Inventors:
Peter Van Bodine - Havertown PA, US
Dan Gazit - Charlottesville VA, US
International Classification:
A61K048/00
C07H021/04
C07K014/72
US Classification:
514044000, 435069100, 435320100, 435325000, 530350000, 536023500
Abstract:
This invention is directed to a BMP-6 ERE nucleic acid sequence, vectors, cells and compositions comprising same. This invention also provides methods for identification of estrogen agonists, antagonists and therapeutic applications of same. This invention also provides methods of treating conditions, which are associated with estrogen insufficiency or with lack of response to external estrogen or agonists thereof utilizing sequences, vectors, cells and/or compositions described herein.