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Kishan Rijal

from Lansdale, PA
Age ~50
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Related to:
Pratikshya Rijal, 47
Connected to:
Ananta Rijal, 69Anwesh Rijal, 42Bhawana Rijal, 34Gita Rijal, 50Lila B Rijal, 49Parjanya Rijal, 40Pratikshya T Rijal, 42Sangam Rijal, 37Sudip Rijal, 53Sujan Rijal, 36

Kishan Rijal Phones & Addresses

  • 1493 Maxwell Ct, Lansdale, PA 19446 (267) 644-1088
  • 639 Broad St, Lansdale, PA 19446 (215) 412-3029
  • 113 Manchester Ct, Harleysville, PA 19438
  • 3721 Baring St, Philadelphia, PA 19104 (215) 387-5577
  • Montgomery, PA
  • Ocean City, MD
  • 639 S Broad St APT K2, Lansdale, PA 19446 (215) 412-3029

Work

Company: Sanofi pasteur Mar 2010 Position: Deputy director / spp

Education

Degree: PhD School / High School: Drexel University Specialities: Chemical & Biological Engineering

Skills

Gmp • Validation • Fda • Technology Transfer • Pharmaceutical Industry • Vaccines • Biotechnology • Change Control • Six Sigma • Commercialization • Risk Assessment • Pharmaceutics • Pharmaceuticals • Technical Services • New Technology Implementation • Risk Management • Cleaning Validation

Interests

Training In Pharmaceutical/Biotech

Industries

Pharmaceuticals

Resumes

Resumes

Kishan Rijal Photo 1

Kishan Rijal

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Location:
1493 Maxwell Ct, Lansdale, PA 19446
Industry:
Pharmaceuticals
Work:
Sanofi Pasteur since Mar 2010
Deputy Director / SPP
Merck & Co, Inc. Sep 1999 - Apr 2010
Process Engineer/Manager
Education:
Drexel University
PhD, Chemical & Biological Engineering
Skills:
Gmp
Validation
Fda
Technology Transfer
Pharmaceutical Industry
Vaccines
Biotechnology
Change Control
Six Sigma
Commercialization
Risk Assessment
Pharmaceutics
Pharmaceuticals
Technical Services
New Technology Implementation
Risk Management
Cleaning Validation
Interests:
Training In Pharmaceutical/Biotech

Publications

Us Patents

Controlling Accumulation Of Select Adsorbers On A Piezoelectric Cantilever Sensor

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US Patent:
7935191, May 3, 2011
Filed:
Aug 9, 2007
Appl. No.:
11/836742
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
David R. Maraldo - Gilbertsville PA, US
Kishan Rijal - Harleysville PA, US
Gossett Augustus Campbell - Conshohocken PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
B08B 7/02
G01N 15/06
G01N 29/00
G01N 33/53
G01N 33/48
C12Q 1/00
US Classification:
134 1, 134 32, 134 42, 310311, 73 6175, 73579, 435 4, 435 71, 4352872, 436149, 436518, 436524, 436525, 422 681, 422 8201
Abstract:
The techniques described herein are directed to removing material that has attached to or preventing material from attaching to the surface of a piezoelectric cantilever. The material can be a target material, other, non-target, material that may be weakly bound or attached to the cantilever sensor, or the material may be a combination thereof. Accordingly, the cantilever sensor can be reused, in situ, without degraded detection performance of the cantilever sensor. The techniques may also be utilized to remove all material that has attached to a surface of the cantilever sensor which provides means for reusing the cantilever sensor.

Self-Exciting, Self-Sensing Piezoelectric Cantilever Sensor

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US Patent:
7942056, May 17, 2011
Filed:
Jan 23, 2007
Appl. No.:
11/625919
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
David Maraldo - Gilbertsville PA, US
Gossett Augustus Campbell - Conshohocken PA, US
Kishan Rijal - Harleysville PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
G01H 1/00
US Classification:
73579, 73 6175
Abstract:
A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the non-piezoelectric layer extends beyond the end of piezoelectric layer to provide an overhang. The overhang piezoelectric cantilever sensor enables increased sensitivity allowing application of the device in more viscous environments, such as liquid media, as well as application in liquid media at higher flow rates than conventional piezoelectric cantilevers. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form the piezoelectric cantilever sensor. In this embodiment, the sensor is robust and exhibits excellent sensing characteristics in both gaseous and liquid media, even when subjected to relatively high flow rates.

Molecular Control Of Surface Coverage

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US Patent:
8286486, Oct 16, 2012
Filed:
May 10, 2007
Appl. No.:
12/299841
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
David L. Delesdernier - Kennett Square PA, US
Kishan Rijal - Harleysville PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
G01H 13/00
US Classification:
73579
Abstract:
The concentration of a material covering a surface is controlled via an equilibrium process. Equilibrium parameters such as a concentration of the provided material, the exposure time of the material to the surface, and the surface area of an attractor applied to the surface are determined utilizing a millimeter sized piezoelectric cantilever sensor. In an example embodiment, the material is provided at a low concentration to the surface until equilibrium is attained. The amount of material accumulated on the surface is determined utilizing the cantilever sensor. The surface area of the attractor and the measured amount of material are utilized to determine the amount of the attractor surface area having the material bound thereto. Knowledge of the equilibrium parameters allows controlled surface coverage of the material on the attractor for any application. The concentration of the material adsorbed on the surface is precisely determinable and repeatable.

Detecting An Analyte Using A Piezoelectric Cantilever Sensor

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US Patent:
8474319, Jul 2, 2013
Filed:
Feb 25, 2011
Appl. No.:
13/034773
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
David Maraldo - Gilbertsville PA, US
Gossett Augustus Campbell - Conshohocken PA, US
Kishan Rijal - Harleysville PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
G01H 1/00
US Classification:
73579, 73 6175
Abstract:
A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the non-piezoelectric layer extends beyond the end of piezoelectric layer to provide an overhang. The overhang piezoelectric cantilever sensor enables increased sensitivity allowing application of the device in more viscous environments, such as liquid media, as well as application in liquid media at higher flow rates than conventional piezoelectric cantilevers. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form the piezoelectric cantilever sensor. In this embodiment, the sensor is robust and exhibits excellent sensing characteristics in both gaseous and liquid media, even when subjected to relatively high flow rates.

Self-Exciting, Self-Sensing Piezoelectric Cantilever Sensor

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US Patent:
8511163, Aug 20, 2013
Filed:
Feb 25, 2011
Appl. No.:
13/034794
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
David Maraldo - Gilbertsville PA, US
Gossett Augustus Campbell - Conshohocken PA, US
Kishan Rijal - Harleysville PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
G01H 1/00
US Classification:
73579, 31032321
Abstract:
A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the non-piezoelectric layer extends beyond the end of piezoelectric layer to provide an overhang. The overhang piezoelectric cantilever sensor enables increased sensitivity allowing application of the device in more viscous environments, such as liquid media, as well as application in liquid media at higher flow rates than conventional piezoelectric cantilevers. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form the piezoelectric cantilever sensor. In this embodiment, the sensor is robust and exhibits excellent sensing characteristics in both gaseous and liquid media, even when subjected to relatively high flow rates.

Enhanced Sensitivity Of A Cantilever Sensor Via Specific Bindings

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US Patent:
20090053709, Feb 26, 2009
Filed:
Feb 15, 2008
Appl. No.:
12/032302
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
David R. Maraldo - Gilbertsville PA, US
Kishan Rijal - Harleysville PA, US
Gossett Augustus Campbell - Gilbertsville PA, US
Paul Karl Horan - Kennett Square PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
C12Q 1/68
G01N 33/53
G01N 33/543
US Classification:
435 6, 435 71, 436518
Abstract:
Detection of miniscule amounts of an analyte is accomplished via multiple bindings of specific materials on a sensor configured to sense mass. The sensor is prepared by immobilizing an antibody to a surface of the sensor, wherein the antibody is known to bind to the analyte. The prepared sensor is exposed to the analyte. The analyte binds to the antibody. The sensor then is exposed to additional antibody, which binds to the analyte. The sensor then can be sequentially exposed to additional antibodies that are known to bind to previously bound antibodies. Each additional binding further increases the effective mass of accumulated material on the sensor. The total effective mass is greater than the mass of the accumulated analyte, thus providing means for detecting extremely minute amounts of analyte. Applications include detection of pathogens and DNA.

Detection Of Nucleic Acids Using A Cantilever Sensor

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US Patent:
20090203000, Aug 13, 2009
Filed:
Jun 18, 2008
Appl. No.:
12/141846
Inventors:
Rajakkannu Mutharasan - West Chester PA, US
Kishan Rijal - Harleysville PA, US
David R. Maraldo - Gilbertsville PA, US
Gossett Augustus Campbell - Gilbertsville PA, US
Assignee:
DREXEL UNIVERSITY - Philadelphia PA
International Classification:
C12Q 1/68
G01N 29/02
US Classification:
435 6, 73 2406
Abstract:
Detection of miniscule amounts of nucleic acid is accomplished via binding of target nucleic acid to probe material, composed of nucleic acid, which is bound to a sensor configured to sense mass. The sensor is prepared by immobilizing a probe material to a surface of the sensor, wherein the probe material is known to bind to the target nucleic acid. The prepared sensor is exposed to the target nucleic acid. The target nucleic acid binds to the probe material. The mass accumulated on the sensor reflects the amount of target nucleic acid bound to the probe material.

Detection Of Nucleic Acids Using A Cantilever Sensor

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US Patent:
20140045178, Feb 13, 2014
Filed:
Jul 31, 2013
Appl. No.:
13/955408
Inventors:
Kishan Rijal - Lansdale PA, US
David R. Maraldo - Gilbertsville PA, US
Gossett Augustus Campbell - Gilbertsville PA, US
Assignee:
Drexel University - Philadelphia PA
International Classification:
C12Q 1/68
US Classification:
435 611, 436501, 4352872, 422 69
Abstract:
Detection of miniscule amounts of nucleic acid is accomplished via binding of target nucleic acid to probe material, composed of nucleic acid, which is bound to a sensor configured to sense mass. The sensor is prepared by immobilizing a probe material to a surface of the sensor, wherein the probe material is known to bind to the target nucleic acid. The prepared sensor is exposed to the target nucleic acid. The target nucleic acid binds to the probe material. The mass accumulated on the sensor reflects the amount of target nucleic acid bound to the probe material.
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Kishan Rijal from Lansdale, PA, age ~50 Get Report