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Glenn Y Deng

from Sunnyvale, CA
Age ~62

Glenn Deng Phones & Addresses

  • Sunnyvale, CA
  • 1112 Arlington Ln, San Jose, CA 95129 (408) 858-7388
  • Gainesville, FL
  • Cupertino, CA
  • Santa Clara, CA
  • Monterey, CA
  • Pacific Grove, CA

Work

Company: Wuhan donghu university Aug 2013 Position: Professor and dean of college of life science and chemistry, vice president

Education

School / High School: Stanford University 1997 to 1998 Specialities: Molecular Biology

Skills

Biotechnology • Molecular Biology • Drug Discovery • Genomics • Lifesciences • Biochemistry • Technology Transfer • Cell Biology • Pharmaceutical Industry • Oncology • Clinical Development • Cell Culture • Immunology • Fda • R&D • Commercialization • Drug Development • Infectious Diseases • Cancer • Microscopy • Pcr • Assay Development

Languages

Japanese • English

Interests

Exercise • Home Improvement • Reading • Gourmet Cooking • Sports • Home Decoration • Cooking • Electronics • Outdoors • Crafts • Music • Movies • Collecting • Travel • Investing • Traveling • International Traavel • Tennis • Sports Memorabilia Collecting

Industries

Biotechnology

Resumes

Resumes

Glenn Deng Photo 1

Professor And Dean Of College Of Life Science And Chemistry, Vice President

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Location:
3380 Central Expy, Santa Clara, CA 95051
Industry:
Biotechnology
Work:
Wuhan Donghu University
Professor and Dean of College of Life Science and Chemistry, Vice President

Genetix Sep 2006 - Oct 2009
Senior Scientist
Education:
Stanford University 1997 - 1998
University of Florida 1993 - 1996
Tokyo University of Marine Science and Technology 1988 - 1992
Doctorates, Doctor of Philosophy, Biotechnology
Mie University 1986 - 1988
Master of Science, Masters, Biology
Skills:
Biotechnology
Molecular Biology
Drug Discovery
Genomics
Lifesciences
Biochemistry
Technology Transfer
Cell Biology
Pharmaceutical Industry
Oncology
Clinical Development
Cell Culture
Immunology
Fda
R&D
Commercialization
Drug Development
Infectious Diseases
Cancer
Microscopy
Pcr
Assay Development
Interests:
Exercise
Home Improvement
Reading
Gourmet Cooking
Sports
Home Decoration
Cooking
Electronics
Outdoors
Crafts
Music
Movies
Collecting
Travel
Investing
Traveling
International Traavel
Tennis
Sports Memorabilia Collecting
Languages:
Japanese
English

Publications

Us Patents

Method And Apparatus For Single Cell Isolation And Analysis

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US Patent:
20120315639, Dec 13, 2012
Filed:
May 30, 2012
Appl. No.:
13/483422
Inventors:
GLENN YAGUANG DENG - San Jose CA, US
Jie Zhang - San Jose CA, US
Fang Tian - Palo Alto CA, US
International Classification:
G01N 33/574
C12Q 1/68
C12M 1/42
G01N 33/566
US Classification:
435 612, 435 723, 435 721, 435 61, 4353091, 4352872
Abstract:
A method and apparatus are disclosed here for rare target cell enrichment and isolation, where the captured target cells can be individually picked up and used for downstream analysis. This method and apparatus utilize antibodies conjugated microbeads to isolate target cells, use ON/OFF controls for the target cell capturing magnet and the release magnet, such that there is no need to change the cap of the capturing magnet and thus enabling automatic multiple rounds of capturing, washing and releasing cycles to increase the target cell detection sensitivity and reproducibility. A special filter is utilized to effectively remove more than 95% of free unbound microbeads, thus significantly improving the purity of the collected target cells and increasing the data quality of downstream analysis of the single target cells. Lastly, RNA expression patterns are proposed for identifying of certain target cells (e.g. circulating tumor cells and white blood cells).

Floating Magnet Probe For Cell Isolation

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US Patent:
20120252088, Oct 4, 2012
Filed:
Nov 15, 2011
Appl. No.:
13/296817
Inventors:
Jie Zhang - San Jose CA, US
Glenn Y. Deng - San Jose CA, US
Fang Tien - Palo Alto CA, US
International Classification:
C12M 1/42
C12N 13/00
US Classification:
4351739, 4352831
Abstract:
A cell isolation device with an inner freely floating magnetic probe to capture and collect biological cells, such as circulating tumor cells (CTCs), during immunomagnetic incubation provides a highly efficient, low cost method to collect target cells at a single cell level. A special membrane filter may be placed above a wash well to enable separation of collected cells from free magnetic beads to yield high purity cells enabling accurate cell count. The novel approach provides a faster turn-around to separate target cells from blood, marrow or other samples with efficient removal of free magnetic beads. Cancel cell spiking experiments show a recovery rate of greater than 85%.

Apparatus And Methods To Enhance Field Gradient For Magnetic Rare Cell Separation

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US Patent:
20140248679, Sep 4, 2014
Filed:
Feb 28, 2014
Appl. No.:
14/192875
Inventors:
Jing Zhang - Los Altos CA, US
Glenn Yaguang Deng - San Jose CA, US
International Classification:
C12N 13/00
US Classification:
4351739, 4352831
Abstract:
The present invention discloses apparatus and methods to enhance magnetic field gradient for magnetic cell separation. One preferred embodiment in accordance with the invention comprises an electromagnet with an open gap formed between two pole tips and two driving coils with independently controlled electrical current magnitude and direction. In the specific case when two magnetic pole tips emanate magnetic fields with different magnitude and in opposite direction, the field gradient, and therefore the magnetic force exerted on MNPs, is advantageously enhanced. Spatial uniformity of the magnetic field gradient is also enhanced. Preferred embodiments are capable of magnetic cell separation for both positive and negative cell selection, as well as in-vitro capture and separation in miniaturized form of embodiments.

Methods And Apparatus For Target Cell Magnetic Enrichment, Isolation And Biological Analysis

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US Patent:
20140242603, Aug 28, 2014
Filed:
Feb 15, 2014
Appl. No.:
14/181671
Inventors:
Glenn Yaguang Deng - San Jose CA, US
Jing Zhang - Los Altos CA, US
Brian Deng - San Jose CA, US
International Classification:
G01N 1/40
C12Q 1/24
US Classification:
435 71, 435 30, 435 405
Abstract:
Disclosed here are methods and apparatus for target cell magnetic enrichment, isolation, and biological analysis. The target cells are labeled with magnetic nano-particles in a separate tube, container or in a device with soft magnetic collectors but not activated during the labeling period. Labeled biological samples will be used for targets enrichment and isolation using a magnetic device (permanent magnet or electromagnet). The labeled sample passes through a tube/channel within a magnetic field so the magnetic nano-particle labeled targets can be captured. Once the magnetic field is turned off, the captured targets can be released in a container. The labeling of the targets also can be performed in a device with soft magnetic collectors inside. Without magnetic activation, the device is just like a regular biological sample incubator. Thus the targets are labeled during the mixing and incubation. Once the device is placed in the magnetic field, the soft magnetic collectors are activated and the labeled target cells are isolated. After the washing process, the pure targets are released into the target collector by turning off the magnetic field with or without centrifugation. The magnet can be a permanent magnet or an electromagnet producing the magnetic field for targets to bind to the soft magnetic collectors in the device. The soft magnetic collectors can function as a magnet for capturing and releasing targets without the need of separation covers between magnet and target biological structures. The methods and apparatus improve the targets capturing sensitivity which improves the operation of the device. The methods and apparatus can be used for enrichment, isolation and material transferring.
Glenn Y Deng from Sunnyvale, CA, age ~62 Get Report