Search

Glen S Cho

from Newton, MA
Age ~51
Get Report
Related to:
John L Peacock, 49Bradley W Peacock, 22John M Pocock, 49
Connected to:
Adriana Cho, 50Angel Cho, 86Archie S Cho, 94Ariel S Cho, 33Bart Cho, 66Brian B Cho, 50Byron Y Cho, 64Candice M Cho, 60Charles H Cho, 91Choon Cho

Glen Cho Phones & Addresses

  • 74 Meadowbrook Rd, Newton Center, MA 02459
  • Newton, MA
  • Brookline, MA
  • Cambridge, MA
  • La Jolla, CA
  • San Diego, CA
  • Napa, CA

Work

Company: Harvard university Position: Research team leader ii

Skills

Product Management • Marketing • Export • Credit

Industries

Higher Education

Resumes

Resumes

Glen Cho Photo 1

Research Team Leader Ii

View page
Location:
Newton, MA
Industry:
Higher Education
Work:
Harvard University
Research Team Leader Ii
Skills:
Product Management
Marketing
Export
Credit

Publications

Us Patents

Methods, Compositions, And Kits For The Selective Activation Of Protoxins Through Combinatoral Targeting

View page
US Patent:
20100055761, Mar 4, 2010
Filed:
Jul 20, 2007
Appl. No.:
12/374616
Inventors:
Brian Seed - Boston MA, US
Jia Liu Wolfe - Winchester MA, US
Glen S. Cho - Brookline MA, US
Chia-lun Tsai - Winchester MA, US
Assignee:
THE GENERAL HOSPITAL CORPORATION - Boston MA
International Classification:
C12N 9/96
US Classification:
435188
Abstract:
The present invention provides methods and compositions for treating various diseases through selective killipg of targeted cells using a combinatorial targeting approach. The invention features protoxin fusion proteins containing a cell targeting moiety and, a modifiable activation moiety which is activated by an activation moiety not naturally operably found in, on, or in the vicinity of a target cell. These methods also include the combinatorial use of two or more therapeutic agents, at minimum comprising a protoxin and a protoxin activator, to target and destroy a specific cell population.

Engineered Thioredoxin-Like Fold Proteins

View page
US Patent:
20140113832, Apr 24, 2014
Filed:
Mar 29, 2012
Appl. No.:
14/006237
Inventors:
Jia Liu Wolfe - Winchester MA, US
Glen S. Cho - Newton MA, US
Brian Seed - Boston MA, US
Assignee:
THE GENERAL HOSPITAL CORPORATION - Boston MA
International Classification:
C07K 14/00
G01N 33/68
US Classification:
506 9, 530350, 506 18, 435 691
Abstract:
The invention features compositions based on thioredoxin-like fold protein domains described as engineered thioredoxin-like fold proteins (ETRXs). These proteins include one or more artificially diversified thioredoxin-like fold protein domains; each domain may be originated from the same or different thioredoxin-like fold protein domains. Features of the invention also include methods for identifying and preparing an enriched composition of target binding, loop-diversified ETRXs with additional sequence variations to improve affinity, stability, selectivity, or solubility. The invention also features compositions of ETRXs substituted with prosthetic groups, polymers, proteins, nucleic acids, carbohydrates, metals, natural or synthetic small molecules and toxins.
Control profile
Glen S Cho from Newton, MA, age ~51 Get Report