Hsiaoho Edward Tung

7438852, Oct 21, 2008

Nov 15, 2004

10/989935

Hsiaoho Edward Tung - San Diego CA, US
Yuchang Wu - Hangzhou, CN
Jeling Dai - Hanzhou, CN
Ying Yang - Hanzhou, CN

Inverness Medical Switzerland GmbH - Zug

G01N 33/00

422 61, 422 55, 422 56, 422 58, 422100, 422102

The present invention is directed to devices and methods for collecting liquid samples and of testing the sample for the presence of an analyte of interest and/or a physical property. In one embodiment the device is a urine cup having an interior for containing a liquid sample, a lid, and a chamber for holding liquid. The device contains a test component for determining the presence of an analyte in the liquid sample and/or a physical property. A tube is immersed in liquid sample when the device is filled with liquid sample to be tested. When the lid is applied to the device (e. g. , by screwing or snapping on), liquid sample is forced through the tube and into the chamber holding the test component.

7517495, Apr 14, 2009

Jan 27, 2004

10/766204

Yuzhang Wu - Zhejiang, CN
Ying Yang - Zhejiang, CN
Jieling Dai - Zhejiang, CN
Hsiaoho Edward Tung - San Diego CA, US

Inverness Medical Switzerland GmbH

G01N 33/00

422 61, 422 681, 422 99, 422102, 422104

Disclosed is a device for collecting a fluid specimen. The device comprises a container that can receive a fluid specimen; a plunger movably positioned within the container, wherein the plunger can move from an initial position at an upper region of the container to a secondary position below the first position; a fluid segregation chamber that can receive a portion of the fluid specimen from the container, wherein any fluid in the segregation chamber is segregated from the fluid specimen in the container; a fluid flow lumen that provides a passageway for at least a portion of the fluid specimen to flow into the fluid segregation chamber, wherein a first end of the passageway has a first opening that opens into the fluid segregation chamber and a second end of the passageway has a second opening that can receive at least a portion of the fluid specimen; and a seal member that covers the first opening or the second opening to prevent fluid from flowing therethrough. A test element can be used to push the plunger from the initial position toward the secondary position to break the seal member and cause at least a portion of the fluid specimen to flow through the second opening into the fluid flow lumen and into the fluid segregation chamber through the first opening.

7544324, Jun 9, 2009

Nov 15, 2004

10/990324

Hsiaoho Edward Tung - San Diego CA, US
Yuzhang Wu - Hangzhou, CN
Jielin Dai - Hangzhou, CN
Ying Yang - Hangzhou, CN

Oakville Hong Kong Company Limited - Central

G01N 21/00
G01N 9/30
G01N 31/22
G01N 33/48

422 56, 422 64, 422 72, 422102, 436165

The present invention provides test devices for detecting an analyte suspected of being present in a liquid sample. The devices contain a reservoir compartment, a test compartment, and a port for a sample collection well. The devices also have a rotatable sample collection well located in the port. The device has an upper chamber for insertion of a sample applicator, an expression plate for wringing out the sample applicator and applying sample to the device, a lower chamber, and an aliquot outlet and a reservoir outlet for the movement of sample through the device. The device also contains test elements for detecting the analyte of interest. By rotating the sample collection well, the operator is able to direct distribution of collected sample in the device. Methods of using the devices and kits containing the devices are also provided.

7550112, Jun 23, 2009

Nov 15, 2004

10/990297

Lijian Gou - Hangzhou, CN
Yuzhang Wu - Hangzhou, CN
Jielin Dai - Hangzhou, CN
Hsiaoho Edward Tung - San Diego CA, US

Oakville Hong Kong Company Limited - Central, Hong Kong

G01N 21/00
B01L 3/00
G01N 21/77
G01N 21/03

422 58, 422 61, 422102, 436169, 436165

Medical and environmental diagnostic devices are described and claimed. Preferred embodiments feature cup within cup configurations wherein one cup is dedicated, for the most part, to sample collection and another cup is dedicated, for the most part, to assay performance. Communication between the cups is afforded by what is believed to be a unique valve assembly and lid tandem.

7837939, Nov 23, 2010

Aug 20, 2007

11/894108

Hsiaoho E. Tung - San Diego CA, US
Yuzhang Wu - Hangzhou, CN
Jeilin Dai - Hangzhou, CN
Ying Yang - Hangzhou, CN

Alere Switzerland GmbH - Zug

G01N 21/00
G01N 31/22

422 58, 422 50, 422 55, 422 61, 422 681, 436518, 436164, 436165, 4352831, 4352871, 4352887

The present invention is directed to devices and methods for determining the presence of analyte in a fluid sample. The devices utilize a sample collection well, an expression plate for expressing sample into the sample collection well, a plunger that drives a lance, and a test compartment containing test elements. The devices also preserve an aliquot of fluid sample in a reservoir for later confirmation testing. When the plunger is lowered into the sample collection well, a lance on the device punctures a frangible material that covers a sample outlet. When the sample outlet is thus opened, fluid sample flows from the sample collection cup to the test compartment. In one embodiment the plunger is lowered as a cap is applied to the device. The devices are useful for detecting the presence of analyte in a wide variety of fluid samples, such as saliva, oral fluids, and more. The invention also provides methods of using the devices, and kits containing the devices.

8486353, Jul 16, 2013

Aug 27, 2007

11/845346

Yuzhang Wu - Hangzhou, CN
Lijiang Guo - Hangzhou, CN
Jeilin Dai - Hangzhou, CN
Hsiaoho Tung - San Diego CA, US

Alere Switzerland GmbH - Zug

B01L 3/00

422557

Medical and environmental diagnostic devices are described and claimed. Preferred embodiments feature cup () within cup configurations wherein one cup is dedicated, for the most part, to sample collection and another cup () is dedicated, for the most part, to assay performance. Communication between the cups is afforded by what is believed to be a unique valve assembly () and lid () tandem.

20020058031, May 16, 2002

Sep 17, 2001

09/957145

Hsiaoho Tung - San Diego CA, US
Robert Hudak - Carlsbad CA, US

A61K039/395
C12P021/04
G01N033/53
G01N033/542

424/140100, 435/070210, 435/007900, 530/388100, 435/326000

The present invention utilizes human antibodies to identify and produce antigen preparations that are particularly useful for the detection, diagnosis, prognosis or prevention of human etiological agents or human disease states or conditions. The present invention provides a variety of aspects, including antigenic preparations, antibody preparations, methods of making such preparations and methods of using such preparations. The present invention is: a method for preparing a composition relating to a human etiological agent and/or a human diseased state or condition. a method for detecting an antibody and/or an antigen that binds with an antigenic preparation relating to a human etiological agent and/or to a human diseased state or condition. a composition a method for antibody preparation; an antibody, an antibody preparation, a hybridoma or a cell. a diagnostic tool, a test a region or a zone.

20040237674, Dec 2, 2004

May 27, 2004

10/855155

Yuchang Wu - Hangzhou, CN
Hsiaoho Tung - San Diego CA, US
Huiyan Guo - San Diego CA, US
Fei Gao - Hangzhou, CN
Jielin Dai - Hangzhou, CN
Haipeng Hu - Hangzhou, CN

G01N001/00

073/864000

The present invention is a device for conveniently collecting and storing liquid samples, as well as applying an aliquot of the sample to a test device, such as a lateral flow immunoassay. The present invention comprises an absorbent swab and a dropper container containing an expression means for expressing the collected sample from the swab. After the collected sample has been expressed into the reservoir of the device, the device is capped. The device can be inverted over a test device, the sides of the reservoir squeezed and an aliquot of the sample applied, in a drop-wise manner, to the sample application well of the test device. The present invention is particularly useful for collecting viscous samples, such as saliva or oral fluid, in a drug of abuse testing setting.