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Jerome A Iacobelli

from Paramus, NJ
Deceased
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Also known as:
Jeorome Iacobelli
Phone and address:
459 Tulane Ct, Paramus, NJ 07652
(201) 967-1935
Related to:
James P Gavin, 59Aurelia M Iacobelli, 84Joseph B Messina, 60Aurelia Messina, 84
Connected to:
Bruce M Iacobelli, 74Christopher J Iacobelli, 59Claudio Iacobelli, 36Frank Iacobelli, 50James Iacobelli, 41John Iacobelli, 42Karen E Iacobellis, 67Luciano Iacobelli, 77Nancy Iacobellis, 56Salvatore Iacobello, 64

Jerome Iacobelli Phones & Addresses

  • 459 Tulane Ct, Paramus, NJ 07652 (201) 967-1935
  • Woodside, NY
  • 459 Tulane Ct, Paramus, NJ 07652 (201) 927-6552

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Publications

Us Patents

Vitamin D3 Analogs

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US Patent:
6452028, Sep 17, 2002
Filed:
Aug 25, 2000
Appl. No.:
09/648825
Inventors:
Andrew David Batcho - North Caldwell NJ
Bernard Michael Hennessy - Nutley NJ
Jerome Anthony Iacobelli - Paramus NJ
Milan Radoje Uskokovic - Upper Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07C40100
US Classification:
552653, 514167
Abstract:
A compound of the formula wherein R is hydrogen or hydroxy, each R is ethyl, propyl, butyl, isopropyl or t-butyl, X is CH , or when R is hydroxy, X is hydrogen or CH , and A is âCâCâ, or âCH âCH â. These compounds are useful for the treatment of hyperproliferative disorders, skin diseases, and sebaceous gland diseases.

Process For The Preparation Of 1.Alpha.,25-Dihydroxycholecalciferol

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US Patent:
39936759, Nov 23, 1976
Filed:
Feb 24, 1975
Appl. No.:
5/552027
Inventors:
Milan Radoje Uskokovic - Upper Montclair NJ
Thomas Albert Narwid - Pompton Plains NJ
Jerome Anthony Iacobelli - Woodside NY
Enrico Baggiolini - Nutley NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07J 500
US Classification:
2603972
Abstract:
A novel process for the preparation of 1. alpha. ,25-dihydroxycholecalciferol and intermediates thereof is disclosed.

Vitamin D.sub.3 Analogs

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US Patent:
59394080, Aug 17, 1999
Filed:
Sep 29, 1998
Appl. No.:
9/163037
Inventors:
Andrew David Batcho - North Caldwell NJ
Bernard Michael Hennessy - Nutley NJ
Jerome Anthony Iacobelli - Paramus NJ
Milan Radoje Uskokovic - Upper Montclair NJ
Assignee:
Hoffman-La Roche Inc. - Nutley NJ
International Classification:
A61K 3159
C07C40100
US Classification:
514167
Abstract:
Compounds of the formula ##STR1## wherein R is hydrogen, fluorine, or hydroxyl, each R. sub. 2 is lower alkyl or C(R. sub. 3). sub. 3 and R. sub. 3 is halogen, X is. dbd. CH. sub. 2 or when R is hydroxy, X is hydrogen or. dbd. CH. sub. 2, and A is --C. tbd. C-- ##STR2## or --CH. sub. 2 --CH. sub. 2 --, which are useful in the treatment of hyperproliferative skin disorders, neoplastic diseases, and sebaceous gland diseases.

16-Ene-26,27-Bishomo Cholecalciferols

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US Patent:
60309636, Feb 29, 2000
Filed:
Jul 31, 1998
Appl. No.:
9/127449
Inventors:
Jerome Anthony Iacobelli - Paramus NJ
Milan Radoje Uskokovic - Upper Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
A01N 4500
C07C40100
US Classification:
514167
Abstract:
The invention relates to a compound of the formula ##STR1## wherein A is ##STR2## Et is ethyl, and R is hydroxy and R. sup. 1 is hydrogen or. dbd. CH. sub. 2 or R is hydrogen or fluoro and R. sup. 1 is. dbd. CH. sub. 2. Compounds of formula I stimulate HL-60 cell differentiation. Accordingly, the compounds of formula I are useful as agents for the treatment of neoplastic diseases, such as leukemia.

22-Epimeric-1,25-Dihydroxy-16,22,23-Triene-Cholecalciferol

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US Patent:
58407189, Nov 24, 1998
Filed:
Mar 6, 1997
Appl. No.:
8/811809
Inventors:
Bernard Michael Hennessy - Nutley NJ
Jerome Anthony Iacobelli - Paramus NJ
Milan Radoje Uskokovic - Upper Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
A61K 3159
US Classification:
514167
Abstract:
The invention relates to a compound of the formula ##STR1## wherein R is hydroxy and R. sup. 1 is H. sub. 2 or. dbd. CH. sub. 2 or R is hydrogen or fluoro and R. sup. 1 is. dbd. CH. sub. 2 and (b) an inert carrier. Compounds of formula I are useful as agents for the treatment of hyperproliferative skin diseases, such as psoriasis, neoplastic diseases, such as leukemia, and sebaceous gland diseases, such as acne and sebhorreic dermatitis.

Vitamin D3 Analogs

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US Patent:
63295385, Dec 11, 2001
Filed:
Aug 25, 2000
Appl. No.:
9/648817
Inventors:
Andrew David Batcho - North Caldwell NJ
Bernard Michael Hennessy - Nutley NJ
Jerome Anthony Iacobelli - Paramus NJ
Milan Radoje Uskokovic - Upper Montclair NJ
Assignee:
Hoffmann-La Roche Inc. - Nutley NJ
International Classification:
C07C40100
A61K 3159
US Classification:
552653
Abstract:
A compound of the formula ##STR1## wherein R is hydrogen or hydroxy, each R. sup. 2 is independently H or halogen, X is. dbd. CH. sub. 2, or when R is hydroxy, X is hydrogen or. dbd. CH. sub. 2, and A is --C. ident. C--, ##STR2## or --CH. sub. 2 --CH. sub. 2 --, provided that when A is --CH. sub. 2 --CH. sub. 2 --, R. sub. 2 is H.
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Jerome A Iacobelli from Paramus, NJDeceased Get Report