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Edward G Spack

from Sunnyvale, CA
Age ~70
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Also known as:
Edward George Spack, Edw G Spack, Edward G Spacht, Edward S Pack
Phone and address:
1037 W Knickerbocker Dr, Sunnyvale, CA 94087
Related to:
Barbara E Wright, 70Lorie SpackLaurel M Spack, 30
Connected to:
Amanda J Spack, 36James R Spack, 59John M Spack, 45Alyse Spackman, 27Amanda L Spackman, 49Brad E Spackman, 57Brett R Spackman, 52Cory Spackman, 50James W Spackman, 84John G Spackman, 62

Edward Spack Phones & Addresses

  • 1037 W Knickerbocker Dr, Sunnyvale, CA 94087
  • 1725 Wright Ave, Mountain View, CA 94043
  • Palo Alto, CA
  • Santa Clara, CA

Resumes

Resumes

Edward Spack Photo 1

Edward Spack

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Location:
United States
Edward Spack Photo 2

Motion Pictures And Film Professional

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Publications

Us Patents

Immunodominant Acetylcholine Receptor Alpha Subunit Peptide: Mhc Complexes

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US Patent:
20030144477, Jul 31, 2003
Filed:
Sep 30, 2002
Appl. No.:
10/261798
Inventors:
Edward Spack - Mountain View CA, US
Subhashini Arimilli - Greensboro NC, US
Shrikant Deshpande - Fremont CA, US
Nancy Wehner - Fremont CA, US
Assignee:
Corixa Corporation - Seattle WA
International Classification:
C07K014/74
C07H021/04
A61K038/17
US Classification:
530/350000, 514/012000, 536/023500
Abstract:
The present invention is directed to the treatment of autoimmune diseases, in particular of myasthenia gravis. This invention provides novel autoimmune dominant peptides derived from the acetylcholine receptor, as well as methods for preparing the peptides. The present invention further provides complexes comprising these peptides associated with an appropriate major histocompatibility complex (MHC) molecule and methods for making these complexes. The complexes of the present invention can be used therapeutically or prophylactically for treating myasthenia gravis.

Identification Of Potential Immunodominant Acetylcholine Receptor Alpha Subunit

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US Patent:
20050048066, Mar 3, 2005
Filed:
Mar 30, 2001
Appl. No.:
10/240035
Inventors:
Shrikant Deshpande - Fremont CA, US
Edward Spack - Mountain View CA, US
Nancy Wehner - Fremont CA, US
Subhashini Arimilli - Fremont CA, US
International Classification:
A61K039/00
US Classification:
424185100
Abstract:
The present invention is directed to the treatment of autoimmune diseases, in particular of . This invention provides novel autoimmune dominant peptides derived from the acetylcholine receptor, as well as methods for preparing the peptides. The present invention further provides complexes comprising these peptides associated with an appropriate major histocompatibility complex (MHC) molecule and methods for making these complexes. The complexes of the present invention can be used therapeutically or prophylactically for treating

Method For Monitoring T Cell Reactivity

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US Patent:
62181327, Apr 17, 2001
Filed:
Nov 24, 1997
Appl. No.:
8/977650
Inventors:
Edward G. Spack - Mountain View CA
Nancy G. Wehner - Fremont CA
Michael A. McCutcheon - Stanford CA
Assignee:
Anergen, Inc. - Redwood City CA
International Classification:
G01N 3353
G01N 33564
US Classification:
435 724
Abstract:
This invention provides a highly sensitive assay for the detection of T-cells reactive to an antigen by detecting a soluble factor whose secretion is induced by stimulation of the T-cell by the antigen. The assay includes an antigen-driven proliferation of specific T cells prior to restimulation with irradiated antigen presenting cells (APCs) and antigen. In exemplary embodiments the assay is used to enhance the detection limits of human peripheral blood mononuclear cells (PBMCs) secreting interferon-. gamma. (IFN-Y) and interleukin-2 (IL-2). The assay can be performed on previously frozen PBMCs, providing greater convenience in sample processing, multiple use of a single sample as an internal standard, and simultaneous analysis of samples collected at different time points.

Method For Monitoring T Cell Reactivity

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US Patent:
57503567, May 12, 1998
Filed:
May 31, 1996
Appl. No.:
8/657939
Inventors:
Edward G. Spack - Mountain View CA
Nancy G. Wehner - Fremont CA
Michael A. McCutcheon - Stanford CA
Assignee:
Anergen, Inc. - Redwood City CA
International Classification:
G01N 3353
US Classification:
435 724
Abstract:
This invention provides a highly sensitive assay for the detection of T-cells reactive to an antigen by detecting a soluble factor whose secretion is induced by stimulation of the T-cell by the antigen. The assay includes an antigen-driven proliferation of specific T cells prior to restimulation with irradiated antigen presenting cells (APCs) and antigen. The assay can be performed on previously frozen PBMCs, providing greater convenience in sample processing, multiple use of a single sample as an internal standard, and simultaneous analysis of samples collected at different time points.
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Edward G Spack from Sunnyvale, CA, age ~70 Get Report