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Kenneth William Hance

from Malvern, PA
Age ~53

Kenneth Hance Phones & Addresses

  • 103 Sagewood Dr, Malvern, PA 19355 (610) 827-7428
  • Collegeville, PA
  • 95 Cherry Tree Ln, Groton, MA 01450 (978) 449-0016
  • Wilmington, NC
  • Greensboro, NC
  • Broadlands, VA
  • Burke, VA
  • Lafayette, IN

Work

Company: The wistar institute Jan 2017 to Dec 2018 Position: Visiting scientist

Education

Degree: Master of Public Health, Masters School / High School: The George Washington University 2002 to 2004 Specialities: Epidemiology

Skills

Drug Discovery • Cell Culture • Molecular Biology • Western Blotting • Vaccines • Life Sciences • In Vivo • Pharmacology • Cancer Research • Pcr • Biotechnology • Cell Biology • Flow Cytometry • Elisa • Vaccine Development • Biochemistry • Public Health • In Vivo Pharmacology • Molecular Cloning • Polymerase Chain Reaction • Lifesciences • Statistics • Fluorescence Microscopy • Confocal Microscopy • Elispot

Languages

English

Industries

Research

Resumes

Resumes

Kenneth Hance Photo 1

Senior Director And Head, Immune Biology

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Location:
290 Lapp Rd, Malvern, PA 19355
Industry:
Research
Work:
The Wistar Institute Jan 2017 - Dec 2018
Visiting Scientist

Gsk Jan 2017 - Dec 2018
Senior Director and Head, Immune Biology

Gsk Jun 2015 - Sep 2017
Director, Antibody Therapies

Emd Serono, Inc. Apr 2010 - Jun 2015
Group Leader, Immunopharmacology

National Cancer Institute (Nci) Sep 2003 - Apr 2010
Postdoctoral Research Fellow In the Laboratory of Tumor Immunology and Biology
Education:
The George Washington University 2002 - 2004
Master of Public Health, Masters, Epidemiology
Purdue University 2000 - 2002
Doctorates, Doctor of Philosophy, Biochemistry, Philosophy
Clemson University 1989 - 1993
Bachelors, Bachelor of Science
Skills:
Drug Discovery
Cell Culture
Molecular Biology
Western Blotting
Vaccines
Life Sciences
In Vivo
Pharmacology
Cancer Research
Pcr
Biotechnology
Cell Biology
Flow Cytometry
Elisa
Vaccine Development
Biochemistry
Public Health
In Vivo Pharmacology
Molecular Cloning
Polymerase Chain Reaction
Lifesciences
Statistics
Fluorescence Microscopy
Confocal Microscopy
Elispot
Languages:
English

Publications

Isbn (Books And Publications)

Principles of Speaking

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Author

Kenneth Gordon Hance

ISBN #

0534003737

Discussion in Human Affairs

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Author

Kenneth Gordon Hance

ISBN #

0837138396

Us Patents

Methods Of Diagnosing And Prognosing Colonic Polyps

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US Patent:
20120309697, Dec 6, 2012
Filed:
Oct 27, 2010
Appl. No.:
13/504154
Inventors:
Samuel Norbert Breit - Gordon, AU
David Alexander Brown - Lane Cove, AU
Kenneth W. Hance - Groton MA, US
Elaine Lanza - Clearwater FL, US
Connie J. Rogers - Olney MD, US
International Classification:
G01N 33/566
A61P 1/00
A61P 9/00
A61P 35/00
A61P 39/00
A61P 13/12
A61P 3/04
A61P 21/00
A61P 3/00
A61P 15/00
A61K 38/19
A61P 9/10
US Classification:
514 2192, 435 792, 435 71, 436501
Abstract:
Methods of diagnosing or prognosing a disease or condition associated with increased or over expression of macrophage inhibitory cytokine-1 (MIC-1) are disclosed. The methods typically involve detecting a change in the amount of MIC-1 in a test body sample from a subject taken at two or more timing points. The change in the amount of MIC-1 may be adjusted for the effect of at least the following factors as appropriate: the gender of the subject, the age of the subject, the body mass index (BMI) of the subject, the subject being a smoker, the subject being a user of NSAIDs, and the waist-to-hip ratio where the subject is female. The methods are particularly suitable for diagnosing or prognosing the presence of one or more colorectal polyp(s).

Methods Of Diagnosing And Prognosing Colonic Polyps

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US Patent:
20170205413, Jul 20, 2017
Filed:
Mar 22, 2017
Appl. No.:
15/465805
Inventors:
- New South Wales, AU
- Bethesda MD, US
Kenneth W. HANCE - Groton MA, US
Elaine LANZA - Clearwater FL, US
Connie J. ROGERS - State College PA, US
International Classification:
G01N 33/574
Abstract:
Methods of diagnosing or prognosing a disease or condition associated with increased or over expression of macrophage inhibitory cytokine-1 (MIC-1) are disclosed. The methods typically involve detecting a change in the amount of MIC-1 in a test body sample from a subject taken at two or more time points. The change in the amount of MIC-1 may be adjusted for the effect of at least the following factors as appropriate: the gender of the subject, the age of the subject, the body mass index (BMI) of the subject, the subject being a smoker, the subject being a user of NSAIDs, and the waist-to-hip ratio where the subject is female. The methods are particularly suitable for diagnosing or prognosing the presence of one or more colorectal polyp(s).

Survivin-Directed Cancer Vaccine Therapy

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US Patent:
20160279213, Sep 29, 2016
Filed:
Dec 16, 2014
Appl. No.:
15/036629
Inventors:
- Darmstadt, DE
Patrizia Boniforte - Darmstadt, DE
Joerg Plaschke - Bensheim, DE
Markus Weigandt - Mannheim, DE
Stefan Jaekel - Darmstadt, DE
Roland Kellner - Heppenheim, DE
Thomas Rysiok - Dudenhofen, DE
Dirk Mueller-Pompalla - Muehltal, DE
Kenneth Hance - Groton MA, US
International Classification:
A61K 39/00
A61K 39/39
A61K 45/06
C07K 14/47
Abstract:
The invention relates to a therapeutically effective truncated survivin and its therapeutic use as vaccine in a liposomal preparation, wherein the survivin fragment is preferably gluconoylated, and said liposomal preparation elicits in-vivo anti-tumor activity. The invention is directed, in more detail, to a cancer vaccine comprising a fragment of human survivin that is specifically effective in conjunction with an lipid adjuvant. The invention relates in more detail to a liposomal vaccine delivery system comprising an active truncated survivin molecule as tumor antigen and a chiral cationic lipid, for example R-DOTAP acting as adjuvant, which is part of the liposome preparation, wherein the liposomal drug delivery system is optimized with regard to its lipid and adjuvant components, physical or physicochemical parameters, and the final therapeutic efficacy of the released truncated survivin molecules. The invention is finally related to a method of increasing CD4/CD8 T-cell responses in-vivo, thus resulting in an increased anti-tumor activity by providing a liposome preparation comprising said truncated preferably gluconoylated survivin.

Methods Of Diagnosing And Prognosing Colonic Polyps

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US Patent:
20150198601, Jul 16, 2015
Filed:
Jan 5, 2015
Appl. No.:
14/589238
Inventors:
- Darlinghurst, AU
- Rockville MD, US
Kenneth W. HANCE - Groton MA, US
Elaine LANZA - Clearwater FL, US
Connie J. ROGERS - State College PA, US
International Classification:
G01N 33/574
G01N 27/447
G06F 19/24
Abstract:
Methods of diagnosing or prognosing a disease or condition associated with increased or over expression of macrophage inhibitory cytokine-1 (MIC-1) are disclosed. The methods typically involve detecting a change in the amount of MIC-1 in a test body sample from a subject taken at two or more time points. The change in the amount of MIC-1 may be adjusted for the effect of at least the following factors as appropriate: the gender of the subject, the age of the subject, the body mass index (BMI) of the subject, the subject being a smoker, the subject being a user of NSAIDs, and the waist-to-hip ratio where the subject is female. The methods are particularly suitable for diagnosing or prognosing the presence of one or more colorectal polyp(s).
Kenneth William Hance from Malvern, PA, age ~53 Get Report