Inventors:
Suhaib Siddiqi - Burlington MA, US
Hernan Orgueira - Cambridge MA, US
Edyta Olejnik - Brookline MA, US
Subramanian Marappan - Brookline MA, US
Philip R. Buzby - Brockton MA, US
Atanu Roy - Woburn MA, US
Assignee:
Helicos Biosciences Corporation - Cambridge MA
International Classification:
C07H 21/04
US Classification:
536 243, 536 221, 536 231, 536 2433, 536 253, 536 2532, 514 42, 514 43, 514 52
Abstract:
The invention provides a family of tethered nucleotide analogs useful in sequencing nucleic acids containing a homopolymer region comprising, for example, two or more base repeats, and to sequencing methods using such tethered nucleotide analogs.