Inventors:
Juan A. Ruiz - Miami FL
James R. Maynard - Miami FL
Frederick Dombrose - Ventura CA
Assignee:
Dade Behring Inc. - Deerfield IL
International Classification:
G01N 33543
US Classification:
436518, 435 74, 435 794, 436547, 436548, 5303879
Abstract:
According to the present invention highly specific-low affinity antibodies are generated which allow for the assay of F1. 2 in bodily fluids that also contain prothrombin or other plasma proteins. Antibodies having the necessary properties for this assay are made using synthetic polypeptides which mimic the carboxy terminus of F1. 2.