Inventors:
Wieslaw Mieczyslaw Kazmierski - Durham NC, US
Chrisopher Joseph Aquino - Durham NC, US
Neil Bifulco - Durham NC, US
Eric Eugene Boros - Durham NC, US
Brian Andrew Chauder - Durham NC, US
Pek Yoke Chong - Durham NC, US
Maosheng Duan - Durham NC, US
Felix Deanda, Jr. - Durham NC, US
Cecilia Suarez Koble - Durham NC, US
Ed Williams McLean - Durham NC, US
Jennifer Poole Peckham - Durham NC, US
Angilique C Perkins - Durham NC, US
James Benjamin Thompson - Durham NC, US
Dana Vanderwall - Durham NC, US
Assignee:
SmithKline Beecham Corp. - Philadelphia PA
International Classification:
A61K 31/46
US Classification:
514304, 514319, 546125, 5483101
Abstract:
The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).