Inventors:
Xuemei Cao - East Lyme CT, US
Gabriele Zybarth - Little Compton RI, US
International Classification:
C07H021/04
C12P019/34
A61K039/12
C12N007/00
C12N007/01
C12N015/00
C12N015/09
C12N015/63
C12N015/70
C12N015/74
US Classification:
435/320100, 435/235100, 435/091100, 424/199100, 424/204100, 424/205100, 536/023720
Abstract:
The present invention provides genetically engineered type I/type II hybrid BVDV viruses. The hybrid viruses, as well as the hybrid viral genome, can be used in immunogenic compositions and vaccines for protecting cattle from BVDV infection.