Resumes
Resumes
Jill Haizlip Phones & Addresses
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3332 William Newlin Dr, Graham, NC 27253
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Chapel Hill, NC
Work
Position:
Professional/Technical
Education
Degree:
High school graduate or higher
Publications
Us Patents
High Throughput Method For Screening Candidate Compounds For Biological Activity
View pageUS Patent:
20080009019, Jan 10, 2008
Filed:
Jan 17, 2007
Appl. No.:
11/623983
Inventors:
Jill Haizlip - Durham NC, US
Diane Ignar - Durham NC, US
Channa Jayawickreme - Durham NC, US
Holly King - Durham NC, US
James Liacos - Durham NC, US
Kirsten Mills - Stevenage, GB
Jason Ruan - Cambridge MA, US
Howard Sauls - Durham NC, US
Joel Shaffer - Durham NC, US
Diane Ignar - Durham NC, US
Channa Jayawickreme - Durham NC, US
Holly King - Durham NC, US
James Liacos - Durham NC, US
Kirsten Mills - Stevenage, GB
Jason Ruan - Cambridge MA, US
Howard Sauls - Durham NC, US
Joel Shaffer - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
G01N 33/567
G01N 33/53
G01N 33/543
G01N 33/53
G01N 33/543
US Classification:
435007200, 435007100, 436518000
Abstract:
A method for screening candidate compounds for an ability to modulate the biological activity of a target. The method includes the steps of providing a substrate comprising a target and an indicator, the substrate adapted for receiving a plurality of candidate compounds; contacting the substrate with a plurality of candidate compound samples in a manner wherein an identity of each candidate compound can be determined and wherein the candidate compounds in the candidate compound samples interact with the target in the substrate; detecting a signal, the signal produced by the indicator upon interaction between the target and a candidate compound; and identifying a candidate compound as a modulator of the biological activity of the target based upon an amount of signal produced.
High Throughput Method For Screening Candidate Compounds For Biological Activity
View pageUS Patent:
20030219825, Nov 27, 2003
Filed:
Dec 12, 2002
Appl. No.:
10/297976
Inventors:
Jill Haizlip - Durham NC, US
Diane Ignar - Durham NC, US
Channa Jayawickreme - Durham NC, US
Holly King - Durham NC, US
James Liacos - Durham NC, US
Kirsten Mills - Research Triangle Park NC, US
Jason Ruan - Cambridge MA, US
Howard Sauls Jr - Durham NC, US
Joel Shaffer - Durham NC, US
Diane Ignar - Durham NC, US
Channa Jayawickreme - Durham NC, US
Holly King - Durham NC, US
James Liacos - Durham NC, US
Kirsten Mills - Research Triangle Park NC, US
Jason Ruan - Cambridge MA, US
Howard Sauls Jr - Durham NC, US
Joel Shaffer - Durham NC, US
International Classification:
G01N033/53
G01N033/567
G01N033/543
G01N033/567
G01N033/543
US Classification:
435/007100, 435/007200, 436/518000
Abstract:
A method for screening candidate compounds for an ability to modulate the biological activity of a target. The method includes the steps of providing a substrate comprising a target and an indicator, the substrate adapted for receiving a plurality of candidate compounds; contacting the substrate with a plurality of candidate compound samples in a manner wherein an identity of each candidate compound can be determined and wherein the candidate compounds in the candidate compound samples interact with the target in the substrate; detecting a signal, the signal produced by the indicator upon interaction between the target and a candidate compound; and identifying a candidate compound as a modulator of the biological activity of the target based upon an amount of signal produced.