Inventors:
- Austin TX, US
Thomas Boland - El Paso TX, US
Hector P. Del Castillo - El Paso TX, US
Binata Joddar - El Paso TX, US
Alfredo Ornelas Sanchez - Austin TX, US
Javier Hernandez Ortega - El Paso TX, US
Phillip T. Baily - El Paso TX, US
International Classification:
C07D 209/08
C07D 405/12
C07D 403/12
C07H 15/26
Abstract:
Crosslinkers of an amide or thiocarbamate of 7-nitroindoline were prepared with at least two attached reactive groups for crosslinking capability. The photo-cleavability of the invented crosslinkers is based on the known photolysis behavior of N-acyl-7-nitroindolines, and the photolysis behavior of amides and thiocarbamates of 7-nitroindolines. These crosslinkers enable crosslinking of biopolymers, which can be reversed by illumination with light.