US Patent:
20130164256, Jun 27, 2013
Inventors:
Chung-Ming Hsieh - Newton MA, US
Tariq Ghayur - Holliston MA, US
Lorenzo Benatuil - Northborough MA, US
Yuliya Kutskova - Northborough MA, US
John Memmott - Framingham MA, US
Jennifer Perez - Worcester MA, US
Suju Zhong - Shrewsbury MA, US
Carrie Goodreau - Ludlow MA, US
Anca Clabbers - Rutland MA, US
Assignee:
ABBVIE INC. - North Chicago IL
International Classification:
C07K 16/24
A61K 45/06
A61K 47/48
A61K 39/395
C07K 16/46
G01N 33/68
US Classification:
424 852, 5303892, 5303873, 53038823, 435188, 5303913, 5303917, 536 2353, 4353201, 435328, 435335, 4352523, 435419, 4352542, 435 696, 4241581, 4241331, 435 792, 435 71, 436501
Abstract:
Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (TNF-α), e.g., human TNF-α, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.