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Guriqbal S Basi

from Palo Alto, CA
Age ~66

Guriqbal Basi Phones & Addresses

  • 514 Rhodes Dr, Palo Alto, CA 94303 (650) 473-0984
  • Cambridge, MA
  • 514 Rhodes Dr, Palo Alto, CA 94303 (415) 424-9782

Business Records

Name / Title
Company / Classification
Phones & Addresses
Guriqbal S. Basi
Gsbio, LLC
514 Rhodes Dr, Palo Alto, CA 94303

Publications

Us Patents

-Secretase Enzyme Compositions And Methods

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US Patent:
6627739, Sep 30, 2003
Filed:
Nov 28, 2000
Appl. No.:
09/724566
Inventors:
John P. Anderson - San Francisco CA
Guriqbal Basi - Palo Alto CA
Minh Tam Doan - Hayward CA
Normand Frigon - Milbrae CA
Varghese John - San Francisco CA
Michael Power - Fremont CA
Sukanto Sinha - San Francisco CA
Gwen Tatsuno - Oakland CA
Jay Tung - Belmont CA
Shuwen Wang - Hersey PA
Lisa McConlogue - Burlingame CA
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C07K 1640
US Classification:
5303879, 5303881, 53038826, 5303891, 5303892
Abstract:
Disclosed are various forms of an active, isolated -secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimers disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (-APPwt and -APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate -secretase. Inhibitors of -secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimers disease.

Β-Secretase Enzyme Compositions And Methods

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US Patent:
7067271, Jun 27, 2006
Filed:
Nov 28, 2000
Appl. No.:
09/724571
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Milbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hersey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - So. San Francisco CA
International Classification:
C12Q 1/37
C12N 9/50
C12N 9/64
C12N 15/63
US Classification:
435 23, 435219, 435226, 435455
Abstract:
Disclosed are various forms of an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (β-APPwt and β-APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.

Β-Secretase Enzyme Compositions And Methods

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US Patent:
7109017, Sep 19, 2006
Filed:
Nov 28, 2000
Appl. No.:
09/724569
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Milbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hersey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C12N 9/82
C12N 5/06
C07H 21/04
A23J 1/00
C12P 21/06
US Classification:
435226, 536 232, 536 234, 435 691, 4353201, 43525233, 435348, 4352542, 435325, 4352523, 530350, 530412, 5303873
Abstract:
Disclosed are various forms of an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (β-APPwt and β-APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.

Β-Secretase Enzyme Compositions And Methods

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US Patent:
7115410, Oct 3, 2006
Filed:
Nov 28, 2000
Appl. No.:
09/723722
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Milbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hersey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C12N 9/64
C12N 15/00
C12N 5/00
C08G 33/66
C07H 21/04
US Classification:
435226, 530300, 4353201, 435325, 536 232
Abstract:
Disclosed are various forms of an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (β-APPwt and β-APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.

Β-Secretase Enzyme Compositions And Methods

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US Patent:
7252963, Aug 7, 2007
Filed:
Mar 25, 2005
Appl. No.:
11/090866
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Milbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hershey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C12N 9/64
C12N 9/50
C12Q 1/37
C07K 1/00
US Classification:
435 23, 435226, 435219, 530350
Abstract:
Disclosed are various forms of an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (β-APPwt and β-APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.

Beta-Secretase Enzyme Compositions And Methods

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US Patent:
7276349, Oct 2, 2007
Filed:
Mar 25, 2005
Appl. No.:
11/090872
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Milbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hershey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C12Q 1/37
C12N 9/64
C07K 1/00
US Classification:
435 23, 435226, 530350
Abstract:
Disclosed are various forms of an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (β-APPwt and β-APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.

Beta-Secretase Enzyme Compositions And Methods

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US Patent:
7427478, Sep 23, 2008
Filed:
Feb 28, 2005
Appl. No.:
11/069377
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Milbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hershey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C12Q 1/37
C12N 5/00
C12N 9/64
A64K 38/00
C07K 1/00
US Classification:
435 6, 435325, 435 721, 435226, 435 23, 530300, 530350, 536 232
Abstract:
Disclosed are various forms of an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (β-APPwt and β-APPsw) are also disclosed, as are antibodies directed to such proteins. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.

Β-Secretase Enzyme Compositions And Methods

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US Patent:
7456007, Nov 25, 2008
Filed:
Dec 24, 1999
Appl. No.:
09/471669
Inventors:
John P. Anderson - San Francisco CA, US
Guriqbal Basi - Palo Alto CA, US
Minh Tam Doan - Hayward CA, US
Normand Frigon - Millbrae CA, US
Varghese John - San Francisco CA, US
Michael Power - Fremont CA, US
Sukanto Sinha - San Francisco CA, US
Gwen Tatsuno - Oakland CA, US
Jay Tung - Belmont CA, US
Shuwen Wang - Hershey PA, US
Lisa McConlogue - Burlingame CA, US
Assignee:
Elan Pharmaceuticals, Inc. - South San Francisco CA
International Classification:
C12N 9/64
C12N 15/00
C12N 5/00
C12P 21/06
C12Q 1/68
US Classification:
435226, 4353201, 435325, 435 691, 435 6, 435 23, 4352523, 4352524, 435348, 536 232, 536412
Abstract:
Disclosed is an active, isolated β-secretase enzyme in purified and recombinant form. This enzyme is implicated in the production of amyloid plaque components which accumulate in the brains of individuals afflicted with Alzheimer's disease. Recombinant cells that produce this enzyme either alone or in combination with some of its natural substrates (APP and APPsw) are also disclosed. These compositions are useful for use in methods of selecting compounds that modulate β-secretase. Inhibitors of β-secretase are implicated as therapeutics in the treatment of neurodegenerative diseases, such as Alzheimer's disease.
Guriqbal S Basi from Palo Alto, CA, age ~66 Get Report