Sep 8, 2003
Appl. No.:
10/656907
Inventors:
Huiping Guan - Foster City CA, US
Congxin Liang - Sunnyvale CA, US
Li Sun - Foster City CA, US
Peng Cho Tang - Moraga CA, US
Chung Chen Wei - Foster City CA, US
Tomas Vojkovsky - San Mateo CA, US
Qingwu (Alan) Jin - Kalamazoo MI, US
Paul M. Herrinton - Kalamazoo MI, US
Michael A. Mauragis - Scotts MI, US
Assignee:
Agouron Pharmaceuticals, Inc. - San Diego CA
International Classification:
C07D 279/12
C07D 413/14
C07D 209/34
C07D 249/02
C07D 257/04
C07D 403/14
US Classification:
544 582, 544144, 546117, 548468, 548255, 548253, 5483121
Abstract:
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Salts And Polymorphs Of A Pyrrole-Substituted Indolinone Compound

View page
US Patent:
7247627, Jul 24, 2007
Filed:
Sep 30, 2004
Appl. No.:
10/956420
Inventors:
Andrei Blasko - San Bruno CA, US
Qingwu Jin - Palo Alto CA, US
Qun Lu - Portage MI, US
Michael A. Mauragis - Scotts MI, US
Dian Song - Redwood City CA, US
Brenda S. Vonderwell - Plainwell MI, US
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
A61K 31/5377
C07D 413/14
US Classification:
5142352, 544106, 544111, 544141, 544144, 5142312, 5142328, 5142335
Abstract:
The invention relates to non-hygroscopic salts of 5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide, such as maleate salts, and to crystalline polymorphs of these salts. The invention further relates to pharmaceutical compositions of 5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide salts, and methods of treating disorders such as cancer using such compositions.

3-(4-Amidopyrrol-2-Ylmethylidene)-2-Indolinone Der Derivatives As Protein Kinase Inhibitors

View page
US Patent:
7256189, Aug 14, 2007
Filed:
Aug 28, 2006
Appl. No.:
11/511981
Inventors:
Huiping Guan - Foster City CA, US
Congxin Liang - Sunnyvale CA, US
Li Sun - Foster City CA, US
Peng Cho Tang - Moraga CA, US
Chung Chen Wei - Foster City CA, US
Tomas Vojkovsky - San Mateo CA, US
Qingwu (Alan) Jin - Kalamazoo MI, US
Paul M. Herrinton - Kalamazoo MI, US
Michael A. Mauragis - Scotts MI, US
Assignee:
Sugen, Inc. - New York NY
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
A61K 31/5377
C07D 413/14
US Classification:
5142352, 544144
Abstract:
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-(4-Amidopyrrol-2-Ylmethylidene)-2-Indolinone Derivatives As Protein Kinase Inhibitors

View page
US Patent:
7582756, Sep 1, 2009
Filed:
Jul 18, 2007
Appl. No.:
11/779807
Inventors:
Huiping Guan - South San Francisco CA, US
Congxin Liang - Sunnyvale CA, US
Li Sun - Foster City CA, US
Peng Cho Tang - Moraga CA, US
Chung Chen Wei - Foster City CA, US
Tomas Vojkovsky - San Mateo CA, US
Qingwu Jin - Kalamazoo MI, US
Paul M. Herrinton - Kalamazoo MI, US
Michael A. Mauragis - Scotts MI, US
Assignee:
Sugen, Inc. - New York NY
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07D 413/14
US Classification:
544144
Abstract:
The present invention provides a method to make a pyrrole substituted 2-indolinone compound of the formula.

3-(4-Amidopyrrol-2-Ylmethylidene)-2-Indolinone Derivatives As Portein Kinase Inhibitors

View page
US Patent:
20030092917, May 15, 2003
Filed:
Feb 15, 2002
Appl. No.:
10/076140
Inventors:
Huiping Guan - South San Francisco CA, US
Congxin Liang - Sunnyvale CA, US
Li Sun - Foster City CA, US
Peng Tang - Moraga CA, US
Chung Wei - Foster City CA, US
Tomas Vojkovsky - San Mateo CA, US
Qingwu Jin - Kalamazoo MI, US
Paul Herrinton - Kalamazoo MI, US
Michael Mauragis - Scotts MI, US
Assignee:
SUGEN, INC.
International Classification:
C 07D 4 3/02
C 07D 4 3/14
US Classification:
548/468000
Abstract:
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Process For Preparing Indolinone Derivatives

View page
US Patent:
20050171357, Aug 4, 2005
Filed:
Mar 30, 2005
Appl. No.:
11/095433
Inventors:
Qingwu Jin - Kalamazoo MI, US
Michael Mauragis - Scotts MI, US
Paul May - Kalamazoo MI, US
International Classification:
C07D417/02
C07D413/02
C07D043/02
US Classification:
548181000, 548229000, 548311100, 548465000
Abstract:
The present invention refers to a process for preparing indolinone derivatives of the general formula (VI) as defined in the specification and intermediates of that process.
Control profile
Michael A Mauragis from Scotts, MI, age ~68 Get Report