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Axel H Metzger

from Jackson, NJ
Age ~60

Axel Metzger Phones & Addresses

  • 177 S Stump Tavern Rd, Jackson, NJ 08527 (848) 222-4901
  • 80 Roberts Dr, Bedford, MA 01730 (781) 538-5059
  • 6702 Ravens Crest Dr, Plainsboro, NJ 08536 (609) 799-5081
  • 6 Buxton Dr, Hightstown, NJ 08520 (609) 371-5894
  • East Windsor, NJ
  • Austin, TX
  • Waltham, MA

Work

Company: Baker & McKenzie Address:

Professional Records

Lawyers & Attorneys

Axel Metzger Photo 1

Axel Metzger - Lawyer

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Office:
Baker & McKenzie
ISLN:
922400101

Resumes

Resumes

Axel Metzger Photo 2

Consultant At Advanced Proteome Therapeutics Inc.

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Position:
Consultant at Advanced Proteome Therapeutics Inc.
Location:
Greater Boston Area
Industry:
Pharmaceuticals
Work:
Advanced Proteome Therapeutics Inc. since Feb 2012
Consultant

Palatin Technologies Dec 2006 - Oct 2010
Associate Director

Pharmacopeia 2002 - 2006
Reserach Fellow

Pharmacopeia Drug Discovery, Inc. Jul 1997 - Nov 2006
Senior Research Fellow

UT at Austin 1995 - 1997
Post Doc
Education:
Villanova University 2011 - 2011
Master Certificate, Applied Project Management;
Technische Universität München
Skills:
Drug Discovery
Medicinal Chemistry
Lead Change
Drug Development
Drug Design
Organic Synthesis
Organic Chemistry
GPCRs
Biotechnology
HPLC
LC-MS
ADME
Languages:
English, German
Axel Metzger Photo 3

Axel Metzger

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Publications

Us Patents

N-Heterocyclic Inhibitors Of Tnf-Α Expression

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US Patent:
6906067, Jun 14, 2005
Filed:
Jun 26, 2001
Appl. No.:
09/891750
Inventors:
Kevin Joseph Moriarty - Norristown PA, US
Yvonne Shimshock - Hillsborough NJ, US
Gulzar Ahmed - Yardley PA, US
Junjun Wu - Malden MA, US
James Wen - Dayton NJ, US
Wei Li - Acton MA, US
Shawn David Erickson - Leonia NJ, US
Jeffrey John Letourneau - East Windsor NJ, US
Edward McDonald - Banstead, GB
Katerina Leftheris - Skillman NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Zahid Hussain - Monmouth Junction NJ, US
Ian Henderson - Hopewell NJ, US
Axel Metzger - East Windsor NJ, US
John J. Baldwin - Gwynedd Valley PA, US
Alaric J. Dyckman - Lawrenceville NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
Pharmaceopeia, Inc. - Cranbury NJ
International Classification:
C07D251/40
C07D251/48
C07D251/52
A61K031/53
A61P035/00
US Classification:
514241, 544197, 544198, 544208, 544209, 544213, 544217, 544218
Abstract:
N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

N-Heterocyclic Inhibitors Of Tnf-Α Expression

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US Patent:
7253174, Aug 7, 2007
Filed:
Jul 12, 2006
Appl. No.:
11/485075
Inventors:
Gulzar Ahmed - Yardley PA, US
Axel Metzger - East Windsor NJ, US
Ian Henderson - Hopewell NJ, US
David J. Diller - Hightstown NJ, US
Jun Wen - Dayton NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Katerina Leftheris - Skillman NJ, US
Chunjian Liu - Pennington NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
Pharmacopeia, Inc. - Cranbury NJ
International Classification:
C07D 239/48
A61K 31/505
US Classification:
514256, 514275, 544323, 544324, 544326, 544328, 544329
Abstract:
N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula (I):Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

N-Heterocyclic Inhibitors Of Tnf-Α Expression

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US Patent:
7479495, Jan 20, 2009
Filed:
Jun 2, 2005
Appl. No.:
11/143430
Inventors:
Kevin Joseph Moriarty - Norristown PA, US
Yvonne Shimshock - Hillsborough NJ, US
Gulzar Ahmed - Yardley PA, US
Junjun Wu - Malden MA, US
James Wen - Dayton NJ, US
Wei Li - Acton MA, US
Shawn David Erickson - Leonia NJ, US
Jeffrey John Letourneau - East Windsor NJ, US
Edward McDonald - Banstead, GB
Katerina Leftheris - Skillman NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Zahid Hussain - Monmouth Junction NJ, US
Ian Henderson - Hopewell NJ, US
Axel Metzger - East Windsor NJ, US
John J. Baldwin - Gwynedd Valley PA, US
Alaric J. Dyckman - Lawrenceville NJ, US
Assignee:
Pharmacopeia, Inc. - Cranbury NJ
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 239/32
C07D 239/48
C07D 239/50
C07D 401/04
C07D 401/12
C07D 403/04
C07D 403/12
A61K 31/505
A61K 31/506
A61P 19/02
A61P 35/00
US Classification:
514269, 514272, 514273, 514275, 544317, 544320, 544321, 544323, 544326
Abstract:
N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I:Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

8-Heteroarylpurine Mnk2 Inhibitors For Treating Metabolic Disorders

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US Patent:
7951803, May 31, 2011
Filed:
Mar 9, 2007
Appl. No.:
11/684262
Inventors:
Andrew G. Cole - Robbinsville NJ, US
Joan J. Zhang - Plainsboro NJ, US
Zahid Hussain - Monmouth Junction NJ, US
David J. Diller - East Windsor NJ, US
Axel Metzger - East Windsor NJ, US
Gulzar Ahmed - Voorhees NJ, US
Ian Henderson - Hopewell NJ, US
Assignee:
Pharmacopeia, LLC - San Diego CA
International Classification:
C07D 473/32
A61K 31/52
A61P 3/10
A61P 3/04
A61P 19/02
C07D 409/12
C07D 239/26
C07D 239/28
US Classification:
5142342, 51425216, 51426321, 51426322, 51426323, 5142634, 544118, 544277, 544162, 544324, 544326, 544332, 546232
Abstract:
Compounds of the formula.

Melanocortin Receptor-Specific Spiro-Piperidine Compounds

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US Patent:
8263608, Sep 11, 2012
Filed:
Mar 29, 2011
Appl. No.:
13/074070
Inventors:
Yi-Qun Shi - East Brunswick NJ, US
John H. Dodd - Flemington NJ, US
Elizabeth G. Rowley - Kendal Park NJ, US
Gary L. Olson - Mountainside NJ, US
Axel Metzger - East Windsor NJ, US
Assignee:
Palatin Technologies, Inc. - Cranbury NJ
International Classification:
A61K 31/415
A61K 31/445
A61K 31/454
A61K 31/4545
C07D 221/00
C07D 233/00
US Classification:
514278, 514323, 546 15, 546 17, 546 18, 546184, 546192, 5483001
Abstract:
Melanocortin receptor-specific compounds of formula I below:.

N-Heterocyclic Inhibitors Of Tnf-Alpha Expression

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US Patent:
8044040, Oct 25, 2011
Filed:
Jul 16, 2007
Appl. No.:
11/778219
Inventors:
Gulzar Ahmed - Yardley PA, US
Axel Metzger - East Windsor NJ, US
Ian Henderson - Hopewell NJ, US
David J. Diller - Hightstown NJ, US
Jun Wen - Dayton NJ, US
Stephen T. Wrobleski - Whitehouse Station NJ, US
Katerina Leftheris - Skillman NJ, US
Chunjian Liu - Pennington NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
Pharmacopeia, Inc. - Cranbury NJ
International Classification:
C07D 239/48
A61K 31/505
US Classification:
514218, 514256, 514274, 514275, 540575, 544317, 544323, 544324, 544326, 544328, 544329
Abstract:
N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula (I):.

N-Heterocyclic Inhibitors Of Tnf-Alpha Expression

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US Patent:
20030139435, Jul 24, 2003
Filed:
Jun 26, 2002
Appl. No.:
10/183179
Inventors:
Gulzar Ahmed - Yardley PA, US
Axel Metzger - East Windsor NJ, US
Ian Henderson - Hopewell NJ, US
David Diller - Hightstown NJ, US
James Wen - Dayton NJ, US
Stephen Wrobleski - Whitehouse Station NJ, US
Katerina Leftheris - Skillman NJ, US
International Classification:
A61K031/506
A61K031/505
C 07D 4 1/02
C 07D 4 3/02
A61K031/4439
US Classification:
514/275000, 514/352000, 514/336000, 544/330000, 544/331000, 546/268100, 546/308000
Abstract:
N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula (I): Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF- expression utilizing compounds of the present invention are also disclosed.

Substituted 2-Aminothiazoles For Treating Neurodegenerative Diseases

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US Patent:
20090005568, Jan 1, 2009
Filed:
Aug 18, 2006
Appl. No.:
11/465569
Inventors:
Andrew G. Cole - Robbinsville NJ, US
Axel Metzger - East Windsor NJ, US
Ian Henderson - Hopewell NJ, US
Assignee:
Pharmacopeia Drug Discovery, Inc. - Cranbury NJ
International Classification:
A61K 31/454
A61K 31/427
C07D 277/02
C07D 401/04
A61P 25/28
US Classification:
546209, 548194, 514370, 514326
Abstract:
The invention relates to substituted 2-aminothiazole derivatives useful in treating disorders that are mediated by Areceptor function, including neurodegenerative diseases including Parkinson's disease and inflammation. The compounds have general formula I:

Isbn (Books And Publications)

Rechtsgeschafte uber Das Droit Moral Im Deutschen Und Franzosischen Urheberrecht

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Author

Axel Metzger

ISBN #

3406487890

Axel H Metzger from Jackson, NJ, age ~60 Get Report