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Joelle L Burgess

from Trappe, PA
Age ~55

Joelle Burgess Phones & Addresses

  • 455 Silver Leaf Cir, Collegeville, PA 19426 (610) 831-1614
  • Trappe, PA
  • Sea Isle City, NJ
  • Harleysville, PA
  • Phoenixville, PA
  • Toledo, OH
  • Chalfont, PA
  • Montgomery, PA

Publications

Us Patents

Calcilytic Compounds

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US Patent:
6395919, May 28, 2002
Filed:
Oct 5, 2000
Appl. No.:
09/647793
Inventors:
Pradip Kumar Bhatnagar - Exton PA
Joelle Lorraine Burgess - Phoenixville PA
James Francis Callahan - Philadelphia PA
Raul Rolando Calvo - Royersford PA
Eric G. Del Mar - Salt Lake City UT
Maria Amparo Lago - Audubon PA
Thomas The Nguyen - King of Prussia PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
NPS Pharmaceuticals - Salt Lake City UT
International Classification:
C07C25503
US Classification:
558414, 560 36, 562451
Abstract:
Novel calcilytic compounds, pharmaceuticals compositions cotaining said compounds and their use as calcium receptor antagonists.

Triarylimidazoles

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US Patent:
6465493, Oct 15, 2002
Filed:
Oct 9, 2001
Appl. No.:
09/958639
Inventors:
Joelle L. Burgess - Collegeville PA
James F. Callahan - Collegeville PA
Assignee:
Smithkline Beecham Corporation - Philadelphia PA
International Classification:
A61K 3144
US Classification:
514341, 514277, 514340, 514342, 514357, 5462697, 5462714, 5462727, 5462764, 5462804, 5462834, 546329, 546339
Abstract:
Compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein R , R and R are various substituent groups; and one of X and X is N or CRâ, and the other is NRâ or CHRâ wherein Râ is hydrogen, OH, C alkyl, or C cycloalkyl; or when one of X and X is N or CRâ then the other may be S or O; and their use as pharmaceuticals.

Quinoline Inhibitors Of Hyaki And Hyak3 Kinases

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US Patent:
7087758, Aug 8, 2006
Filed:
Apr 4, 2002
Appl. No.:
10/474084
Inventors:
Deborah L. Bryan - King of Prussia PA, US
Joelle L. Burgess - Collegeville PA, US
James F. Callahan - Collegeville PA, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31/47
C07D 215/38
C07D 215/12
US Classification:
546161, 546167, 546159, 514311, 514314
Abstract:
This invention relates to novel quinoline inhibitors of hYAK1 and hYAK3 kinases and pharmaceutically acceptable salts, hydrates or solvates thereof, pharmaceutical compositions thereof, and methods of treatment of diseases in which an excessive amount of either such kinase is a factor.

Calcilytic Compounds

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US Patent:
7109238, Sep 19, 2006
Filed:
Jan 21, 2004
Appl. No.:
10/761986
Inventors:
Maria Amparo Lago - Audubon PA, US
James Francis Callahan - Philadelphia PA, US
Pradip Kumar Bhatnagar - Exton PA, US
Eric G. Del Mar - Salt Lake City UT, US
William M. Bryan - Phoenixville PA, US
Joelle L. Burgess - Trappe PA, US
Assignee:
Smith Kline Beecham Corporation - Philadelphia PA
NPS Pharmaceuticals, Inc. - Salt Lake City UT
International Classification:
A61K 31/335
A61K 31/195
C07C 303/08
C07C 63/04
C07D 255/03
US Classification:
514475, 514567, 514520, 514521, 549551, 558414, 560 51, 562493
Abstract:
Novel calcilytic compounds and methods of using them are provided.

Nf-Κb Inhibitors

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US Patent:
7166639, Jan 23, 2007
Filed:
Oct 4, 2002
Appl. No.:
10/491710
Inventors:
Zehong Wan - King of Prussia PA, US
Joelle L. Burgess - Collegeville PA, US
James F. Callahan - King of Prussia PA, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31/38
C07D 333/36
US Classification:
514447, 549 68
Abstract:
The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.

Chemical Compounds

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US Patent:
7482455, Jan 27, 2009
Filed:
Oct 15, 2003
Appl. No.:
10/530986
Inventors:
Joelle L. Burgess - King of Prussia PA, US
James F. Callahan - King of Prussia PA, US
Toshihiro Hamajima - Ibaraki, JP
Satoru Ida - Keita NE, US
Ichiro Mori - Aichi, JP
Jun Tang - Ibaraki, JP
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D 215/38
US Classification:
546157, 546156, 546153
Abstract:
3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.

Quinoline Derivatives As P13 Kinase Inhibitors

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US Patent:
8404837, Mar 26, 2013
Filed:
May 16, 2008
Appl. No.:
12/600745
Inventors:
Nicholas D. Adams - Collegeville PA, US
Joelle Lorraine Burgess - Collegeville PA, US
Michael Gerard Darcy - Collegeville PA, US
Carla A. Donatelli - Collegeville PA, US
Steven David Knight - Collegeville PA, US
Kenneth Allen Newlander - Collegeville PA, US
Lance Ridgers - Collegeville PA, US
Martha A. Sarpong - Collegeville PA, US
Stanley J. Schmidt - Collegeville PA, US
Assignee:
GlaxoSmithKline LLC - Philadelph PA
International Classification:
C07D 401/14
C07D 413/14
C07D 498/04
US Classification:
544105, 544128, 546167
Abstract:
Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.

Azaindazoles

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US Patent:
8637509, Jan 28, 2014
Filed:
May 5, 2011
Appl. No.:
13/696601
Inventors:
Joelle Lorraine Burgess - Collegeville PA, US
Neil Johnson - Collegeville PA, US
Steven D. Knight - Collegeville PA, US
Louis LaFrance - Collegeville PA, US
William H. Miller - Collegeville PA, US
Kenneth Newlander - Collegeville PA, US
Stuart Romeril - Collegeville PA, US
Meagan B. Rouse - Collegeville PA, US
Xinrong Tian - Collegeville PA, US
Sharad Kumar Verma - Collegeville PA, US
Dominic Suarez - Collegeville PA, US
Assignee:
GlaxoSmithKline LLC - Philadelphia PA
International Classification:
A61K 31/444
A61P 35/00
A61K 31/506
A61K 31/5377
A61K 31/513
C07D 471/04
A61K 31/4545
US Classification:
5142342, 514303, 51425304, 514274, 514272, 544127, 544362, 544310, 544331, 546120
Abstract:
Herein are disclosed azaindazoles of formula (I).
Joelle L Burgess from Trappe, PA, age ~55 Get Report