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Andrei L Laikhter

from Arlington, MA
Age ~64
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Also known as:
Natalia Laikhter, Natalla Laikhter, Rei Laikhter, Laikhter Andrei, Andrei R, A R, Sundeep Deorah
Phone and address:
36 Oakland Ave, Arlington, MA 02476
(319) 621-3002
Related to:
Daniel LaikhterLinda Belote, 83Alan KingSundeep Deorah, 49Danny Williams
Connected to:
Paul C Laikowski, 87Amanda J Lail, 48Antoinette H Lail, 60Barbara A Lail, 78Brad D Lail, 39Christy J Lail, 65Clifford R Lail, 28Cory M Lail, 38Danny R Lail, 76Ellen G Lail, 58

Andrei Laikhter Phones & Addresses

  • 36 Oakland Ave, Arlington, MA 02476 (319) 621-3002
  • 20 Captain Parker Arms #11, Lexington, MA 02421
  • 5 Cherry Ave, Iowa City, IA 52240 (319) 338-3772
  • 10405 Hunter Ridge Dr, Oakton, VA 22124 (703) 319-0770
  • 312 13Th St NW #3, Charlottesville, VA 22903 (434) 296-1274
  • Burlington, MA
  • West Roxbury, MA
  • Reston, VA
  • Enfield, CT

Work

Company: Chemgenes May 1, 2008 Position: Chief scientific officer

Education

School / High School: University of Virginia 1994 to 1996 Specialities: Chemistry

Skills

Biotechnology • Hplc • Chemistry • Life Sciences • Medicinal Chemistry • Dna • Validation • Organic Chemistry • Purification • Mass Spectrometry • Chromatography • Diagnostics • Technology Transfer • Science • Research • Lifesciences • Laboratory • Biochemistry • Drug Discovery • Protein Chemistry • Molecular Biology • Genomics • Assay Development • Lc Ms • Cell • Drug Development • Cell Culture • Cell Biology • Dna Sequencing • Protein Purification • Organic Synthesis • Pharmaceutical Industry • R&D • Biopharmaceuticals • Immunology • Pcr • Genetics • Commercialization • Polymerase Chain Reaction

Industries

Biotechnology

Resumes

Resumes

Andrei Laikhter Photo 1

Chief Scientific Officer

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Location:
Arlington, MA
Industry:
Biotechnology
Work:
Chemgenes
Chief Scientific Officer
Integrated Dna Technologies 1999 - 2008
Vice President, Chemistry Research
Education:
University of Virginia 1994 - 1996
Skills:
Biotechnology
Hplc
Chemistry
Life Sciences
Medicinal Chemistry
Dna
Validation
Organic Chemistry
Purification
Mass Spectrometry
Chromatography
Diagnostics
Technology Transfer
Science
Research
Lifesciences
Laboratory
Biochemistry
Drug Discovery
Protein Chemistry
Molecular Biology
Genomics
Assay Development
Lc Ms
Cell
Drug Development
Cell Culture
Cell Biology
Dna Sequencing
Protein Purification
Organic Synthesis
Pharmaceutical Industry
R&D
Biopharmaceuticals
Immunology
Pcr
Genetics
Commercialization
Polymerase Chain Reaction

Publications

Us Patents

Compounds And Methods For Labeling Oligonucleotides

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US Patent:
7476735, Jan 13, 2009
Filed:
May 22, 2006
Appl. No.:
11/438606
Inventors:
Andrei Laikhter - Iowa City IA, US
Joseph A. Walder - Chicago IL, US
Mark Behlke - Coralville IA, US
Mikhail Podyminogin - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C07H 19/04
C07H 21/00
C12Q 1/68
C07C 245/00
C07K 16/00
US Classification:
536 266, 536 2532, 435 6, 534558, 5303913
Abstract:
The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.

Compounds And Methods For Labeling Oligonucleotides

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US Patent:
7605243, Oct 20, 2009
Filed:
Jan 12, 2009
Appl. No.:
12/352125
Inventors:
Andrei Laikhter - Iowa City IA, US
Joseph A. Walder - Chicago IL, US
Mark Behlke - Coralville IA, US
Mikhail Podyminogin - Coralville IA, US
Yawfui Yong - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C07H 21/04
C07H 19/04
G01N 15/06
C12Q 1/68
US Classification:
536 231, 536 243, 536 266, 435 6, 422 681
Abstract:
The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.

Compounds And Methods For Labeling Oligonucleotides

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US Patent:
7645872, Jan 12, 2010
Filed:
Aug 4, 2009
Appl. No.:
12/535220
Inventors:
Andrei Laikhter - Iowa City IA, US
Joseph A. Walder - Chicago IL, US
Mark Behlke - Coralville IA, US
Mikhail Podyminogin - Coralville IA, US
Yawfui Yong - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C07H 19/04
C07H 21/04
B01L 3/00
C07J 21/00
C07D 225/02
C12Q 1/68
G01N 33/53
US Classification:
536 266, 536 231, 530350, 435 6, 435 71, 435 72, 540 6, 540464, 422 61
Abstract:
The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.

Methods Of Detecting Fluorescence With Anthraquinone Quencher Dyes

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US Patent:
7803536, Sep 28, 2010
Filed:
Sep 19, 2003
Appl. No.:
10/666998
Inventors:
Mark Aaron Behlke - Coralville IA, US
Lingyan Huang - Coralville IA, US
Andrei Laikhter - Iowa City IA, US
Yawfui Yong - Iowa City IA, US
Scott Rose - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C12Q 1/68
C07C 45/27
US Classification:
435 6, 552208
Abstract:
The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.

Compounds And Methods For Labeling Oligonucleotides

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US Patent:
7803936, Sep 28, 2010
Filed:
Nov 23, 2009
Appl. No.:
12/623811
Inventors:
Andrei Laikhter - Iowa City IA, US
Joseph A. Walder - Chicago IL, US
Mark Behlke - Coralville IA, US
Mikhail Podyminogin - Coralville IA, US
Yawfui Yong - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C07H 19/04
C07J 21/00
C07D 225/02
C12Q 1/68
G01N 33/53
C07K 1/00
B01L 3/00
US Classification:
536 266, 536 231, 540 6, 540464, 435 6, 435 71, 435 72, 530350, 422 61
Abstract:
The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below.

Synthesis Of Novel Azo-Dyes And Their Use In Oligonucleotide Synthesis

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US Patent:
7956169, Jun 7, 2011
Filed:
Jun 16, 2010
Appl. No.:
12/816527
Inventors:
Andrei Laikhter - Lexington MA, US
Suresh C. Srivastava - Burlington MA, US
Naveen P. Srivastava - Burlington MA, US
Assignee:
ChemGenes Corporation - Wilmington MA
International Classification:
C09B 56/16
C09B 29/40
C12Q 1/68
US Classification:
534611, 534774, 534777, 435 6
Abstract:
The invention provides a novel group of azo quencher compositions that are useful as quenchers of fluorescence and to methods for making and using them. The quenchers contain an azo bond and 1,3,3-trimethyl-2-methyleneindoline ring system. The quenchers can be derivatized to facilitate their conjugation to a variety of biologically relevant compounds, including lipids, nucleic acids, peptides, proteins, and the like.

Compounds And Methods For Labeling Oligonucleotides

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US Patent:
8030460, Oct 4, 2011
Filed:
Aug 10, 2010
Appl. No.:
12/853741
Inventors:
Andrei Laikhter - Iowa City IA, US
Joseph A. Walder - Chicago IL, US
Mark Behlke - Coralville IA, US
Mikhail Podyminogin - Coralville IA, US
Yawfui Yong - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C07C 245/00
C12Q 1/68
C07H 21/00
C07H 21/02
C07K 16/00
US Classification:
534558, 536 231, 536 242, 536 2532, 536 266, 435 6, 5303913
Abstract:
A compound having the general formula shown below:.

Fluorescence Quenching Azo Dyes, Their Methods Of Preparation And Use

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US Patent:
8084588, Dec 27, 2011
Filed:
Oct 16, 2008
Appl. No.:
12/252721
Inventors:
Andrei Laikhter - Iowa City IA, US
Mark Aaron Behlke - Coralville IA, US
Joseph Walder - Chicago IL, US
Kevin William Roberts - Iowa City IA, US
Yawfui Yong - Coralville IA, US
Assignee:
Integrated DNA Technologies, Inc. - Skokie IL
International Classification:
C09B 29/085
C12Q 1/68
US Classification:
534876
Abstract:
Disclosed is a group of azo quencher compositions useful as fluorescence quenchers having the general structure of formula 1, methods of making or using the compositions, and kits comprising the composition.
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Andrei L Laikhter from Arlington, MA, age ~64 Get Report