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Gil Benedek Phones & Addresses

  • Portland, OR

Work

Company: Ohsu May 2010 Position: Post doc

Education

Degree: PhD School / High School: The Hebrew University 2000 to 2010 Specialities: Immunology

Languages

Hebrew

Industries

Research

Resumes

Resumes

Gil Benedek Photo 1

Postdoc At Ohsu, Grantee Of The National Ms Society Postdoc Fellowship

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Position:
POST DOC at OHSU
Location:
Portland, Oregon Area
Industry:
Research
Work:
OHSU since May 2010
POST DOC
Education:
The Hebrew University 2000 - 2010
PhD, Immunology
Languages:
Hebrew

Publications

Us Patents

Recombinant Polypeptides Comprising Mhc Class Ii A1 Domains

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US Patent:
20150098956, Apr 9, 2015
Filed:
Oct 3, 2014
Appl. No.:
14/506502
Inventors:
- Portland OR, US
- Washington DC, US
Gil Benedek - Portland OR, US
Gregory G. Burrows - Portland OR, US
International Classification:
C07K 14/705
C07K 14/74
US Classification:
4241851, 530350, 514 179, 4353201, 43525233, 43525231, 43525423, 435361, 435365, 435367, 435348, 43525421, 435326
Abstract:
Recombinant polypeptides comprising a DRα1 domain, an antigenic peptide, and a linker sequence are disclosed. The linker sequence comprises a first glycine-serine spacer, a thrombin cleavage site and a second glycine-serine spacer. Further disclosed are pharmaceutical compositions comprising the recombinant polypeptides, methods of treating inflammatory disease using said pharmaceutical compositions, and expression constructs comprising nucleic acids that encode the recombinant polypeptides.

Partial Mhc Constructs And Methods Of Use

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US Patent:
20150044245, Feb 12, 2015
Filed:
Jan 4, 2013
Appl. No.:
14/370454
Inventors:
- Portland OR, US
- Washington DC, US
Roberto Meza-Romero - Hillsboro OR, US
Gil Benedek - Portland OR, US
Shayne Andrew - Beaverton OR, US
Jeffery Mooney - Portland OR, US
International Classification:
C07K 14/705
C12Q 1/68
G01N 33/569
US Classification:
4241851, 530350, 536 235, 4353201, 435 724, 435375, 435 612
Abstract:
Disclosed herein are isolated major histocompatibility complex (MHC) class II α1 domain polypeptides and methods of use. In some embodiments, the isolated polypeptide comprises or consists of an MHC class II α1 domain polypeptide (or portion thereof) and does not include an MHC class II α2, β1, or β2 domain. The disclosed MHC class II α1 domain polypeptides are of use in treating or inhibiting disorders in a subject, such as inflammatory and/or autoimmune disorders. Also disclosed are methods of evaluating efficacy of treatment or optimizing treatment of a subject with a polypeptide including an MHC class II α1 domain polypeptide (or portion thereof) or a polypeptide including an MHC class II α1 domain and β1 domain (such as a β1α1 RTL).
Gil Benedek from Portland, OR, age ~48 Get Report