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Horst Malke Phones & Addresses

  • Edmond, OK
  • Oklahoma City, OK

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Us Patents

Streptokinase-Coding Recombinant Vectors

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US Patent:
50665898, Nov 19, 1991
Filed:
Jun 27, 1988
Appl. No.:
7/212254
Inventors:
Joseph J. Ferretti - Oklahoma City OK
Horst Malke - Oklahoma City OK
Assignee:
Board of Regents of the University of Okla. - Norman OK
International Classification:
C12N 1500
C12N 970
C12N 120
C07H 1512
US Classification:
4351723
Abstract:
A recombinant vector adapted for transformation of a suitable microorganism host to produce and secrete streptokinase. The recombinant vector comprises a plasmid into which a polydeoxyribonucleotide fragment from Streptococcus equisimilis H46A which codes for streptokinase synthesis and secretion has been inserted. The transformant microorganism including this recombinant plasmid vector produces streptokinase suitable for clinical fibrinolytic usage after purification.

Streptokinase-Coding Recombinant Vectors

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US Patent:
47644699, Aug 16, 1988
Filed:
Mar 2, 1984
Appl. No.:
6/585417
Inventors:
Joseph J. Ferretti - Oklahoma City OK
Horst Malke - Oklahoma City OK
Assignee:
Board of Regents for the University of Oklahoma - Norman OK
International Classification:
C12N 120
C12N 700
C12N 970
C12N 1500
C07H 1512
C12P 2100
C12P 2102
US Classification:
435216
Abstract:
A recombinant vector adapted for transformation of a suitable bacterial microorganism host to produce and secrete streptokinase. The recombinant vector comprises a plasmid into which a polydeoxyribonucleotide fragment from Streptococcus equisimilis H46A which codes for streptokinase synthesis and secretion has been inserted. The transformant bacterial microorganism including this recombinant plasmid vector produces streptokinase suitable for clinical fibrinolytic usage after purification.
Horst Malke from Edmond, OK Get Report