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Brian R Chaikind

from Orinda, CA
Age ~39
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Related to:
Thomas L Norton, 33Caroline C Corcoran, 46Timothy J Corcoran, 50Jennifer Thomas, 39Kevin Thomas, 41Robert E Thomas, 47
Connected to:
Lauren N Chaikin, 43Marc P Chaikin, 81Suzan Chaiklin, 49Silvia E Chaikovski, 64Roberta G Chaildin, 71Brooke L Chailer, 38Mitchell J Chailland, 55Karla K Chaillet, 64Eduardo C Chaillo, 56Joy N Chaillou, 42

Brian Chaikind Phones & Addresses

  • 66 Stanton Ave, Orinda, CA 94563
  • Rockville, MD
  • Oakland, CA
  • Cambridge, MA
  • Baltimore, MD
  • Bethesda, MD
  • San Diego, CA

Resumes

Resumes

Brian Chaikind Photo 1

San Francisco Bay Area, Stati Uniti

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Location:
66 Stanton Ave, Orinda, CA 94563
Industry:
Chemicals
Work:
Zymergen, Inc. Jan 2018 - Mar 2020
Scientist Ii
Harvard University Mar 2014 - Feb 2016
Postdoctoral Researcher
Revolve Biotechnologies Mar 2013 - Mar 2014
Co-Founder
Johns Hopkins University Sep 2008 - Feb 2014
Ph.d., Chemical Biology
Scripps Institution of Oceanography Jul 2007 - Jun 2008
Staff Research Associate Ii
Education:
The Johns Hopkins University 2008 - 2013
Doctorates, Doctor of Philosophy, Biology, Philosophy The Johns Hopkins University 2008 - 2010
Master of Science, Masters, Biology Northwestern University 2003 - 2007
Bachelors, Bachelor of Arts, Bachelor of Science, Environmental Science
Skills:
Biochemistry
Scientific Writing
Molecular Biology
Fluorescence Microscopy
Mammalian Cell Culture
Organic Chemistry
Cell Culture
Chemical Biology
Genetic Engineering
Biotechnology
Dna Extraction
Pcr
Polymerase Chain Reaction
Research
Protein Engineering
Natural Products
Analytical Chemistry
Protein Purification
Directed Evolution
Bacterial Cell Culture
Protein Chemistry
Reverse Transcription Polymerase Chain Reaction
Robotics
Interests:
Gardening
Biofuels
Running
Marine Biology
Astronomy
Brewing Beer
Languages:
Spanish
Brian Chaikind Photo 2

Brian Chaikind

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Skills:
Human Rights

Publications

Us Patents

Htp Genomic Engineering Platform For Improving Fungal Strains

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US Patent:
20210284993, Sep 16, 2021
Filed:
Mar 19, 2021
Appl. No.:
17/207376
Inventors:
- EMERYVILLE CA, US
Jennifer Fredlund - Emeryville CA, US
Hassan Abdulla - Oakland CA, US
Paolo Boccazzi - Emeryville CA, US
Sean Poust - El Cerrito CA, US
Sara da Luz Areosa Cleto - Emeryville CA, US
Brian Chaikind - Oakland CA, US
Dylan Vaughan - Oakland CA, US
Kenneth S. Bruno - Walnut Creek CA, US
Patrick Westfall - Walnut Creek CA, US
Edyta Szewczyk - Walnut Creek CA, US
International Classification:
C12N 15/10
C12N 1/14
C12N 9/22
C12N 15/11
C12N 15/80
Abstract:
A HTP genomic engineering platform for improving filamentous fungal cells that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols is provided. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition. Methods for isolating clonal populations derived from individual fungal spores are also provided.

Htp Genomic Engineering Platform For Improving Fungal Strains

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US Patent:
20200123535, Apr 23, 2020
Filed:
Dec 20, 2019
Appl. No.:
16/723594
Inventors:
- Emeryville CA, US
Jennifer Fredlund - Emeryville CA, US
Hassan Abdulla - Emeryville CA, US
Paolo Boccazzi - Emeryville CA, US
Sean Poust - El Cerrito CA, US
Sara da Luz Areosa Cleto - Emeryville CA, US
Brian Chaikind - Oakland CA, US
Dylan Vaughan - Oakland CA, US
Kenneth S. Bruno - Walnut Creek CA, US
Patrick Westfall - Walnut Creek CA, US
Edyta Szewczyk - Walnut Creek CA, US
International Classification:
C12N 15/10
C12N 9/22
C12N 15/11
C12N 1/14
C12N 15/80
Abstract:
The present disclosure provides a HTP genomic engineering platform for improving filamentous fungal cells that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition.

Htp Genomic Engineering Platform For Improving Fungal Strains

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US Patent:
20200071693, Mar 5, 2020
Filed:
Oct 11, 2019
Appl. No.:
16/600062
Inventors:
- EMERYVILLE CA, US
Jennifer Fredlund - Emeryville CA, US
Hassan Abdulla - Emeryville CA, US
Paolo Boccazzi - Emeryville CA, US
Sean Poust - El Cerrito CA, US
Sara da Luz Areaosa Cleto - Emeryville CA, US
Brian Chaikind - Oakland CA, US
Dylan Vaughan - Oakland CA, US
Kenneth S. Bruno - Walnut Creek CA, US
Patrick Westfall - Walnut Creek CA, US
Edyta Szewczyk - Walnut Creek CA, US
International Classification:
C12N 15/10
C12N 1/14
C12N 15/11
C12N 9/22
C12N 15/80
Abstract:
The present disclosure provides a HTP genomic engineering platform for improving filamentous fungal cells that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition.

Programmable Cas9-Recombinase Fusion Proteins And Uses Thereof

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US Patent:
20190367891, Dec 5, 2019
Filed:
Aug 9, 2017
Appl. No.:
16/324476
Inventors:
- Cambridge MA, US
Brian Chaikind - Oakland CA, US
Jeffrey L. Bessen - Somerville MA, US
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
C12N 9/12
C12N 9/22
C12N 15/113
C07K 4/00
Abstract:
Some aspects of this disclosure provide a fusion protein comprising a guide nucleotide sequence-programmable DNA binding protein domain (e.g., a nuclease-inactive variant of Cas9 such as dCas9), an optional linker, and a recombinase catalytic domain (e.g., a tyrosine recombinase catalytic domain or a serine recombinase catalytic domain such as a Gin recombinase catalytic domain). This fusion protein can recombine DNA sites containing a minimal recombinase core site flanked by guide RNA-specified sequences. The instant disclosure represents a step toward programmable, scarless genome editing in unmodified cells that is independent of endogenous cellular machinery or cell state.

Compositions For Targeted Dna Methylation And Their Use

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US Patent:
20170058268, Mar 2, 2017
Filed:
Mar 11, 2015
Appl. No.:
15/124917
Inventors:
- Baltimore MD, US
Brian Chaikind - Baltimore MD, US
International Classification:
C12N 9/10
C12N 15/62
C12Q 1/68
C12Q 1/48
Abstract:
The present invention provides an in vitro directed evolution selection system to create modified methyltransferases which improve methyltransferase specificity and use it to optimize and provide fusion proteins comprising a zinc finger methyltransferase derived from M.SssI. The resulting fusion proteins show increased target methylation specificity and greatly decreased non-target methylation compared to wild-type enzyme activity. Methods of use of such fusion proteins in both prokaryotic and eukaryotic cells are also provided.
Control profile
Brian R Chaikind from Orinda, CA, age ~39 Get Report