US Patent:
20020012693, Jan 31, 2002
Inventors:
Kelman Cohen - Richmond VA, US
Robert Diegelmann - Richmond VA, US
Dorne Yager - Chesterfield VA, US
Judson Edwards - Mandeville LA, US
International Classification:
A61K009/70
A61K031/70
A61F013/00
US Classification:
424/446000, 514/023000, 514/057000, 442/123000
Abstract:
The invention provides wound dressings and methods of their use, especially for the treatment of chronic, non-healing wounds. The wound dressings are composed of a support matrix, such as cotton cellulose, and an active agent associated with the support matrix. The active agent may be a protease inhibitor or a protease sequestrant, in particular an inhibitor or sequestrant of a neutrophil-derived cationic protease such as elastase.