Joseph J Talghader

6867851, Mar 15, 2005

Aug 2, 2002

10/211113

Martin Blumenfeld - Minneapolis MN, US
Joseph J. Talghader - Eden Prairie MN, US
Mark A. Sanders - Minneapolis MN, US
Scott A. Nelson - Eagan MN, US
Kraig Anderson - Woburn MA, US
Steven A. Lewis - Bloomington MN, US

Regents of the University of Minnesota - Minneapolis MN

G01N021/03

356 73

An image detection apparatus comprises a light source and a holding apparatus adapted to hold a substrate on which a biological sample may be mounted. Light from the light source impinges on the biological sample and causes light that is representative of the sample to be emitted from the sample. A light detector is positioned in the path of the emitted light and is scanned across the emitted light. The emitted light may be focused on the light detector with an optical assembly. The emitted light may be generated by chromophores on probes in the biological sample.

7145645, Dec 5, 2006

May 10, 2001

09/852375

Martin Blumenfeld - Minneapolis MN, US
Mark A. Sanders - Minneapolis MN, US
Joseph J. Talghader - Eden Prairie MN, US
Jesse R. Grenz - Minneapolis MN, US

Regents of the University of Minnesota - Minneapolis MN

G01N 21/03

356 73

A system and method using an electronic light detector array, e. g. , a CCD or a CMOS-based detector array, is used to acquire a visual image of a biological sample that includes biological material associated with a biological material holding structure (e. g. , a DNA spot array on a DNA chip, protein bands in a 2-D gel, etc. ). For example, fluorescence from a biological sample may be detected.

7800066, Sep 21, 2010

Dec 6, 2007

11/999739

Joseph J. Talghader - Edina MN, US

Regents of the University of Minnesota Office for Technology Commercialization - St. Paul MN

G01J 5/20

2503381, 25033901

The present invention provides thermal detectors having an optical cavity that is optimized to couple light into a sensor. Light that is on resonance is coupled with the sensor with as high as 100% efficiency, while light off resonance is substantially reflected away. Light that strikes the sensor from the sides (i. e. not on the optical cavity axis) only interacts minimally with sensor because of the reduced absorption characteristics of the sensor. Narrowband sensors in accordance with the present invention can gain as much as 100% of the signal from one direction and spectral band, while receiving only a fraction of the normal radiation noise, which originates from all spectral bands and directions.

7968846, Jun 28, 2011

May 22, 2007

11/805240

Joseph Talghader - Edina MN, US
Yuyan Wang - Minneapolis MN, US
Michael S. Sutton - St. Paul MN, US

Regents of the University of Minnesota - St. Paul MN

G01J 5/00
G01J 5/52

2503381

A cavity thermal detector assembly is presented that allows both tunable narrowband and broadband operation. This allows for high light efficiency, low thermal time constant, and flexibility in designing the optical path. The thermal detector/filter layers are part of the top mirror or mirrors of a Gires-Tournois-type optical cavity and provide absorption and reflection that can be adjusted to the desired width and position of the detected band. Tuning, if desired, can be achieved by applying micromechanical methods. Broadband operation may be achieved by bringing the sensor close to the bottom mirror. In this mode, the sensor or its supports may or may not touch over a small area.

8629398, Jan 14, 2014

May 29, 2009

12/996704

Joseph J. Talghader - Edina MN, US
Ryan P. Shea - St. Paul MN, US
Anand S. Gawarikar - Minneapolis MN, US

The Regents of the University of Minnesota - St. Paul MN

G01J 5/20
G01J 5/02

2503384, 250340

High sensitivity thermal detectors that perform beyond the blackbody radiation noise limit are described. Thermal detectors, as described herein, use spectrally selective materials that absorb strongly in the wavelength region of the desired signal but only weakly or not at all in the primary thermal emission band. Exemplary devices that can be made in accordance with the present invention include microbolometers containing semiconductors that absorb in the MWIR and/or THz range but not the LWIR.

20070121111, May 31, 2007

Dec 4, 2006

11/566594

Martin Blumenfeld - Minneapolis MN, US
Mark Sanders - Minneapolis MN, US
Joseph Talghader - Eden Prairie MN, US
Jesse Grenz - Minneapolis MN, US

G01J 3/30
G01N 21/25

356318000, 356417000

A system and method using an electronic light detector array, e.g., a CCD or a CMOS-based detector array, is used to acquire a visual image of a biological sample that includes biological material associated with a biological material holding structure (e.g., a DNA spot array on a DNA chip, protein bands in a 2-D gel, etc.). For example, fluorescence from a biological sample may be detected.

20100294935, Nov 25, 2010

Mar 18, 2010

12/726776

Joseph J. Talghader - Edina MN, US

G01J 5/08
G01J 5/20

2503384, 250340, 250353, 250352

The present invention provides thermal detectors having an optical cavity that is optimized to couple light into a sensor. Light that is on resonance is coupled with the sensor with as high as 100% efficiency, while light off resonance is substantially reflected away. Light that strikes the sensor from the sides (i.e. not on the optical cavity axis) only interacts minimally with sensor because of the reduced absorption characteristics of the sensor. Narrowband sensors in accordance with the present invention can gain as much as 100% of the signal from one direction and spectral band, while receiving only a fraction of the normal radiation noise, which originates from all spectral bands and directions.

6784982, Aug 31, 2004

Nov 4, 1999

09/434027

Martin Blumenfeld - Minneapolis MN
Joseph J. Talghader - Eden Prairie MN
Mark A. Sanders - Minneapolis MN

Regents of the University of Minnesota - Minneapolis MN

G06K 974

356 71

A device for detecting the pattern of polynucleic acid hybridization to a surface, the device includes (a) a positioning device for receiving a nucleic acid chip and keeping the chip in a sampling position, the nucleic acid chip being an object with a flat sample surface and an opposed surface that is joined to the sample surface by a thickness, with the sample surface having sequences of nucleic acids immobilized thereto, with each sequence being immobilized to a particular chip address. And, (b) an electronic light detector array, the detector array comprising detector pixels, the detector pixels being sensors located at particular detector pixel addresses, wherein the sampling position places the sample surface of the chip at a well-defined position relative to the electronic light detector array so that light leaving a chip address is substantially directed onto at least one detector pixel with an address that is correlated to the chip address.