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Martin J Pentony

from Burlington, MA
Age ~59
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Also known as:
Martin Pentoney, Entoni P Martin
Phone and address:
1 High Pine Ave, Burlington, MA 01803
Connected to:
Deidere A Pentony, 55Paul E Pentony, 89John J Pentore, 43Vito Pentrelli, 84Allison R Penttila, 58Eric W Penttinen, 54Erica L Penttila, 45James D Penturelli, 67Eugene A Pentya, 63Srinivas N Pentyala, 59

Martin Pentony Phones & Addresses

  • 1 High Pine Ave, Burlington, MA 01803
  • Bedford, MA
  • 10208 California Ave SW, Seattle, WA 98146
  • Sunnyvale, CA
  • Kiona, WA

Work

Company: Amgen - Seattle, WA Dec 2003 Position: Senior associate scientist

Education

School / High School: University College Cork- Cork 1992 Specialities: Master of Science in Microbiology Department

Industries

Biotechnology

Resumes

Resumes

Martin Pentony Photo 1

Scientist

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Location:
Seattle, WA
Industry:
Biotechnology
Work:
Amgen since Dec 2003
Chief Bottle Washer
Seattle Biomedical Research Institute Dec 2000 - Dec 2003
Baron
Stanford University Jul 1995 - Nov 2000
Top slave
University College Cork Feb 1990 - Dec 1995
slave #3
Education:
University College Cork 1992 - 1993
Msc, Microbiology St. Patrick's College, Maynooth 1985 - 1989
B.Sc., Biology Chemistry
Martin Pentony Photo 2

Martin Pentony Seattle, WA

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Work:
Amgen
Seattle, WA
Dec 2003 to Oct 2014
Senior Associate Scientist
Seattle Biomedical Research Institute
Seattle, WA
2000 to Mar 2003
DNA Core Facility Manger
Protein and Nucleic Acid Facility

1997 to 2000
Life Science Research Assistant II
Protein and Nucleic Acid Facility
Stanford, CA
1995 to 1997
Life Science Research Assistant I
Education:
University College Cork
Cork
1992
Master of Science in Microbiology Department
St Patrick's College
1989
Masters in biology and chemistry

Publications

Us Patents

Method For Making Antibody Fc-Heterodimeric Molecules Using Electrostatic Steering Effects

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US Patent:
20100286374, Nov 11, 2010
Filed:
Jan 6, 2009
Appl. No.:
12/811207
Inventors:
Gunasekaran Kannan - Issaquah WA, US
Michael Wittekind - Bainbridge Island WA, US
Wei Yan - Sammamish WA, US
Martin Pentony - Seattle WA, US
International Classification:
C07K 16/00
C12P 21/06
C12N 5/10
C12N 15/63
C07H 21/04
US Classification:
5303873, 435 691, 435 696, 435325, 4353201, 536 2353
Abstract:
The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer. Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to pharmaceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.

Host Cell For Making Antibody Fc-Heterodimeric Molecules Using Electrostatic Steering Effects

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US Patent:
20140024111, Jan 23, 2014
Filed:
Sep 25, 2013
Appl. No.:
14/037040
Inventors:
Michael WITTEKIND - New Canaan CT, US
Wei YAN - Sammamish WA, US
Martin J. PENTONY - Seattle WA, US
Assignee:
AMGEN INC. - THOUSAND OAKS CA
International Classification:
C07K 16/00
US Classification:
435328
Abstract:
The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to pharmaceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.

Heterodimeric Bispecific Antibodies

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US Patent:
20230077648, Mar 16, 2023
Filed:
Apr 18, 2022
Appl. No.:
17/722724
Inventors:
- Thousand Oaks CA, US
Martin J. Pentony - Seattle WA, US
Luis G. Borges - Redwood City CA, US
Mark L. Michaels - Encino CA, US
International Classification:
C07K 16/46
C07K 16/30
C07K 16/28
C07K 16/32
Abstract:
Provided herein are heterodimeric bispecific antibodies that can mediate cytolysis of a target cell by an immune effector cell, nucleic acids encoding such antibodies, methods of making such antibodies, and methods of using such antibodies. These antibodies comprise two different polypeptide chains, each comprising two immunoglobulin variable regions and, optionally, a half life-extending moiety.

Mixtures Of Antibodies

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US Patent:
20190248899, Aug 15, 2019
Filed:
May 5, 2017
Appl. No.:
16/303611
Inventors:
- Bothell WA, US
Zhi Liu - Shoreline WA, US
Martin J. Pentony - Bedford MA, US
International Classification:
C07K 16/28
C07K 16/32
A61P 35/00
A61K 9/00
Abstract:
Described herein are antibodies and mixtures of antibodies optionally produced by a host cell line, nucleic acids encoding the antibodies and mixtures of antibodies, host cells containing such nucleic acids, and methods of treatment using the antibodies, mixtures of antibodies, or nucleic acids encoding the antibodies or mixtures of antibodies. Also described are methods of producing mixtures of antibodies in host cells.

Protease-Activatable Bispecific Proteins

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US Patent:
20170247476, Aug 31, 2017
Filed:
Sep 24, 2015
Appl. No.:
15/513011
Inventors:
- Thousand Oaks CA, US
Martin J. Pentony - Seattle WA, US
Mark L. Michaels - Encino CA, US
Patrick Baeuerle - Gauting, DE
International Classification:
C07K 16/46
C07K 16/28
C07K 16/32
C07K 14/725
Abstract:
Described herein are protease-activatable proteins (PABPs), which, when activated, can mediate cytolysis of target cells by effector cells. Also provided are nucleic acids encoding such PABPs and methods of making and using PABPs.

Heterodimeric Bispecific Antibodies

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US Patent:
20160115241, Apr 28, 2016
Filed:
Mar 13, 2014
Appl. No.:
14/774320
Inventors:
- Thousand Oaks CA, US
Martin J. Pentony - Seattle WA, US
Luis G. Borges - Bainbridge Island WA, US
Mark L. Michaels - Encino CA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
C07K 16/30
C07K 16/28
Abstract:
Provided herein are heterodimeric bispecific antibodies that can mediate cytolysis of a target cell by an immune effector cell, nucleic acids encoding such antibodies, methods of making such antibodies, and methods of using such antibodies. These antibodies comprise two different polypeptide chains, each comprising two immunoglobulin variable regions and, optionally, a half life-extending moiety.

Heterodimeric Bispecific Antibodies

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US Patent:
20140308285, Oct 16, 2014
Filed:
Mar 12, 2014
Appl. No.:
14/207368
Inventors:
- Thousand Oaks CA, US
Martin J. PENTONY - Seattle WA, US
Luis G. BORGES - Bainbridge Island WA, US
Mark L. MICHAELS - Encino CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07K 16/46
US Classification:
4241361, 5303873, 536 2353, 4353201, 435 696, 43525231, 43525421, 43525233, 43525423, 435328
Abstract:
Provided herein are heterodimeric bispecific antibodies that can mediate cytolysis of a target cell by an immune effector cell, nucleic acids encoding such antibodies, methods of making such antibodies, and methods of using such antibodies. These antibodies comprise two different polypeptide chains, each comprising two immunoglobulin variable regions and, optionally, a half life-extending moiety.
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Martin J Pentony from Burlington, MA, age ~59 Get Report