Inventors:
Lori R. Bernstein - Montgomery Village MD, US
Barry M. Datlof - Montgomery Village MD, US
International Classification:
A61K 38/24
A61K 38/08
A61K 31/57
A61K 31/573
A61K 31/585
A61K 31/536
A61K 31/566
A61K 31/437
A61K 31/4196
A61K 31/4545
A61K 31/565
A61K 31/09
A61K 31/05
A61K 31/661
A61K 31/567
A61K 38/09
Abstract:
The present invention discloses methods of prevention of oocyte and fetal aneuploidy, birth defects, miscarriages and infertility in women. The three therapies, disclosed herein, the hormone normalization therapy, the aromatase inhibitor-hormone normalization therapy, and the low responder hormone normalization therapy with estrogenic supplementation focus on restoring young hormonal levels in women in order to prevent female infertility and miscarriages, guide follicular and oocyte maturation, follicular responsiveness, and promote correct chromosomal segregation in oocytes and early embryos.