US Patent:
20130209362, Aug 15, 2013
Inventors:
John L. Neumeyer - Wayland MA, US
Yu-Gui Si - Shanghai, CN
Anna W. Sromek - Belmont MA, US
Assignee:
The McLean Hospital Corporation - Belmont MA
International Classification:
A61K 51/04
C07D 221/18
US Classification:
424 189, 546 75, 424 185, 514284
Abstract:
The invention features 2-alkoxy-11-hydroxyaporphine derivatives that selectively bind Dreceptors. The compounds are useful for imaging Dreceptors and for the treatment of diseases, such as Parkinson's disease, sexual dysfunction, and depressive disorders.