Laszlo R Treiber

8546436, Oct 1, 2013

Dec 28, 2011

13/339283

Laszlo R. Treiber - San Diego CA, US
Gabriel Galvin - San Diego CA, US
Irina Zamansky - Oceanside CA, US
Jean-Luc Girardet - San Diego CA, US

Ardea Biosciences, Inc. - San Diego CA

A61K 31/41
A61K 31/44
A61K 31/56
C07D 249/00

514383, 514384, 5482622, 5482638

Crystalline polymorph forms of 2-(5-bromo-4-(4-cyclopropyl naphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid are described. Pharmaceutical compositions and the uses of such compounds, compound forms, and compositions for the treatment of a variety of diseases and conditions are also presented.

20120015044, Jan 19, 2012

Jul 11, 2011

13/180485

Laszlo TREIBER - San Diego CA, US
Angela HANSEN - San Diego CA, US

A61K 33/40
A61P 17/00

424616

Disclosed herein are compositions comprising: a pharmaceutically acceptable oxidizing agent; a pharmaceutically acceptable base; and a pharmaceutically acceptable solvent or mixture of solvents. Also disclosed are methods of treating urushiol-induced contact dermatitis in a patient, the method comprising: identifying a patient in need thereof; and administering to the patient a composition as described herein. Further disclosed herein are devices for the treatment of urushiol-induced contact dermatitis, the device comprising: an absorbent material, contained therein a composition as described herein; and means for attaching the device to the skin of a patient in need thereof.

52645932, Nov 23, 1993

Jan 15, 1993

8/006007

Laszlo R. Treiber - Gillette NJ

Merck & Co., Inc. - Rahway NJ

A61K 31335

549363

This invention relates to compounds of structural formula ##STR1## which are inhibitors of squalene synthase and useful as cholesterol lowering agents.

41983386, Apr 15, 1980

Mar 13, 1978

5/885836

Laszlo R. Treiber - Gillette NJ
Vincent P. Gullo - Edison NJ

Merck & Co., Inc. - Rahway NJ

C07D48904
A61K 3140

26032631

Fermentation broths or impure solutions containing thienamycin, a substance having antibiotic activity against gram-negative and gram-positive microorganisms, are purified using a sequence of ion exchange resins, starting with an anion exchange resin of the polystyrene-trimethylammonium type in the HCO. sub. 3 -cycle, and ending with absorption on and elution from a polymeric cross-linked polystyrene-type resin adsorbent. Variations in the intermediate steps, e. g. different resins and eluates are possible and are illustrated within.

51870746, Feb 16, 1993

Feb 20, 1992

7/840601

Laszlo R. Treiber - Gillette NJ
Russell B. Lingham - Watchung NJ
Byron H. Arison - Watchung NJ
Lawrence F. Colwell - Eatontown NJ
Georgette Dezeny - Short Hills NJ
Nancy E. Kohl - Wyndmoor PA

Merck & Co., Inc. - Rahway NJ

C12P 100
C12N 120

435 41

A novel dipeptide isostere is the biotransformed product after incubation with a culture of Streptomyces. It inhibits HIV protease, and is useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as a compound, pharmaceutically acceptable salt, pharmaceutical composition ingredient, whether or not as a prodrug or as a combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

49162390, Apr 10, 1990

Jul 19, 1988

7/221475

Laszlo R. Treiber - Gillette NJ

Merck & Co., Inc. - Rahway NJ

C07D30930

549292

A process for the lactonization of mevinic acid HMG-CoA reductase inhibitors and analogs thereof is disclosed.

53590961, Oct 25, 1994

Nov 20, 1992

7/979559

Laszlo R. Treiber - Gillette NJ
Byron H. Arison - Watchung NJ
George A. Doss - Westfield NJ
Leeyuan Huang - Watchung NJ
John G. MacConnell - Westfield NJ

Merck & Co., Inc. - Rahway NJ

C07D31908

549363

New cholesterol lowering compounds are formed from the photochemical treatment of the zaragozic acids.

61770086, Jan 23, 2001

Nov 12, 1998

9/190503

Laszlo R. Treiber - Chester NJ
Ali Shafiee - Westfield NJ

Merck & Co., Inc. - Rahway NJ

B01D 1508

2101982

There is disclosed a dual compartment solid phase extraction cartridge comprising a container divided into a top volume and a bottom volume by a porous filter or frit, the top and bottom volumes having a quantity of sorbent. The cartridge is useful in the separation of components of a liquid and solid mixture.