Jacob J Guth

7416869, Aug 26, 2008

Aug 19, 2004

10/922790

Jacob Guth - Upper Black Eddy PA, US
Vickie Lentner - Hunterdon NJ, US

Lonza Ltd. - Basel

C12N 11/04
C12N 9/96
C12N 9/02
A61K 8/66
A61K 8/02

435188, 424 7014, 424 941, 424401, 424455, 435182, 435189, 435198, 435226

Aqueous enzyme delivery systems as well as aqueous cosmetics and personal care products were provided which comprise at least one stabile enzyme and a polyglycerol containing at least 15 carbons. In addition, stabile non-aqueous enzyme delivery systems which are dispersions of at least one enzyme in an non-aqueous viscous liquid as well as a methods for the treatment of human skin in recreational water applications by means of enzymes are provided.

8597694, Dec 3, 2013

Apr 10, 2009

12/935888

Jacob Guth - Upper Black Eddy PA, US
Joseph Boothe - Calgary, CA
Mitch Beazer - Calgary, CA
Kent Shafer - Calgary, CA

Sembiosys Genetics, Inc. - Alberta

A01N 65/00

424725

The physical stability of oleosomes is preserved in a composition by introducing a multihydric alcohol and an acid that can reduce the pH of the composition of less than 6. The resultant composition can be useful in the manufacture of cosmetic, food, and pharmaceutical products, among others.

20050100519, May 12, 2005

Mar 29, 2004

10/812746

Jacob Guth - Upper Black Eddy PA, US
Michael Czuczak - Dayton NJ, US
Vickie Lentner - Hunterdon NJ, US

Lonza Inc. - Fair Lawn NJ

A61K007/135
A61K038/46
A61K031/225
A61K031/19

424062000, 424094650, 514547000, 514557000, 514565000

The present invention is a topical composition comprising (a) L-carnitine, an acyl L-carnitine, a salt thereof, or a mixture thereof and (b) one or more hydroxy acids, proteolytic enzymes, skin lightening agents, or a mixture thereof, in a pharmacologically acceptable vehicle for topical application. The topical composition may be administered to improve or prevent deleterious skin conditions (e.g., epidermal exfoliation and loss of skin elasticity), exfoliate skin, accelerate skin turnover, and/or lighten skin. For example, it can be administered to minimize scar formation due to varicella infection, drying and peeling due to sunburn, and to improve skin elasticity. The topical composition preferably has a pH ranging from about 3.5 to about 8. According to one embodiment, the pH of the topical composition ranges from about 3.5 to about 6.5 or 7. According to another embodiment, the pH of the topical composition ranges from about 6 to about 8 and preferably from about 6.5 to 7.5. According to one preferred embodiment, the topical composition is preferably substantially free of D-carnitine, acyl D-carnitine, and salts thereof and, more preferably, is further substantially free of LD-carnitine, acyl LD-carnitine, and salts thereof.

20060093634, May 4, 2006

Apr 22, 2005

11/112479

Patrick Lutz - Nazareth PA, US
Kristy Winters - Middlesex NJ, US
Kelly Dunn - High Bridge NJ, US
Jacob Guth - Upper Black Eddy PA, US

Lonza Inc. - Fair Lawn NJ

A61K 8/37
A61K 8/49

424401000

The present invention relates to color stable personal care compositions that provide anti-oxidiation, moisturization, and/or prevent biodegradation in personal care formulations. These compositions contain erythorbic acid or a salt thereof, caffeic acid or a salt thereof, δ-gluconolactone, or a mixture thereof. The present invention further relates to methods of moisturizing skin with erythorbic acid or a salt thereof, or δ-gluconolactone. The present invention also relates to concentrates of active ingredients preloaded with a sufficient amount of an anti-oxidation, moisturizing and/or biodegradation prevention agent so that when it is diluted for use, the final formulation includes an anti-oxidation, moisturizing and/or biodegradation prevention effective amount of the anti-oxidation, moisturizing, and/or biodegradation prevention agent.

20070148119, Jun 28, 2007

Mar 9, 2007

11/684144

Jacob Guth - Upper Black Eddy PA, US
Vickie Lentner - Washington NJ, US

LONZA LTD. - Basel

A61K 8/64
C12N 9/02
C12N 11/04
C12N 9/16
C12N 9/64

424070140, 435189000, 435196000, 435182000, 435226000

Aqueous enzyme delivery systems as well as aqueous cosmetics and personal care products were provided which comprise at least one stabile enzyme and a polyglycerol containing at least 15 carbons. In addition, stabile non-aqueous enzyme delivery systems which are dispersions of at least one enzyme in an non-aqueous viscous liquid as well as a methods for the treatment of human skin in recreational water applications by means of enzymes are provided.

20080241082, Oct 2, 2008

Apr 4, 2005

10/596116

Jacob Guth - Upper Black Eddy PA, US
Vickie Lentner - Hunterdon NJ, US

Lonza Inc. - Allendale NJ

A61K 8/06
A61K 8/97
A61Q 1/10
A61Q 17/04

424 59, 424 63

A novel method is disclosed for the preparation of oil-in-water emulsions suitable for cosmetic or topical dermatological products. The method comprises the step of mixing at least one cosmetically active ingredient with an aqueous emulsion of washed vegetable oil bodies (oleosomes) and the temperature of the products does never exceed about 40 C. during the steps of the method.

20110081386, Apr 7, 2011

Apr 10, 2009

12/935069

Jacob Guth - Upper Black Eddy PA, US
John Ferguson - Lawrenceville PA, US

A61K 8/11
A61K 9/00
A61Q 19/00
A61P 17/00
A23D 9/04
A23P 1/04

424400, 426 98, 426302

The release rate of an active agent from oleosomes can be modulated by formulation of the oleosomes with a release control agent, such as a multihydric alcohol. In this context, oleosomes containing an active agent may be used in the preparation of a variety of formulations, including formulations for topical use.

63037947, Oct 16, 2001

Dec 22, 1998

9/218846

Jacob J. Guth - Upper Black Eddy PA
Samual A. Vona - Bound Brook NJ
John S. Thomaides - Berkeley Heights NJ
Doreen Howard - Plainsboro NJ
Paul M. Petersen - Princeton NJ
Carmine Iovine - Bridgewater NJ

National Starch & Chemical Investment Holding Corp. - Wilmington DE

A61K 711
A61K 3174
C07D20740

548547

This invention relates to water-soluble/dispersible reactive functionalized imido and polyimido compounds, wherein the polyimido compounds may be selected from the group consisting of polysuccinimide compounds, polyglutimide compounds, and copolymers of thereof. The polyimido compound comprises a functionalizing moiety F that provides functionality to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates; and a water-solubilizing/dispersing moiety that provides water-solubility and/or water-dispersibility to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates. The invention also pertains to a proteinaceous substrate to which the imido or polyimido compound has been covalently bonded and to a method for treating a proteinaceous substrate with the imido or polyimido compound.