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Lara S Shamieh

from Vancouver, WA
Age ~47
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Related to:
Theodore W Utley, 54Shannon Maria Monihan, 56Laila Shamieh, 78Ramzi H Shamieh, 45R ShamiehMusa H Shamieh, 85Ramzi Shamich, 78
Connected to:
Fredric A Shamieh, 91Lois J Shamily, 78Aisha Shamim, 58Asif S Shamim, 34Omid M Shamim, 40Shahnaz Shamim, 79Tabassum Shamim, 61Shaiza Shamin, 47Sofia Shamina, 32Betsy M Shamine, 50

Lara Shamieh Phones & Addresses

  • 210 NW 40Th St, Vancouver, WA 98660
  • Denver, CO
  • Seattle, WA
  • Portland, OR
  • 10103 Nw 27Th Ave, Vancouver, WA 98685

Work

Company: Regis university Jul 2012 to Jul 2015 Position: Assistant professor of biology

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Oregon Health & Science University 2001 to 2005 Specialities: Molecular Biology, Biochemistry

Skills

Biochemistry • Molecular Biology • Cell Culture • Qpcr • Western Blotting • Protein Purification • Cell Biology • Pcr • Tissue Culture • Animal Models • Protein Expression • Immunohistochemistry • Molecular Cloning • Immunofluorescence • Laboratory • Science • Fluorescence Microscopy • Gel Electrophoresis • Confocal Microscopy • Microscopy • Genetics

Industries

Education Management

Resumes

Resumes

Lara Shamieh Photo 1

Lara Shamieh

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Location:
210 northwest 40Th St, Vancouver, WA 98663
Industry:
Education Management
Work:
Regis University Jul 2012 - Jul 2015
Assistant Professor of Biology
University of Washington Jan 2008 - Jun 2012
Senior Research Fellow
University of Washington Oct 2005 - Dec 2007
Post-Doctoral Fellow
Ohsu | Oregon Health & Science University 2000 - 2005
Graduate Research Assistant
Education:
Oregon Health & Science University 2001 - 2005
Doctorates, Doctor of Philosophy, Molecular Biology, Biochemistry Oregon Health and Science University School of Medicine 2001 - 2005
Doctorates, Doctor of Philosophy, Biochemistry University of Portland 1995 - 1999
Bachelors, Bachelor of Science, Biology, Chemistry
Skills:
Biochemistry
Molecular Biology
Cell Culture
Qpcr
Western Blotting
Protein Purification
Cell Biology
Pcr
Tissue Culture
Animal Models
Protein Expression
Immunohistochemistry
Molecular Cloning
Immunofluorescence
Laboratory
Science
Fluorescence Microscopy
Gel Electrophoresis
Confocal Microscopy
Microscopy
Genetics

Publications

Us Patents

Compositions And Methods For Modulating Signaling Mediated By Igf-1 Receptor And Erbb Receptors

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US Patent:
20050272637, Dec 8, 2005
Filed:
Apr 22, 2005
Appl. No.:
11/113202
Inventors:
Gail Clinton - Portland OR, US
Lara Shamieh - Portland OR, US
Assignee:
Oregon Health & Science University - Portland OR
International Classification:
A61K038/17
US Classification:
514002000
Abstract:
The binding interactions between herstatin, or the intron 8-encoded receptor binding domain (RBD Int8) thereof, and several receptors were analyzed. According to aspects of the present invention, herstatin and the intron 8-encoded domain bind with high affinity (e.g., nM concentrations) to all four of the ErbB receptors: EGFR (HER-1, erbB-1); HER-2 (erbB-2); HER-3 (erbB-3); and HER-4 (erbB-4), as well as to ΔEGFR and the IGF-1 receptor, and such binding has utility to modulate signaling mediated by these receptors. Herstatin inhibited target receptor-mediated activation of intracellular signaling pathways ((e.g., PI3/Akt, IRS-2, etc., pathways) that are important in cell survival, and further inhibited target receptor-mediated (e.g., IGF-1/IGF-1R-mediated) survival of cancer cells. Aspects of the present invention thus provide methods and compositions for the treatment of cancer, including cancer refractory to other erbB-based agents, and of other conditions and disorders characterized by target receptor expression, over-expression, signaling, and/or aberrant signaling. Additional aspects provide methods of targeted drug delivery.
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Lara S Shamieh from Vancouver, WA, age ~47 Get Report