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Daniel T Kohlman

from Fishers, IN
Age ~56
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Also known as:
Daniel Diana Singletonko Kohlman, Dan T Kohlman, Daniel T Kohima, Daniel N
Related to:
Linda M Garland, 56Anita A Pfaehler, 66Michael Fahey, 66Danielle A Vanhook, 47
Connected to:
Chad M Kohlmann, 45Cindy J Kohlman, 64Franklin A Kohlmann, 29Ian N Kohlman, 34Kory A Kohlmann, 34Leah Kohlman, 67Olivia M Kohlmann, 36Raymond S Kohlmann, 97Scott T Kohlmann, 60Sheila D Kohlman, 58

Daniel Kohlman Phones & Addresses

  • Fishers, IN
  • Florence, KY
  • 6281 E Old Otto Ct S, Camby, IN 46113
  • Indianapolis, IN
  • Hamilton, IN
  • Toledo, OH
  • Edison, NJ

Industries

Pharmaceuticals

Resumes

Resumes

Daniel Kohlman Photo 1

Consultant Chemist At Eli Lilly And Company

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Location:
Indianapolis, Indiana Area
Industry:
Pharmaceuticals

Publications

Us Patents

Arylpiperazines Having Activity At The Serotonin 1A Receptor

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US Patent:
6358958, Mar 19, 2002
Filed:
Jan 3, 2001
Appl. No.:
09/753645
Inventors:
Daniel Timothy Kohlman - Indianapolis IN
Yao-Chang Xu - Fishers IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 31495
US Classification:
51425503
Abstract:
A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1 receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

Piperidine Derivatives Having Effects On Serotonin Related Systems

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US Patent:
6436964, Aug 20, 2002
Filed:
Nov 28, 2000
Appl. No.:
09/701406
Inventors:
Larry Wayne Hertel - Indianapolis IN
Daniel Timothy Kohlman - Camby IN
Sidney Xi Liang - Fishers IN
David Taiwai Wong - Indianapolis IN
Yao-Chang Xu - Fishers IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07D40506
US Classification:
514333, 546256
Abstract:
The present invention provides the compounds of the following formula: Wherein the variables are as defined in the specification and a method for inhibiting the reuptake of seretonin, antagonizing the 5-HT receptor and antagonizing the 5-HT receptor which comprises administering to a subject in need of such treatment an effective amount of the compound of above formula.

Arylpiperazines Having Activity At The Serotonin 1A Receptor

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US Patent:
6514976, Feb 4, 2003
Filed:
Apr 30, 2002
Appl. No.:
10/136101
Inventors:
Daniel Timothy Kohlman - Indianapolis IN
Yao-Chang Xu - Fishers IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 31495
US Classification:
51425301, 51425503, 544360, 544392, 544394
Abstract:
Described herein is a compound of the formula wherein Arâ is a mono or bicyclic aromatic or heteroaromatic radical substituted with one to three substituents selected from the group consisting of hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; R is hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio; R is phenyl, naphthyl or (C -C )cycloalkyl substituted with one or two substituents selected from the group consisting of hydrogen (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; R is selected from the group consisting of hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; X is â(C O)â; or a pharmaceutically acceptable salt racemate, optical isomer or solvate thereof.

Arylpiperazines Having Activity At The Serotonin 1A Receptor

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US Patent:
6645967, Nov 11, 2003
Filed:
Dec 18, 2001
Appl. No.:
10/022045
Inventors:
Daniel Timothy Kohlman - Indianapolis IN
Yao-Chang Xu - Fishers IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 31495
US Classification:
51425503, 51425301, 514649
Abstract:
Described herein is a method for potentiating the action of a serotonin reuptake inhibitor in increasing the availability of serotonin, norepinephrin and dopamine in the brain, by administering to a patient an effective amount of a compound of the formula wherein Arâ is a mono or bicyclic aryl or heteroaryl radical substituted with one to three substituents selected from the group consisting of hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; R is hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio; R is phenyl, naphthyl or (C -C )cycloalkyl substituted with one or two substituents selected from the group consisting of hydrogen (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; R is selected from the group consisting of hydrogen (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; X is â(C O)â; or a pharmaceutically acceptable salt, racemate, optical isomer or solvate thereof.

Arylpiperazines Having Activity At The Serotonin 1A Receptor

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US Patent:
6660859, Dec 9, 2003
Filed:
Dec 18, 2001
Appl. No.:
10/022043
Inventors:
Daniel Timothy Kohlman - Indianapolis IN
Yao-Chang Xu - Fishers IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07D295104
US Classification:
544392, 544360, 544394
Abstract:
Described herein is a series of aryl piperazine compounds of the formula: wherein Arâ is a mono or bicyclic aryl or heteroaryl radical substituted with one to three substituents selected from the group consisting of hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; R is hydrogen, (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio; R is phenyl, naphthyl or (C -C )cycloalkyl substituted with one or two substituents selected from the group consisting of hydrogen (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; R is selected from the group consisting of hydrogen (C -C )alkyl, (C -C )alkoxy, (C -C )alkylthio, (C -C )alkenyl, (C -C )alkynyl, (C -C )alkylhalo, (C -C )cycloalkyl, (C -C )cycloalkenyl or halo; X is â(C O)â, âCHOHâ or âCH â; or a pharmaceutically acceptable salt, racemate, optical isomer or solvate thereof.

Piperidine Derivatives As Reuptake Inhibitors

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US Patent:
6828332, Dec 7, 2004
Filed:
Feb 27, 2002
Appl. No.:
10/070130
Inventors:
Daniel Timothy Kohlman - Camby IN
Sidney Xi Liang - Hamden CT
Yao-Chang Xu - Fishers IN
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07D40102
US Classification:
514332, 514337, 546255, 5462804, 5462834
Abstract:
The present invention provides compounds of formula (I) and a method of inhibiting the reuptake of serotonin and antagonizing the serotonin receptor which comprises administering to a subject in need of such treatment an effective amount of a compound of formula (I).

Arylpiperazines Having Activity At The Serotonin 1A Receptor

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US Patent:
6946579, Sep 20, 2005
Filed:
Jul 2, 2003
Appl. No.:
10/613798
Inventors:
Alexander Glenn Godfrey - Greenwood IN, US
Daniel Timothy Kohlman - Indianapolis IN, US
John Cunningham O'Toole - Indianapolis IN, US
Yao-Chang Xu - Fishers IN, US
Tony Yantao Zhang - Indianapolis IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07C049/312
US Classification:
568377, 568312, 568313, 568320, 568349, 568376
Abstract:
A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

Arylpiperazines Having Activity At The Serotonin 1A Receptor

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US Patent:
7001908, Feb 21, 2006
Filed:
Apr 16, 2003
Appl. No.:
10/419063
Inventors:
Alexander Glenn Godfrey - Greenwood IN, US
Daniel Timothy Kohlman - Indianapolis IN, US
John Cunningham O'Toole - Indianapolis IN, US
Yao-Chang Xu - Fishers IN, US
Tony Yantao Zhang - Indianapolis IN, US
Assignee:
Avera Pharmaceuticals, Inc. - San Diego CA
Eli Lilly and Company - Indianapolis IN
International Classification:
A61K 31/497
C07D 401/00
US Classification:
51425301, 51425503, 544360
Abstract:
A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
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Daniel T Kohlman from Fishers, IN, age ~56 Get Report